Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   DQL23_RS10485 Genome accession   NZ_LS483341
Coordinates   2148547..2149905 (-) Length   452 a.a.
NCBI ID   WP_060554270.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC7865     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2143547..2154905
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL23_RS10470 (NCTC7865_02112) - 2144030..2145223 (-) 1194 WP_045504743.1 ATP-grasp domain-containing protein -
  DQL23_RS10475 (NCTC7865_02113) purD 2145278..2146537 (-) 1260 WP_060554268.1 phosphoribosylamine--glycine ligase -
  DQL23_RS10480 (NCTC7865_02114) lytF 2146781..2148430 (+) 1650 WP_060554269.1 GBS Bsp-like repeat-containing protein Regulator
  DQL23_RS10485 (NCTC7865_02115) comB 2148547..2149905 (-) 1359 WP_060554270.1 competence pheromone export protein ComB Regulator
  DQL23_RS10490 (NCTC7865_02116) comA 2149915..2152068 (-) 2154 WP_060554271.1 peptide cleavage/export ABC transporter ComA Regulator
  DQL23_RS10500 (NCTC7865_02117) rpsD 2152523..2153134 (-) 612 WP_008810013.1 30S ribosomal protein S4 -
  DQL23_RS10505 (NCTC7865_02118) - 2153400..2154122 (-) 723 WP_045504753.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 49812.04 Da        Isoelectric Point: 5.9046

>NTDB_id=1137510 DQL23_RS10485 WP_060554270.1 2148547..2149905(-) (comB) [Streptococcus gordonii strain NCTC7865]
MNEQFLESAEFYQKRYHNFASCLIVPSLILLVFLVGFSMLAKKEITISSRASVEASRVLAQIQSTSNQPIIANHLSENKE
VKKGDLLIQYAVEGEGAQEQKFSSQLDLLKDQKGKLETLRSSLESGRNQFTEPDSYGYEQSFKDYQNQVASMTSSVNQQN
ATIASQNAAASQSQAELGGVISDVDSKLNDYRNLKNAIQSGVGIDASQPLYSLYQSYRDQLSSAEDKATAQSQIVAQLDG
QISQLEATAATYRVQYAGAGAQQAYASNLSSQLASLKAQYLVKVGQELTTLTQQILEAESNLKLQETVSKRGQILAEMDG
LLHLNPEVQGSTLVAEGTALAQIYPKITSERKIKIVTYVSSKDVSTIKNGDKVRFITADDANKQMILTSQISSIDANATQ
TKQGNFFKVECEMAVSKDQAKKLRYGLEGKFVMVTGQKTYFSYYMEKFFNLG

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=1137510 DQL23_RS10485 WP_060554270.1 2148547..2149905(-) (comB) [Streptococcus gordonii strain NCTC7865]
ATGAATGAACAGTTTTTAGAAAGTGCAGAGTTTTATCAGAAACGTTATCATAATTTTGCTAGTTGTTTAATTGTGCCAAG
TCTTATTTTACTAGTATTTCTAGTTGGTTTTTCCATGCTGGCTAAAAAGGAAATTACGATTTCTAGCCGTGCTTCTGTAG
AAGCTAGCCGAGTACTGGCTCAGATTCAGTCAACTAGTAACCAGCCTATCATTGCGAATCATTTGTCAGAAAACAAGGAG
GTCAAAAAAGGGGACCTGCTAATCCAGTATGCAGTAGAAGGAGAGGGGGCTCAGGAACAGAAGTTTTCCAGCCAGCTTGA
CTTACTCAAAGATCAAAAGGGCAAACTAGAAACTTTGCGTTCCAGTTTAGAAAGCGGGCGTAATCAATTCACTGAGCCAG
ATAGTTATGGCTATGAACAAAGCTTTAAAGACTACCAGAATCAAGTAGCGAGTATGACTAGTTCTGTGAATCAGCAAAAT
GCTACGATTGCTTCACAAAATGCAGCGGCCAGTCAGTCTCAGGCGGAACTGGGCGGTGTTATCAGTGATGTGGATAGCAA
ACTAAATGACTATCGAAACTTGAAAAATGCCATTCAAAGTGGGGTGGGTATAGATGCATCGCAACCTCTTTACTCCTTGT
ATCAGTCCTATCGTGATCAGTTGAGTTCGGCAGAGGATAAGGCAACAGCTCAAAGTCAGATTGTAGCTCAATTAGATGGG
CAAATCTCTCAATTAGAAGCAACAGCTGCGACTTATCGTGTCCAATATGCTGGTGCAGGCGCCCAACAAGCCTATGCTAG
CAATTTATCCAGTCAGTTGGCTTCACTGAAAGCCCAGTATCTGGTCAAGGTAGGACAAGAATTGACCACTCTGACTCAGC
AAATCTTGGAAGCCGAGAGCAATCTTAAACTTCAAGAAACAGTCTCTAAGCGAGGTCAGATTTTGGCTGAAATGGATGGC
TTGCTTCACTTAAATCCAGAAGTGCAAGGATCTACTCTGGTGGCAGAAGGAACAGCTTTGGCTCAGATTTATCCTAAAAT
CACCAGTGAACGAAAAATCAAAATTGTCACATATGTCTCTTCCAAGGATGTATCTACTATTAAAAATGGAGACAAGGTGC
GCTTTATCACTGCTGATGACGCTAACAAACAAATGATTTTGACATCCCAAATTTCCAGTATTGACGCCAATGCTACCCAA
ACCAAACAGGGGAATTTCTTTAAAGTAGAATGCGAAATGGCTGTTAGTAAAGATCAAGCTAAGAAGCTCCGCTATGGCTT
GGAAGGTAAATTCGTCATGGTAACTGGGCAAAAGACTTATTTCAGCTATTATATGGAGAAGTTTTTTAATCTTGGTTGA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(314-426)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

98.009

100

0.98
  comB Streptococcus pneumoniae Rx1

56.222

99.558

0.56
  comB Streptococcus pneumoniae D39

56.222

99.558

0.56
  comB Streptococcus pneumoniae R6

56.222

99.558

0.56
  comB Streptococcus mitis NCTC 12261

56

99.558

0.558
  comB Streptococcus pneumoniae TIGR4

55.778

99.558

0.555
  comB Streptococcus mitis SK321

55.333

99.558

0.551

Multiple sequence alignment