Detailed information NTG1137599

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL21_RS04725
• Genome accession: NZ_LS483343
• Coordinates: 912667..913509 (-)
• Length: 280 a.a.
• NCBI ID: WP_018029793.1
• Uniprot ID: -
• Organism: Streptococcus ferus strain NCTC12278
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 907667..918509

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL21_RS04715 (NCTC12278_00934)	trmFO	908857..910191 (-)	1335	WP_018029791.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
DQL21_RS04720 (NCTC12278_00935)	topA	910455..912572 (-)	2118	WP_018029792.1	type I DNA topoisomerase	-
DQL21_RS04725 (NCTC12278_00936)	dprA	912667..913509 (-)	843	WP_018029793.1	DNA-processing protein DprA	Machinery gene
DQL21_RS04730 (NCTC12278_00937)	-	913558..914505 (-)	948	WP_018029794.1	ROK family protein	-
DQL21_RS04735 (NCTC12278_00938)	-	914520..915068 (-)	549	WP_018029795.1	sugar O-acetyltransferase	-
DQL21_RS04740 (NCTC12278_00939)	-	915095..915862 (-)	768	WP_018029796.1	ribonuclease HII	-
DQL21_RS04745 (NCTC12278_00940)	ylqF	915849..916700 (-)	852	WP_018029797.1	ribosome biogenesis GTPase YlqF	-
DQL21_RS04750 (NCTC12278_00941)	-	916818..917156 (-)	339	WP_018029798.1	ATP cone domain-containing protein	-
DQL21_RS04755 (NCTC12278_00942)	-	917287..917790 (-)	504	WP_018029799.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31063.88 Da
• Isoelectric Point: 8.6688

>NTDB_id=1137599 DQL21_RS04725 WP_018029793.1 912667..913509(-) (dprA) [Streptococcus ferus strain NCTC12278]
MNHFDIYKLKKAGLNNLNVINILNYQEKHQKSLSLRDIAVVSDCKNPLQFIENYKNLDSKTLRKEFTKFPSLSILDKEYP
LSLKEIYNPPVLLFYQGDLSLLEKPKLAVVGSRDASSVGSKSVQKIINELNKRFVIVSGLARGIDTAAHLAALKNGGSTI
AVIGCGLDTYYPKENQKLQDYIGKHHLILSEYGPQSQPLKFHFPERNRIIAGLCQGIMVAEAKMRSGSLITCERGMEEGR
DVFAVPGSILDGKSDGCHHLIQEGAKCVTSGFDIVSELLN

Nucleotide

• Length: 843 bp

>NTDB_id=1137599 DQL21_RS04725 WP_018029793.1 912667..913509(-) (dprA) [Streptococcus ferus strain NCTC12278]
ATGAATCATTTCGACATCTATAAATTAAAGAAAGCGGGCTTAAATAACCTCAATGTTATTAATATCCTCAATTATCAGGA
AAAACATCAAAAATCCTTATCTCTTAGAGATATAGCCGTGGTCTCAGACTGCAAAAATCCTTTGCAATTCATTGAAAACT
ATAAAAATTTAGACAGCAAAACACTTAGGAAGGAATTTACCAAATTCCCCTCCCTATCTATTTTAGATAAAGAATATCCC
TTATCTTTAAAGGAAATCTATAACCCTCCTGTTCTTTTGTTTTACCAAGGAGATCTCAGTCTATTGGAAAAACCTAAATT
AGCAGTTGTAGGTTCGCGCGATGCTAGCTCAGTCGGCAGTAAGTCTGTTCAGAAGATTATCAATGAATTAAACAAACGGT
TTGTCATTGTAAGCGGTCTAGCTAGAGGTATTGATACCGCCGCTCATTTAGCAGCTTTAAAAAACGGTGGCTCCACAATA
GCCGTCATCGGATGCGGATTGGACACGTATTACCCCAAAGAAAATCAGAAGCTCCAGGACTATATTGGGAAGCATCACCT
GATTTTATCCGAATACGGCCCCCAAAGTCAGCCCTTAAAATTCCATTTTCCAGAAAGAAATCGCATTATCGCAGGTTTAT
GTCAGGGAATTATGGTAGCCGAAGCTAAGATGCGTTCTGGAAGTCTGATTACCTGTGAAAGAGGGATGGAAGAAGGACGA
GATGTTTTCGCCGTACCAGGCTCTATTTTAGACGGTAAATCTGATGGCTGCCATCATCTCATTCAAGAGGGGGCAAAGTG
CGTCACAAGTGGGTTCGACATTGTTTCAGAACTCTTAAATTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (72-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	76.259	99.286	0.757
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	66.906	99.286	0.664
dprA/cilB/dalA	Streptococcus pneumoniae D39	66.547	99.286	0.661
dprA/cilB/dalA	Streptococcus pneumoniae R6	66.547	99.286	0.661
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	66.547	99.286	0.661
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	66.547	99.286	0.661
dprA/cilB/dalA	Streptococcus mitis SK321	66.187	99.286	0.657
dprA	Lactococcus lactis subsp. cremoris KW2	59.14	99.643	0.589
dprA	Legionella pneumophila strain ERS1305867	44.77	85.357	0.382
dprA	Latilactobacillus sakei subsp. sakei 23K	38.095	97.5	0.371
dprA	Bacillus subtilis subsp. subtilis str. 168	48.095	75	0.361