Detailed information NTG1132342

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: H1W81_RS05290
• Genome accession: NZ_LR824002
• Coordinates: 1017242..1017949 (+)
• Length: 235 a.a.
• NCBI ID: WP_011227274.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_67
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1012242..1022949

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W81_RS05260 (STHERMO_1149)	-	1012518..1012706 (+)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H1W81_RS05265 (STHERMO_1150)	endA	1012768..1013649 (+)	882	WP_011226089.1	DNA/RNA non-specific endonuclease	Machinery gene
H1W81_RS05270 (STHERMO_1151)	-	1013720..1014370 (-)	651	WP_011226088.1	amino acid ABC transporter permease	-
H1W81_RS05275 (STHERMO_1152)	-	1014382..1015080 (-)	699	WP_011226087.1	amino acid ABC transporter permease	-
H1W81_RS05280 (STHERMO_1153)	-	1015098..1015931 (-)	834	WP_011227276.1	transporter substrate-binding domain-containing protein	-
H1W81_RS05285 (STHERMO_1154)	-	1015943..1016710 (-)	768	WP_011227275.1	amino acid ABC transporter ATP-binding protein	-
H1W81_RS05290 (STHERMO_1156)	vicR	1017242..1017949 (+)	708	WP_011227274.1	response regulator YycF	Regulator
H1W81_RS05295 (STHERMO_1157)	vicK	1017942..1019282 (+)	1341	WP_011226083.1	cell wall metabolism sensor histidine kinase VicK	Regulator
H1W81_RS05300 (STHERMO_1158)	vicX	1019288..1020100 (+)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
H1W81_RS05305	-	1020160..1020521 (+)	362	Protein_995	YbaN family protein	-
H1W81_RS05310 (STHERMO_1159)	-	1020573..1021787 (-)	1215	WP_179971674.1	aminoacyltransferase	-
H1W81_RS05315 (STHERMO_1160)	yidA	1021789..1022598 (-)	810	WP_011226081.1	sugar-phosphatase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27115.09 Da
• Isoelectric Point: 5.0130

>NTDB_id=1132342 H1W81_RS05290 WP_011227274.1 1017242..1017949(+) (vicR) [Streptococcus thermophilus isolate STH_CIRM_67]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEIVKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1132342 H1W81_RS05290 WP_011227274.1 1017242..1017949(+) (vicR) [Streptococcus thermophilus isolate STH_CIRM_67]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAATTGTCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACTGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	84.681	100	0.847
micA	Streptococcus pneumoniae Cp1015	79.399	99.149	0.787
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.136	100	0.383