Detailed information NTG1137841

Bioinformatically predicted

Overview

• Name: comD/comD2
• Type: Regulator
• Locus tag: DQM48_RS08950
• Genome accession: NZ_LS483348
• Coordinates: 1746969..1747781 (-)
• Length: 270 a.a.
• NCBI ID: WP_172454536.1
• Uniprot ID: -
• Organism: Streptococcus lutetiensis strain NCTC8738
• Function: phosphorylation of ComE (predicted from homology) Competence regulation

Genomic Context

Location: 1741969..1752781

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM48_RS08925 (NCTC8738_01888)	-	1743194..1743826 (-)	633	WP_020917486.1	thiamine diphosphokinase	-
DQM48_RS08930 (NCTC8738_01889)	rpe	1743819..1744481 (-)	663	WP_020917487.1	ribulose-phosphate 3-epimerase	-
DQM48_RS08935 (NCTC8738_01890)	rsgA	1744488..1745360 (-)	873	WP_058814253.1	ribosome small subunit-dependent GTPase A	-
DQM48_RS08945 (NCTC8738_01892)	comE/comE2	1745678..1746199 (-)	522	WP_228380494.1	LytR/AlgR family response regulator transcription factor	Regulator
DQM48_RS10545 (NCTC8738_01893)	comE/comE2	1746184..1746411 (-)	228	WP_228380495.1	hypothetical protein	Regulator
DQM48_RS08950 (NCTC8738_01894)	comD/comD2	1746969..1747781 (-)	813	WP_172454536.1	sensor histidine kinase	Regulator
DQM48_RS08955 (NCTC8738_01896)	-	1748698..1748991 (-)	294	WP_020917489.1	bacteriocin immunity protein	-
DQM48_RS08960 (NCTC8738_01897)	-	1749019..1749324 (-)	306	WP_020917490.1	bacteriocin immunity protein	-
DQM48_RS08965	-	1749337..1749486 (-)	150	WP_020917491.1	hypothetical protein	-
DQM48_RS08970 (NCTC8738_01898)	rsmA	1749893..1750765 (-)	873	WP_111699071.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
DQM48_RS08975 (NCTC8738_01899)	rnmV	1750888..1751457 (-)	570	WP_043895125.1	ribonuclease M5	-
DQM48_RS08980 (NCTC8738_01900)	-	1751450..1752220 (-)	771	WP_003066600.1	TatD family hydrolase	-

Sequence

Protein

• Length: 270 a.a.
• Molecular weight: 30800.02 Da
• Isoelectric Point: 4.5454

>NTDB_id=1137841 DQM48_RS08950 WP_172454536.1 1746969..1747781(-) (comD/comD2) [Streptococcus lutetiensis strain NCTC8738]
MDAVAIVKPFHNTVNDAIRGIVAFIYLILLFVFLFYLNFRHGQEQKNELLRNQEMELAALENYSKHVESLYQEVRSFRHD
YANVLMSLKVGIDQGNLDDIKKIYNEITANSTKLVKNNKFDLTRLANIIDSGVKSFMSAKFLQAENQGVAISLEVAEKME
NPSMPLIYYIRILSILFDNAIEAALESETPEISVANFYQDGNFVFMIENSTKEKSVDLTKIFERGYSTKGENCGLGLATL
MDFQDDDENLSVETRSSDYTFTQVVRIFDA

Nucleotide

• Length: 813 bp

>NTDB_id=1137841 DQM48_RS08950 WP_172454536.1 1746969..1747781(-) (comD/comD2) [Streptococcus lutetiensis strain NCTC8738]
ATGGATGCCGTTGCTATTGTAAAACCTTTTCATAATACTGTTAACGATGCAATAAGGGGAATTGTTGCTTTCATTTATCT
CATCCTTCTTTTTGTCTTCCTCTTTTATCTTAATTTCCGTCATGGGCAAGAGCAGAAAAATGAATTGCTTCGTAACCAGG
AAATGGAATTGGCGGCCTTGGAAAATTATAGCAAGCACGTGGAGAGTTTGTATCAGGAGGTTCGCAGTTTCAGGCATGAC
TACGCTAATGTCCTGATGAGTTTAAAGGTTGGAATTGATCAAGGCAATCTTGATGACATCAAGAAAATTTACAACGAAAT
CACAGCCAATTCGACGAAGCTAGTCAAGAATAATAAATTTGACCTGACTCGCTTGGCTAACATCATAGACAGCGGCGTCA
AAAGCTTCATGTCAGCTAAATTTTTGCAAGCCGAAAATCAAGGGGTTGCAATTAGTCTAGAAGTCGCCGAAAAAATGGAA
AATCCTAGCATGCCATTAATTTATTACATTCGAATTTTGTCGATTCTGTTTGATAATGCCATAGAAGCCGCTTTGGAGTC
AGAAACTCCAGAAATCTCAGTCGCTAATTTTTACCAAGATGGTAACTTTGTTTTCATGATTGAGAATTCAACTAAGGAAA
AATCAGTGGATTTAACTAAGATTTTTGAGCGTGGCTACTCAACTAAGGGAGAAAATTGTGGACTTGGTCTAGCCACACTA
ATGGATTTCCAAGATGACGACGAAAATCTGTCAGTTGAAACCCGCAGCTCAGATTACACATTTACACAAGTTGTCCGAAT
TTTTGATGCATAA

Domains

Predicted by InterproScan.

• GHKL domain (HATPase_c_5) (170-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comD/comD2	Streptococcus equinus JB1	87.778	100	0.878
comD/comD3	Streptococcus equinus JB1	83.026	100	0.833
comD/comD1	Streptococcus equinus JB1	46.32	85.556	0.396
comD/blpH	Streptococcus mutans UA159	41.767	92.222	0.385