Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   DQL34_RS00365 Genome accession   NZ_LS483339
Coordinates   61041..61229 (+) Length   62 a.a.
NCBI ID   WP_111679075.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain NCTC12958     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 53604..62299 61041..61229 within 0


Gene organization within MGE regions


Location: 53604..62299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL34_RS00305 (NCTC12958_00065) - 53604..54770 (-) 1167 WP_111679066.1 tyrosine-type recombinase/integrase -
  DQL34_RS11700 (NCTC12958_00066) - 54912..55493 (-) 582 WP_084828737.1 helix-turn-helix domain-containing protein -
  DQL34_RS00315 (NCTC12958_00067) - 55643..55813 (+) 171 WP_084829211.1 helix-turn-helix transcriptional regulator -
  DQL34_RS00320 (NCTC12958_00068) - 56066..56359 (+) 294 WP_111679067.1 hypothetical protein -
  DQL34_RS00325 (NCTC12958_00069) - 56363..56557 (+) 195 WP_024704077.1 hypothetical protein -
  DQL34_RS00330 (NCTC12958_00070) - 56571..56807 (+) 237 WP_024704076.1 hypothetical protein -
  DQL34_RS00340 (NCTC12958_00072) - 57143..57415 (+) 273 WP_023909303.1 MerR family transcriptional regulator -
  DQL34_RS00345 (NCTC12958_00073) - 57430..58290 (+) 861 WP_111679069.1 primase alpha helix C-terminal domain-containing protein -
  DQL34_RS00350 (NCTC12958_00074) - 58280..59785 (+) 1506 WP_111679071.1 phage/plasmid primase, P4 family -
  DQL34_RS00355 (NCTC12958_00076) - 60082..60267 (+) 186 WP_111679073.1 hypothetical protein -
  DQL34_RS00360 (NCTC12958_00077) - 60333..60560 (+) 228 WP_223899748.1 hypothetical protein -
  DQL34_RS00365 (NCTC12958_00078) prx 61041..61229 (+) 189 WP_111679075.1 hypothetical protein Regulator
  DQL34_RS00370 (NCTC12958_00079) - 61610..62299 (+) 690 WP_197709066.1 DUF3800 domain-containing protein -

Sequence


Protein


Download         Length: 62 a.a.        Molecular weight: 7133.08 Da        Isoelectric Point: 4.5837

>NTDB_id=1137333 DQL34_RS00365 WP_111679075.1 61041..61229(+) (prx) [Streptococcus thermophilus strain NCTC12958]
MLTYDEFKEAMDNGFIKGDTVQIVRKNGKIHDYVLDGERVEPHEILRLEKVSDIIKELGGDN

Nucleotide


Download         Length: 189 bp        

>NTDB_id=1137333 DQL34_RS00365 WP_111679075.1 61041..61229(+) (prx) [Streptococcus thermophilus strain NCTC12958]
ATGCTAACCTATGATGAATTTAAAGAGGCAATGGACAATGGTTTTATTAAAGGTGATACTGTCCAGATTGTCCGAAAGAA
TGGTAAGATCCATGACTACGTTTTAGACGGTGAACGAGTTGAGCCACACGAAATATTGAGATTAGAAAAAGTATCGGATA
TAATAAAAGAACTAGGCGGAGACAACTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

60.345

93.548

0.565

  prx Streptococcus pyogenes MGAS8232

59.322

95.161

0.565

  prx Streptococcus pyogenes MGAS315

57.627

95.161

0.548

  prx Streptococcus pyogenes MGAS315

56.897

93.548

0.532

  prx Streptococcus pyogenes MGAS315

74.419

69.355

0.516

  prx Streptococcus pyogenes MGAS315

65.957

75.806

0.5

  prx Streptococcus pyogenes MGAS315

65.957

75.806

0.5


Multiple sequence alignment