Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQM48_RS00720 Genome accession   NZ_LS483348
Coordinates   107134..108177 (+) Length   347 a.a.
NCBI ID   WP_020915988.1    Uniprot ID   -
Organism   Streptococcus lutetiensis strain NCTC8738     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 102134..113177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM48_RS00710 (NCTC8738_00142) - 105829..106197 (+) 369 WP_020915986.1 DUF1033 family protein -
  DQM48_RS00715 (NCTC8738_00143) comYA 106269..107210 (+) 942 WP_020915987.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM48_RS00720 (NCTC8738_00144) comYB 107134..108177 (+) 1044 WP_020915988.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM48_RS00725 (NCTC8738_00145) comYC 108177..108470 (+) 294 WP_020915989.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM48_RS00730 (NCTC8738_00146) comYD 108454..108885 (+) 432 WP_020915990.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM48_RS00735 (NCTC8738_00147) comYE 108839..109132 (+) 294 WP_020915991.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM48_RS00740 (NCTC8738_00148) comYF 109116..109553 (+) 438 WP_043894883.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM48_RS00745 (NCTC8738_00149) comGG 109525..109938 (+) 414 WP_231872460.1 competence type IV pilus minor pilin ComGG -
  DQM48_RS00750 (NCTC8738_00150) comYH 109928..110884 (+) 957 WP_020915994.1 class I SAM-dependent methyltransferase Machinery gene
  DQM48_RS00755 (NCTC8738_00151) - 110938..112137 (+) 1200 WP_020915995.1 acetate kinase -
  DQM48_RS00760 (NCTC8738_00152) - 112297..112494 (+) 198 WP_020915996.1 helix-turn-helix transcriptional regulator -
  DQM48_RS00765 (NCTC8738_00153) - 112511..112711 (+) 201 WP_111699164.1 hypothetical protein -
  DQM48_RS00770 (NCTC8738_00154) - 112712..113167 (+) 456 WP_231853254.1 ABC transporter permease -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39552.77 Da        Isoelectric Point: 9.2096

>NTDB_id=1137797 DQM48_RS00720 WP_020915988.1 107134..108177(+) (comYB) [Streptococcus lutetiensis strain NCTC8738]
MSKLKALLGTDILALRKQKSKKLPFKKQQKVIQLFNNLFNSGFNLTEIVSFLRRSQLLAEVYVDSMQESLLSGASLADMM
AKLGFSDTIVTQIALADVHGNCQQSLLKIDGYLASMSVVRKKLIEVATYPLILFSFLILIMLGLKNYLLPQLENQNFATQ
IISHFPMIFLGGFALLALGILLGVLYAEHLSPIYLYSQLSRLPIFGRHVRLYLTAYYAREWGNLIGQGIELMEIVELMQR
QKSRLFQEIGKDMQEALLSGQSFHQKVLDYPFFLRELSLMIEYGEVKSKLGRELDIYAEETWQNFFSQLTQATQLIQPLV
FVFVASIIVLIYVAMLLPMYQNMGGNF

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=1137797 DQM48_RS00720 WP_020915988.1 107134..108177(+) (comYB) [Streptococcus lutetiensis strain NCTC8738]
ATGAGCAAATTAAAAGCCTTGCTAGGGACGGACATATTGGCCTTGAGGAAGCAAAAATCGAAAAAATTGCCCTTTAAAAA
ACAGCAGAAGGTGATTCAATTATTTAACAATCTCTTTAACAGCGGCTTTAATTTAACAGAAATTGTTTCTTTTTTGAGAC
GAAGTCAGTTGTTGGCGGAAGTTTATGTGGACAGTATGCAAGAGTCATTGTTAAGTGGGGCAAGTTTGGCAGATATGATG
GCTAAGCTGGGCTTTTCAGATACAATTGTCACCCAGATTGCTCTTGCGGATGTTCATGGGAATTGTCAGCAGAGTTTGTT
AAAAATTGATGGTTACTTGGCTAGTATGTCAGTTGTTCGAAAGAAATTGATTGAAGTGGCGACTTATCCTTTGATTTTGT
TTAGCTTTTTAATTCTGATTATGTTGGGCTTGAAAAATTATTTGCTGCCGCAGTTGGAAAATCAAAATTTTGCAACTCAG
ATTATCAGCCATTTTCCTATGATTTTTTTGGGTGGCTTTGCTCTTTTAGCTTTAGGAATTCTGCTTGGGGTTCTGTATGC
CGAGCACTTATCGCCAATTTATCTGTATAGTCAGTTAAGTCGTTTGCCAATATTTGGTCGGCACGTGCGCCTTTATTTGA
CGGCTTATTATGCGCGTGAGTGGGGAAATCTTATCGGACAAGGTATCGAACTGATGGAGATTGTAGAGCTTATGCAGCGG
CAAAAATCACGTCTCTTTCAGGAAATTGGAAAAGATATGCAGGAAGCTTTGTTGTCTGGTCAGTCTTTTCATCAGAAAGT
GCTGGATTACCCTTTCTTTTTGCGTGAACTTAGCTTAATGATTGAATATGGCGAGGTCAAGTCAAAATTAGGTCGTGAGT
TAGATATTTATGCCGAAGAGACTTGGCAGAATTTCTTTAGTCAATTGACGCAGGCAACGCAGCTAATTCAGCCTTTGGTC
TTTGTCTTTGTTGCTTCAATCATCGTTTTAATTTATGTGGCAATGCTTTTGCCGATGTATCAAAATATGGGAGGAAATTT
TTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

64.873

91.066

0.591
  comYB Streptococcus mutans UA159

64.873

91.066

0.591
  comYB Streptococcus gordonii str. Challis substr. CH1

57.941

97.983

0.568
  comGB/cglB Streptococcus mitis NCTC 12261

57.27

97.118

0.556
  comGB/cglB Streptococcus mitis SK321

56.38

97.118

0.548
  comGB/cglB Streptococcus pneumoniae Rx1

55.786

97.118

0.542
  comGB/cglB Streptococcus pneumoniae D39

55.786

97.118

0.542
  comGB/cglB Streptococcus pneumoniae R6

55.786

97.118

0.542
  comGB/cglB Streptococcus pneumoniae TIGR4

55.786

97.118

0.542
  comGB Lactococcus lactis subsp. cremoris KW2

51.19

96.83

0.496

Multiple sequence alignment