Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   DQM48_RS07440 Genome accession   NZ_LS483348
Coordinates   1452557..1453909 (-) Length   450 a.a.
NCBI ID   WP_020917221.1    Uniprot ID   A0AB38G6Z7
Organism   Streptococcus lutetiensis strain NCTC8738     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1447557..1458909
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM48_RS07430 (NCTC8738_01571) rnc 1450840..1451526 (-) 687 WP_020917219.1 ribonuclease III -
  DQM48_RS07435 (NCTC8738_01572) vicX 1451747..1452556 (-) 810 WP_020917220.1 MBL fold metallo-hydrolase Regulator
  DQM48_RS07440 (NCTC8738_01573) vicK 1452557..1453909 (-) 1353 WP_020917221.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM48_RS07445 (NCTC8738_01574) vicR 1453902..1454612 (-) 711 WP_020917222.1 response regulator YycF Regulator
  DQM48_RS07450 (NCTC8738_01575) - 1454924..1455682 (+) 759 WP_020917223.1 amino acid ABC transporter ATP-binding protein -
  DQM48_RS07455 (NCTC8738_01576) - 1455699..1456511 (+) 813 WP_020917224.1 transporter substrate-binding domain-containing protein -
  DQM48_RS07460 (NCTC8738_01577) - 1456527..1457234 (+) 708 WP_020917225.1 amino acid ABC transporter permease -
  DQM48_RS07465 (NCTC8738_01578) - 1457247..1457894 (+) 648 WP_020917226.1 amino acid ABC transporter permease -
  DQM48_RS07470 (NCTC8738_01579) - 1457931..1458539 (-) 609 WP_058814133.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51377.40 Da        Isoelectric Point: 4.8298

>NTDB_id=1137833 DQM48_RS07440 WP_020917221.1 1452557..1453909(-) (vicK) [Streptococcus lutetiensis strain NCTC8738]
MNDTMVKNQYLFEQAILFLLAFVAIYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQKQLNLEREEALGMNIVDILGDDSDYSYHDLVSKTPE
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWVEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDNED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1137833 DQM48_RS07440 WP_020917221.1 1452557..1453909(-) (vicK) [Streptococcus lutetiensis strain NCTC8738]
ATGAATGATACAATGGTAAAGAATCAATATCTGTTTGAACAAGCCATTCTCTTCTTGCTAGCTTTTGTAGCCATTTATTT
TATTCATTTGGCTATCAGAGACTATAGAACGTCTGTTAATATTCGTCGATTAAGTGGTAAGGTTCGTGAACTGATTACAG
GAAAATACACAGAAGATATTATCATTGAAAAAGACAGAGATTTAGCAGAGTTAGCTGGTCAGTTAAATGATTTGTCAACT
GTCTTTCGTTTAGCTCAAGAAAATCTAGCCCAAGAAAAGAATCGTTTGGCAAGTATTTTGTCTTACATGACTGATGGGGT
GCTAGCGACTGATCGTTCTGGAAATATCACCATGATTAACCAGACCGCTCAAAAGCAACTAAATCTTGAGCGTGAAGAAG
CTCTTGGGATGAATATCGTTGACATTCTTGGTGATGATAGCGATTATTCTTACCATGATTTGGTGTCTAAGACGCCAGAA
ATTGTGCTTAATCGTCGTGATGAGACGGGAGAATTTATCACTTTGCGTATTCGATTTGCCTTGAATCGTAGAGATAGTGG
ATTTATTTCTGGTCTGATTGCCGTCTTGCACGATACAACGGAACAAGAAAAAGAAGACCGCGAACGTCGCTTGTTCGTTT
CTAACGTTAGTCATGAGTTGCGTACGCCACTGACTTCGGTTAAATCTTATCTTGAAGCACTGGATGAAGGGGCTTTGAAA
GAAGATATTGCACCAAGTTTCATCAAAGTTTCTTTGGATGAAACCAATCGTATGATTCGCATGATTTCTGATTTGCTTAA
TCTGTCTCGAATCGACAATCAAACGGTGCAATTAGAAGTTGAAATGACTAACTTCACAGCCTTTATGACGTCTATTTTGA
ATCGTTTTGACCAGATTAAAAGTCAACACACGGTTGCTGGCAAGCAATACGAAATTGTCAGAGACTATCCAATCAAGTCA
ATCTGGGTTGAAATTGACCCAGATAAGATGACACAAGTCTTGGATAATATCCTAAACAATGCCATTAAGTACTCACCAGA
CGGTGGTAAAATCACTGTTAGCATGAAGACTACTGAAACTCAGTTGATTATTTCGATTTCTGATGAAGGACTTGGTATTC
CGAAGAAAGACTTGCCGTTAATCTTTGACCGTTTCTACCGTGTTGATAAGGCTAGAAGTCGTGCCCAAGGTGGTTCAGGG
CTTGGACTTGCCATTGCTAAAGAAATTGTCAAACAACATAAAGGATTTATTTGGGCTCAAAGTACCTATGGTAAGGGCTC
AACATTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGATGAATGGGAGGATAACGAGGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.867

92.222

0.709
  micB Streptococcus pneumoniae Cp1015

64.237

97.556

0.627

Multiple sequence alignment