Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   DQM39_RS08555 Genome accession   NZ_LS483298
Coordinates   1628145..1628696 (-) Length   183 a.a.
NCBI ID   WP_079993350.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8225     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1623145..1633696
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM39_RS08520 (NCTC8225_01710) - 1623148..1623891 (-) 744 WP_172450333.1 class I SAM-dependent DNA methyltransferase -
  DQM39_RS08525 (NCTC8225_01711) rsfS 1623939..1624292 (-) 354 WP_011017339.1 ribosome silencing factor -
  DQM39_RS08530 (NCTC8225_01712) yqeK 1624316..1624909 (-) 594 WP_002985989.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  DQM39_RS08535 (NCTC8225_01713) - 1624906..1625538 (-) 633 WP_002991091.1 nicotinate-nucleotide adenylyltransferase -
  DQM39_RS08540 (NCTC8225_01714) yhbY 1625607..1625915 (-) 309 WP_002991094.1 ribosome assembly RNA-binding protein YhbY -
  DQM39_RS08545 (NCTC8225_01715) yqeH 1625941..1627059 (-) 1119 WP_002985994.1 ribosome biogenesis GTPase YqeH -
  DQM39_RS08550 (NCTC8225_01716) - 1627059..1627586 (-) 528 WP_002991099.1 YqeG family HAD IIIA-type phosphatase -
  DQM39_RS08555 (NCTC8225_01717) comX/sigX/comX2/sigX2 1628145..1628696 (-) 552 WP_079993350.1 competence protein ComX Regulator

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22297.08 Da        Isoelectric Point: 10.0375

>NTDB_id=1135488 DQM39_RS08555 WP_079993350.1 1628145..1628696(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC8225]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLRRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVSYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=1135488 DQM39_RS08555 WP_079993350.1 1628145..1628696(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain NCTC8225]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGTCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

45.455

84.153

0.383
  comX/sigX Streptococcus mutans UA159

44.444

83.607

0.372

Multiple sequence alignment