Detailed information NTG1136547

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: DQL35_RS00280
• Genome accession: NZ_LS483325
• Coordinates: 47958..48872 (+)
• Length: 304 a.a.
• NCBI ID: WP_111677624.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC7022
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 42958..53872

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL35_RS00260 (NCTC7022_00052)	purE	44115..44603 (+)	489	WP_111677621.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
DQL35_RS00265 (NCTC7022_00053)	purK	44590..45681 (+)	1092	WP_111677622.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
DQL35_RS00270 (NCTC7022_00054)	-	45691..45915 (+)	225	WP_111677623.1	phosphoribosylaminoimidazole carboxylase	-
DQL35_RS00275 (NCTC7022_00056)	purB	46369..47661 (+)	1293	WP_037582405.1	adenylosuccinate lyase	-
DQL35_RS00280 (NCTC7022_00057)	comR	47958..48872 (+)	915	WP_111677624.1	helix-turn-helix domain-containing protein	Regulator
DQL35_RS10990 (NCTC7022_00058)	comS	48955..49053 (+)	99	WP_200831644.1	quorum-sensing system DWW-type pheromone	Regulator
DQL35_RS00285 (NCTC7022_00059)	ruvB	49087..50088 (+)	1002	WP_111677625.1	Holliday junction branch migration DNA helicase RuvB	-
DQL35_RS00290 (NCTC7022_00060)	-	50381..50839 (+)	459	WP_111677626.1	low molecular weight protein-tyrosine-phosphatase	-
DQL35_RS00295 (NCTC7022_00061)	-	50845..51246 (+)	402	WP_037582396.1	membrane protein	-
DQL35_RS00300 (NCTC7022_00062)	-	51243..53024 (+)	1782	WP_037582394.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35851.33 Da
• Isoelectric Point: 4.4139

>NTDB_id=1136547 DQL35_RS00280 WP_111677624.1 47958..48872(+) (comR) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKLEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDVEMAEKCYDKACLFAQLTGDQYLEKKLREEWDKDIKQYQ

Nucleotide

• Length: 915 bp

>NTDB_id=1136547 DQL35_RS00280 WP_111677624.1 47958..48872(+) (comR) [Streptococcus equi subsp. zooepidemicus strain NCTC7022]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTTCGGTATCAGAAAAAAATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTGGCACGAATAGAACTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTTTATTG
CTAAGGCTTTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTACCTAAGCGCTATAAGGAGCTTAAA
TATTTGATTTTAAGAACACCGACCTATATGGACGATGACAAATTAAAGCTACGTGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGATCAGCTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACTG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAGACAAAAAGCAAGACTCAATTTAGAGAGAATGAC
CTTATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAACAATAAGCTGGAGATTCTTGAGAAGGTTATTGTGCTTAGTCAAAAAATTATTCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATACGCTTTAATGAAGAAAAAAGACGTAGA
AATGGCAGAAAAATGTTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTAGAAAAGAAATTAAGAG
AAGAATGGGATAAAGATATAAAACAATATCAATAG

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix domain (HTH_19) (6-69)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.917	99.671	0.747
comR	Streptococcus pyogenes MGAS315	54.485	99.013	0.539
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.069	95.395	0.497
comR	Streptococcus mutans UA159	48.829	98.355	0.48
comR	Streptococcus suis P1/7	38.591	98.026	0.378
comR	Streptococcus suis 05ZYH33	38.644	97.039	0.375
comR	Streptococcus suis D9	37.037	97.697	0.362