Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DQM44_RS02995 Genome accession   NZ_LS483318
Coordinates   536302..537012 (+) Length   236 a.a.
NCBI ID   WP_012766682.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 531302..542012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM44_RS02970 (NCTC5370_00614) - 531982..532977 (+) 996 WP_003057220.1 DUF3114 domain-containing protein -
  DQM44_RS02975 (NCTC5370_00615) - 533073..533720 (-) 648 WP_003057245.1 amino acid ABC transporter permease -
  DQM44_RS02980 (NCTC5370_00616) - 533735..534436 (-) 702 WP_022554363.1 amino acid ABC transporter permease -
  DQM44_RS02985 (NCTC5370_00617) - 534450..535250 (-) 801 WP_022554364.1 transporter substrate-binding domain-containing protein -
  DQM44_RS02990 (NCTC5370_00618) - 535250..536043 (-) 794 Protein_539 amino acid ABC transporter ATP-binding protein -
  DQM44_RS02995 (NCTC5370_00619) vicR 536302..537012 (+) 711 WP_012766682.1 response regulator YycF Regulator
  DQM44_RS03000 (NCTC5370_00620) vicK 537005..538357 (+) 1353 WP_022554366.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM44_RS03005 (NCTC5370_00621) vicX 538361..539170 (+) 810 WP_046166040.1 MBL fold metallo-hydrolase Regulator
  DQM44_RS03010 (NCTC5370_00622) rnc 539928..540620 (+) 693 WP_003057240.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27057.95 Da        Isoelectric Point: 5.0023

>NTDB_id=1136194 DQM44_RS02995 WP_012766682.1 536302..537012(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1136194 DQM44_RS02995 WP_012766682.1 536302..537012(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGTCTTGAAATTGGGGCAGATGATTATGTTACCAAACCCTTTTCAAATCGTGA
ACTATTAGCTCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGTCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

79.487

99.153

0.788
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  scnR Streptococcus mutans UA159

37.712

100

0.377

Multiple sequence alignment