Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   H1W81_RS08725 Genome accession   NZ_LR824002
Coordinates   1680024..1680614 (-) Length   196 a.a.
NCBI ID   WP_002949732.1    Uniprot ID   Q5M5U4
Organism   Streptococcus thermophilus isolate STH_CIRM_67     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1675024..1685614
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W81_RS08695 (STHERMO_1948) - 1675233..1675997 (-) 765 WP_011225511.1 ABC transporter ATP-binding protein -
  H1W81_RS08700 (STHERMO_1949) - 1676000..1676950 (-) 951 WP_011225510.1 branched-chain amino acid ABC transporter permease -
  H1W81_RS08705 (STHERMO_1950) - 1676954..1677838 (-) 885 WP_011225509.1 branched-chain amino acid ABC transporter permease -
  H1W81_RS08710 (STHERMO_1951) - 1677882..1679057 (-) 1176 WP_011225508.1 ABC transporter substrate-binding protein -
  H1W81_RS08715 (STHERMO_1952) - 1679214..1679495 (-) 282 WP_002949736.1 YlbG family protein -
  H1W81_RS08720 (STHERMO_1953) - 1679488..1679937 (-) 450 WP_011225507.1 YlbF family regulator -
  H1W81_RS08725 (STHERMO_1954) clpP 1680024..1680614 (-) 591 WP_002949732.1 ATP-dependent Clp protease proteolytic subunit Regulator
  H1W81_RS08730 (STHERMO_1955) upp 1680752..1681381 (-) 630 WP_002946740.1 uracil phosphoribosyltransferase -
  H1W81_RS09815 (STHERMO_1956) - 1681651..1681785 (-) 135 WP_014607987.1 hypothetical protein -
  H1W81_RS08740 (STHERMO_1957) - 1681823..1681993 (-) 171 WP_041828136.1 hypothetical protein -
  H1W81_RS08745 (STHERMO_1958) - 1682069..1683232 (-) 1164 WP_011680761.1 MalY/PatB family protein -
  H1W81_RS08750 (STHERMO_1959) - 1683243..1684337 (-) 1095 WP_002946733.1 cystathionine gamma-synthase -
  H1W81_RS08755 (STHERMO_1960) - 1684641..1685234 (-) 594 Protein_1668 cation transporting ATPase C-terminal domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21577.62 Da        Isoelectric Point: 4.4829

>NTDB_id=1132357 H1W81_RS08725 WP_002949732.1 1680024..1680614(-) (clpP) [Streptococcus thermophilus isolate STH_CIRM_67]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPIEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNNLEQILADNSGQ
PIEKVHVDAERDNWMSAQETLEYGFIDEIMTNNQLK

Nucleotide


Download         Length: 591 bp        

>NTDB_id=1132357 H1W81_RS08725 WP_002949732.1 1680024..1680614(-) (clpP) [Streptococcus thermophilus isolate STH_CIRM_67]
ATGATTCCGGTAGTTATTGAACAAACATCACGTGGTGAACGTTCTTATGACATTTACTCACGTTTGCTCAAGGATCGTAT
TATCATGTTAACAGGTCCTATAGAAGATAATATGGCAAACTCAATTATCGCTCAACTCTTGTTCTTGGATGCTCAAGACA
ATACAAAAGATATCTATCTGTATGTTAATACACCTGGTGGGTCAGTTTCAGCAGGCCTTGCCATTGTTGATACAATGAAC
TTCATCAAGTCTGATGTTCAAACCATCGTTATGGGGATGGCAGCATCAATGGGTACAATTATCGCTTCAAGCGGTACCAA
AGGTAAACGTTTCATGTTGCCAAATGCAGAATACATGATTCACCAACCAATGGGTGGTACTGGTGGTGGTACTCAACAAA
CAGATATGGCTATCGCTGCTGAACACTTGCTCAAGACTCGTAATAACTTGGAGCAAATCTTGGCTGATAATTCTGGTCAG
CCAATTGAAAAGGTTCATGTCGATGCTGAACGTGATAATTGGATGAGTGCCCAAGAAACACTTGAATATGGCTTCATTGA
TGAAATCATGACCAACAACCAATTAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M5U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus thermophilus LMG 18311

100

100

1
  clpP Streptococcus thermophilus LMD-9

100

100

1
  clpP Streptococcus pneumoniae D39

92.821

99.49

0.923
  clpP Streptococcus pneumoniae R6

92.821

99.49

0.923
  clpP Streptococcus pneumoniae TIGR4

92.821

99.49

0.923
  clpP Streptococcus pneumoniae Rx1

92.821

99.49

0.923
  clpP Streptococcus pyogenes MGAS315

89.796

100

0.898
  clpP Streptococcus pyogenes JRS4

89.796

100

0.898
  clpP Streptococcus mutans UA159

87.755

100

0.878
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.245

100

0.872
  clpP Lactococcus lactis subsp. cremoris KW2

86.735

100

0.867
  clpP Bacillus subtilis subsp. subtilis str. 168

59.184

100

0.592
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.549

98.469

0.577

Multiple sequence alignment