Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   DQM48_RS08945 Genome accession   NZ_LS483348
Coordinates   1745678..1746199 (-) Length   173 a.a.
NCBI ID   WP_228380494.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC8738     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1740678..1751199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM48_RS08915 (NCTC8738_01886) - 1740990..1741928 (-) 939 WP_020917484.1 3'-5' exoribonuclease YhaM family protein -
  DQM48_RS08920 (NCTC8738_01887) rmuC 1741918..1743192 (-) 1275 WP_020917485.1 DNA recombination protein RmuC -
  DQM48_RS08925 (NCTC8738_01888) - 1743194..1743826 (-) 633 WP_020917486.1 thiamine diphosphokinase -
  DQM48_RS08930 (NCTC8738_01889) rpe 1743819..1744481 (-) 663 WP_020917487.1 ribulose-phosphate 3-epimerase -
  DQM48_RS08935 (NCTC8738_01890) rsgA 1744488..1745360 (-) 873 WP_058814253.1 ribosome small subunit-dependent GTPase A -
  DQM48_RS08945 (NCTC8738_01892) comE/comE2 1745678..1746199 (-) 522 WP_228380494.1 LytR/AlgR family response regulator transcription factor Regulator
  DQM48_RS10545 (NCTC8738_01893) comE/comE2 1746184..1746411 (-) 228 WP_228380495.1 hypothetical protein Regulator
  DQM48_RS08950 (NCTC8738_01894) comD/comD2 1746969..1747781 (-) 813 WP_172454536.1 sensor histidine kinase Regulator
  DQM48_RS08955 (NCTC8738_01896) - 1748698..1748991 (-) 294 WP_020917489.1 bacteriocin immunity protein -
  DQM48_RS08960 (NCTC8738_01897) - 1749019..1749324 (-) 306 WP_020917490.1 bacteriocin immunity protein -
  DQM48_RS08965 - 1749337..1749486 (-) 150 WP_020917491.1 hypothetical protein -
  DQM48_RS08970 (NCTC8738_01898) rsmA 1749893..1750765 (-) 873 WP_111699071.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -

Sequence

Protein


Download         Length: 173 a.a.        Molecular weight: 20445.84 Da        Isoelectric Point: 9.9341

>NTDB_id=1137840 DQM48_RS08945 WP_228380494.1 1745678..1746199(-) (comE/comE2) [Streptococcus lutetiensis strain NCTC8738]
MAKAIREKSRTATIVFVTTYSEFMLLTYRAQVSALNFIDKTDKDDAIKDNFKKCLQKVFEDQGFNIPKKIFVFENNKTKI
RIPLEDILYFETAESHRLKLITKTGQCHFYGSIKEVMQANQKLFRCHKSYLINLNNIVRLDKKEGLVYFDDDKACYVSRK
YIKDLRSKMENLK

Nucleotide


Download         Length: 522 bp        

>NTDB_id=1137840 DQM48_RS08945 WP_228380494.1 1745678..1746199(-) (comE/comE2) [Streptococcus lutetiensis strain NCTC8738]
GTGGCTAAGGCGATAAGGGAAAAATCACGAACAGCGACAATTGTTTTTGTGACGACTTACTCTGAATTCATGTTATTGAC
TTATCGAGCTCAAGTTAGTGCACTTAATTTTATTGATAAAACAGATAAAGATGATGCGATAAAAGATAATTTTAAAAAAT
GCTTGCAAAAGGTCTTTGAGGACCAAGGTTTTAACATTCCTAAGAAAATATTTGTTTTTGAAAATAACAAAACGAAAATC
CGCATTCCCTTGGAAGATATCCTTTATTTTGAAACTGCGGAAAGTCATCGCCTGAAGTTGATTACAAAAACTGGGCAATG
TCATTTTTATGGTTCAATCAAAGAAGTGATGCAAGCTAATCAGAAATTATTTAGATGTCATAAATCATATCTGATTAACC
TAAATAATATTGTTAGGTTAGATAAAAAAGAAGGTTTGGTTTATTTTGACGATGATAAAGCTTGTTATGTTTCTAGAAAA
TATATCAAAGACTTAAGGTCAAAAATGGAAAATCTGAAATAG

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(80-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus equinus JB1

96.532

100

0.965
  comE/comE1 Streptococcus equinus JB1

45.294

98.266

0.445
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.5

100

0.382
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.5

100

0.382
  comE/blpR Streptococcus mutans UA159

39.053

97.688

0.382

Multiple sequence alignment