Detailed information NTG1136195

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: DQM44_RS03000
• Genome accession: NZ_LS483318
• Coordinates: 537005..538357 (+)
• Length: 450 a.a.
• NCBI ID: WP_022554366.1
• Uniprot ID: A0A9X8T4M5
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 532005..543357

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM44_RS02975 (NCTC5370_00615)	-	533073..533720 (-)	648	WP_003057245.1	amino acid ABC transporter permease	-
DQM44_RS02980 (NCTC5370_00616)	-	533735..534436 (-)	702	WP_022554363.1	amino acid ABC transporter permease	-
DQM44_RS02985 (NCTC5370_00617)	-	534450..535250 (-)	801	WP_022554364.1	transporter substrate-binding domain-containing protein	-
DQM44_RS02990 (NCTC5370_00618)	-	535250..536043 (-)	794	Protein_539	amino acid ABC transporter ATP-binding protein	-
DQM44_RS02995 (NCTC5370_00619)	vicR	536302..537012 (+)	711	WP_012766682.1	response regulator YycF	Regulator
DQM44_RS03000 (NCTC5370_00620)	vicK	537005..538357 (+)	1353	WP_022554366.1	cell wall metabolism sensor histidine kinase VicK	Regulator
DQM44_RS03005 (NCTC5370_00621)	vicX	538361..539170 (+)	810	WP_046166040.1	MBL fold metallo-hydrolase	Regulator
DQM44_RS03010 (NCTC5370_00622)	rnc	539928..540620 (+)	693	WP_003057240.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51476.06 Da
• Isoelectric Point: 5.7411

>NTDB_id=1136195 DQM44_RS03000 WP_022554366.1 537005..538357(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=1136195 DQM44_RS03000 WP_022554366.1 537005..538357(+) (vicK) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTACGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCTCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAAGCTCTTGATGAAGGTGCACTTAAA
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACTAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-165)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.43	92	0.676
micB	Streptococcus pneumoniae Cp1015	66.824	94.444	0.631