Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   DQL15_RS04045 Genome accession   NZ_LS483323
Coordinates   796562..797236 (+) Length   224 a.a.
NCBI ID   WP_111689237.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8300     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 791562..802236
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL15_RS04025 (NCTC8300_00800) pstB 791995..792753 (+) 759 WP_002989690.1 phosphate ABC transporter ATP-binding protein PstB -
  DQL15_RS04030 (NCTC8300_00801) phoU 792821..793474 (+) 654 WP_002984514.1 phosphate signaling complex protein PhoU -
  DQL15_RS04040 (NCTC8300_00802) - 793679..796216 (+) 2538 WP_002989692.1 M1 family metallopeptidase -
  DQL15_RS04045 (NCTC8300_00803) ciaR 796562..797236 (+) 675 WP_111689237.1 response regulator transcription factor Regulator
  DQL15_RS04050 (NCTC8300_00804) ciaH 797229..798539 (+) 1311 WP_002989693.1 sensor histidine kinase Regulator
  DQL15_RS04055 (NCTC8300_00805) rpsT 798664..798912 (-) 249 WP_009881183.1 30S ribosomal protein S20 -
  DQL15_RS04060 (NCTC8300_00806) coaA 798966..799886 (-) 921 WP_002989697.1 type I pantothenate kinase -
  DQL15_RS04065 (NCTC8300_00807) - 800154..800747 (+) 594 WP_002989699.1 class I SAM-dependent methyltransferase -
  DQL15_RS04070 (NCTC8300_00808) - 801398..801787 (+) 390 WP_002984531.1 cytidine deaminase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25702.92 Da        Isoelectric Point: 4.8101

>NTDB_id=1136479 DQL15_RS04045 WP_111689237.1 796562..797236(+) (ciaR) [Streptococcus pyogenes strain NCTC8300]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFNGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFADKNISFGNLVVDLARKEVKVEGKVVELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYISKIRKKLKGTRFVNRLQTLRSVGYILKNNE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1136479 DQL15_RS04045 WP_111689237.1 796562..797236(+) (ciaR) [Streptococcus pyogenes strain NCTC8300]
ATGATAAAAATATTATTAGTAGAAGATGACTTGAGCTTATCAAATTCCATTTTTGATTTTTTAGATGATTTTGCAGACGT
CATGCAAGTTTTTAATGGCGATGAAGGTTTATACGAAGCAGAAAGTGGTATTTATGATTTGATTTTGTTAGACCTTATGT
TGCCGGAGAAAAATGGCTTTCAAGTCTTAAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGTTGATCATGACAGCT
AAAGAGGGTTTAGATGATAAAGGTCACGGATTTGAATTAGGTGCTGATGATTATCTGACCAAGCCGTTCTATTTAGAAGA
GTTAAAAATGCGAATTCAAGCACTGTTAAAAAGAACAGGGAAATTTGCAGATAAAAATATTAGTTTTGGCAATTTAGTGG
TTGACTTAGCTCGAAAAGAGGTGAAGGTTGAAGGGAAAGTAGTTGAATTACTTGGCAAAGAATTTGATTTGTTGGTGTAT
CTTTTGCAAAATCAAAACGTTATTTTACCAAAGACACAAATTTTTGATCGTTTATGGGGATTCGATAGTGATACTACGAT
TTCGGTTGTTGAAGTTTACATTTCTAAAATAAGAAAAAAATTAAAAGGTACCCGTTTTGTTAACAGGCTTCAAACTTTAA
GAAGCGTAGGGTATATTCTAAAAAACAATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

84.685

99.107

0.839
  ciaR Streptococcus pneumoniae D39

84.234

99.107

0.835
  ciaR Streptococcus pneumoniae R6

84.234

99.107

0.835
  ciaR Streptococcus pneumoniae TIGR4

84.234

99.107

0.835
  ciaR Streptococcus pneumoniae Rx1

84.234

99.107

0.835
  covR Lactococcus lactis subsp. lactis strain DGCC12653

39.111

100

0.393
  micA Streptococcus pneumoniae Cp1015

35.897

100

0.375
  covR Streptococcus salivarius strain HSISS4

36.726

100

0.371
  vicR Streptococcus mutans UA159

35.47

100

0.371

Multiple sequence alignment