Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQM48_RS07445 Genome accession   NZ_LS483348
Coordinates   1453902..1454612 (-) Length   236 a.a.
NCBI ID   WP_020917222.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC8738     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1448902..1459612
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM48_RS07430 (NCTC8738_01571) rnc 1450840..1451526 (-) 687 WP_020917219.1 ribonuclease III -
  DQM48_RS07435 (NCTC8738_01572) vicX 1451747..1452556 (-) 810 WP_020917220.1 MBL fold metallo-hydrolase Regulator
  DQM48_RS07440 (NCTC8738_01573) vicK 1452557..1453909 (-) 1353 WP_020917221.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM48_RS07445 (NCTC8738_01574) vicR 1453902..1454612 (-) 711 WP_020917222.1 response regulator YycF Regulator
  DQM48_RS07450 (NCTC8738_01575) - 1454924..1455682 (+) 759 WP_020917223.1 amino acid ABC transporter ATP-binding protein -
  DQM48_RS07455 (NCTC8738_01576) - 1455699..1456511 (+) 813 WP_020917224.1 transporter substrate-binding domain-containing protein -
  DQM48_RS07460 (NCTC8738_01577) - 1456527..1457234 (+) 708 WP_020917225.1 amino acid ABC transporter permease -
  DQM48_RS07465 (NCTC8738_01578) - 1457247..1457894 (+) 648 WP_020917226.1 amino acid ABC transporter permease -
  DQM48_RS07470 (NCTC8738_01579) - 1457931..1458539 (-) 609 WP_058814133.1 TVP38/TMEM64 family protein -
  DQM48_RS07475 (NCTC8738_01580) - 1458751..1459053 (-) 303 WP_020917228.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27107.88 Da        Isoelectric Point: 4.6998

>NTDB_id=1137834 DQM48_RS07445 WP_020917222.1 1453902..1454612(-) (vicR) [Streptococcus lutetiensis strain NCTC8738]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAIAKFDEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASSSNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1137834 DQM48_RS07445 WP_020917222.1 1453902..1454612(-) (vicR) [Streptococcus lutetiensis strain NCTC8738]
ATGAAAAAAATTCTTATTGTTGATGATGAAAAACCAATTTCAGATATTATTAAATTTAATTTAACTAAAGAAGGTTATGA
AACTGTTACGGCTTTTGATGGTCGTGAAGCTATTGCTAAATTTGATGAAGAAAATCCTGATTTGATTATCTTGGATTTGA
TGTTGCCAGAATTGGATGGACTTGAAGTTGCAAAAGAAGTTCGTAAAACAAGTCATATTCCGATTATTATGCTTTCTGCT
AAAGATAGCGAATTCGATAAAGTTATCGGTCTTGAAATCGGTGCAGATGACTATGTTACAAAACCTTTCTCAAATCGTGA
ATTGTTAGCACGTGTCAAAGCACACCTTCGTCGTACTGAGAACATCGAATCAGCCGTCGCTGAGGAAAATGCTTCTTCAT
CAAATTCTGAAATTACCATCGGCGATTTGAAGATTTTGCCTGATGCCTTTGTTGCTCAAAAACGTGGTGAAGACATCGAA
TTAACACACCGTGAATTTGAATTACTTCATCACTTAGCTACTCACATGGGACAAGTGATGACGCGTGAATACCTTCTGGA
AACTGTTTGGGGTTATGATTACTTTGGTGATGTCCGCACAGTTGACGTTACCATTCGTCGTTTGCGTGAAAAAATCGAAG
ACACTCCGAGTCGTCCAGAATACATTTTGACACGTCGCGGTGTTGGATACTACATGAAGTCTTATGAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

77.778

99.153

0.771
  covR Streptococcus salivarius strain HSISS4

46.983

98.305

0.462
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.69

98.305

0.449
  scnR Streptococcus mutans UA159

36.864

100

0.369

Multiple sequence alignment