Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   DQL23_RS10490 Genome accession   NZ_LS483341
Coordinates   2149915..2152068 (-) Length   717 a.a.
NCBI ID   WP_060554271.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC7865     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2144915..2157068
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL23_RS10475 (NCTC7865_02113) purD 2145278..2146537 (-) 1260 WP_060554268.1 phosphoribosylamine--glycine ligase -
  DQL23_RS10480 (NCTC7865_02114) lytF 2146781..2148430 (+) 1650 WP_060554269.1 GBS Bsp-like repeat-containing protein Regulator
  DQL23_RS10485 (NCTC7865_02115) comB 2148547..2149905 (-) 1359 WP_060554270.1 competence pheromone export protein ComB Regulator
  DQL23_RS10490 (NCTC7865_02116) comA 2149915..2152068 (-) 2154 WP_060554271.1 peptide cleavage/export ABC transporter ComA Regulator
  DQL23_RS10500 (NCTC7865_02117) rpsD 2152523..2153134 (-) 612 WP_008810013.1 30S ribosomal protein S4 -
  DQL23_RS10505 (NCTC7865_02118) - 2153400..2154122 (-) 723 WP_045504753.1 ABC transporter ATP-binding protein -
  DQL23_RS10510 (NCTC7865_02119) - 2154122..2155123 (-) 1002 WP_111705914.1 ABC transporter substrate-binding protein -
  DQL23_RS10515 (NCTC7865_02120) - 2155165..2155917 (-) 753 WP_060554273.1 ABC transporter permease -
  DQL23_RS10520 (NCTC7865_02121) - 2155880..2156170 (-) 291 WP_060554280.1 thiamine-binding protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80699.73 Da        Isoelectric Point: 6.9125

>NTDB_id=1137511 DQL23_RS10490 WP_060554271.1 2149915..2152068(-) (comA) [Streptococcus gordonii strain NCTC7865]
MKFRKRHYRAQVDTRDCGVAALAMVFGYYGSYFSLATLREKAKTTNDGTTALGLVKVAEGLNFETRAFKADMGIFDLEDV
SYPFIVHVLKEGKLLHYYVVMGQDKHTIHIADPDPQVKMTKISRERFEQEWTGITIFLAPSPAYKPSQEKKNGLLDFIPL
LIKQKGLITNIVLATLLVTVINIVGSYYLQSIIDTYVPDHMKTTLGMISIGLIIVYILQQFLSYAQEYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEIVSRFTDANRIIDALASTILSIFLDVSIVSIIAIVLFSQNSSLFFLTLLGIPVYAL
IIFLFMKPFEKMNHETMEANSLLSSSIIEDINGIETIKSLTSEKQRYQKIDKEFVTYLKKSFAYGRSESLQKVLKAAARL
ILNVLILWLGATLVMDQKISLGQLITYNTLLVYFTNPLENIINLQTKLQSARVANERLNEVYLVQSEFEEEKLIKDLSHF
QADIDFRGVSYKYGYGANVLSEIDLHIPAGSKTSFVGVSGSGKTTLAKMMVHFYGPNQGDICLGGVNLNQLDKQALRQYI
NYLPQQPYVFNGTILENLLLGAREGTTQEDILRAVELAEIRSDIERMPLNYQTELSADGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIIDNLMALDKTIIFIAHRLTIAERSEQVVVLDQGRIVESGSHKELIEKEGFYHHLINS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=1137511 DQL23_RS10490 WP_060554271.1 2149915..2152068(-) (comA) [Streptococcus gordonii strain NCTC7865]
ATGAAATTTAGGAAACGGCATTACAGAGCGCAAGTTGATACTAGGGATTGCGGTGTGGCAGCTCTGGCTATGGTTTTTGG
TTATTATGGATCGTATTTTTCCTTGGCTACACTACGAGAAAAGGCAAAAACAACTAATGATGGCACAACTGCTTTGGGTT
TGGTGAAAGTTGCTGAGGGCTTAAATTTTGAGACAAGGGCTTTTAAAGCTGATATGGGAATCTTTGATCTGGAAGATGTA
TCTTATCCCTTCATCGTTCATGTACTTAAGGAAGGGAAACTCCTACATTATTATGTTGTAATGGGACAAGATAAACACAC
GATTCATATTGCAGACCCAGATCCTCAAGTTAAGATGACAAAGATTTCGCGAGAGCGTTTCGAACAGGAGTGGACAGGAA
TTACCATTTTCCTAGCTCCTAGTCCAGCCTATAAACCTAGTCAGGAAAAGAAAAATGGACTTTTAGACTTCATTCCCTTA
TTGATTAAACAGAAGGGATTGATTACTAATATTGTGCTTGCAACTTTGCTGGTAACGGTGATCAATATTGTTGGATCCTA
CTACCTTCAGTCGATTATTGATACTTATGTGCCTGATCATATGAAAACGACGCTGGGTATGATTTCTATCGGCTTGATTA
TTGTCTATATTTTGCAGCAATTCTTGTCTTATGCCCAAGAATATTTGCTTTTGGTTTTAGGGCAACGCCTATCAATTGAT
GTGATCTTATCCTATATCAAGCACGTTTTTCAGCTACCTATGTCATTTTTCGCGACAAGGCGGACAGGGGAAATTGTCTC
TCGTTTTACGGATGCCAATCGGATTATTGATGCCTTGGCCAGTACAATCTTGTCTATTTTCTTGGATGTGTCAATTGTGT
CGATCATTGCGATTGTTCTTTTTTCACAAAATAGCAGTCTTTTCTTTTTGACCTTGCTAGGAATCCCCGTTTACGCGCTC
ATTATTTTTCTTTTTATGAAGCCTTTTGAAAAGATGAATCATGAGACGATGGAAGCAAATAGTCTGTTGTCGTCTTCCAT
TATTGAAGATATCAATGGAATTGAGACCATTAAGTCTTTGACCAGCGAAAAACAACGTTATCAGAAGATTGACAAGGAAT
TTGTGACTTATCTGAAAAAGTCTTTTGCATATGGACGTTCTGAGAGTTTACAAAAAGTCTTGAAAGCAGCAGCTCGTTTG
ATTTTAAACGTCTTGATTTTATGGCTAGGAGCCACACTTGTCATGGATCAAAAAATCAGTCTGGGACAGCTCATCACTTA
TAATACACTTCTAGTCTACTTTACTAATCCTTTGGAAAATATCATCAATCTGCAAACGAAGTTACAGTCTGCACGAGTGG
CCAATGAGCGTCTCAATGAGGTCTATTTAGTCCAGTCTGAATTTGAAGAAGAGAAGCTTATCAAGGACTTGAGCCACTTT
CAGGCTGACATCGATTTTCGTGGAGTCAGTTATAAGTATGGCTATGGGGCCAATGTATTATCGGAAATTGACTTGCATAT
TCCTGCTGGAAGTAAGACCAGCTTTGTTGGTGTATCCGGCTCAGGAAAAACGACCTTGGCCAAGATGATGGTGCATTTTT
ATGGTCCGAATCAAGGGGATATTTGTCTGGGAGGTGTCAATCTCAATCAGCTGGATAAGCAGGCACTGCGCCAATATATC
AACTATCTTCCCCAGCAACCGTATGTTTTTAATGGGACTATTTTGGAAAATTTACTCTTAGGCGCGCGTGAAGGCACGAC
TCAAGAAGATATTCTGCGGGCGGTAGAATTGGCAGAAATTAGGTCGGATATTGAGCGGATGCCTCTCAATTATCAGACAG
AGCTATCAGCAGATGGAGCAGGGATTTCAGGTGGTCAACGCCAGCGTATTGCTCTAGCGAGGGCTCTCTTGACAGATGCG
CCAGTGCTTATCTTAGATGAAGCAACAAGCAGTCTGGATATTTTGACGGAGAAGCGGATCATTGATAATTTGATGGCGCT
TGATAAGACGATTATTTTTATTGCTCATCGTTTGACTATTGCGGAACGTTCGGAGCAGGTGGTCGTTTTGGATCAAGGTA
GGATTGTTGAGAGTGGAAGTCATAAGGAGCTGATAGAAAAAGAAGGCTTTTACCACCATTTGATCAATAGTTAG

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter transmembrane region (ABC_membrane)

(170-438)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

97.768

100

0.978
  comA Streptococcus pneumoniae Rx1

80.893

100

0.809
  comA Streptococcus pneumoniae D39

80.893

100

0.809
  comA Streptococcus pneumoniae R6

80.893

100

0.809
  comA Streptococcus mitis NCTC 12261

80.753

100

0.808
  comA Streptococcus mitis SK321

80.614

100

0.806
  comA Streptococcus pneumoniae TIGR4

80.474

100

0.805
  comA/nlmT Streptococcus mutans UA159

64.993

100

0.65

Multiple sequence alignment