Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   H1W81_RS05295 Genome accession   NZ_LR824002
Coordinates   1017942..1019282 (+) Length   446 a.a.
NCBI ID   WP_011226083.1    Uniprot ID   A0A060BIR3
Organism   Streptococcus thermophilus isolate STH_CIRM_67     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1012942..1024282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W81_RS05270 (STHERMO_1151) - 1013720..1014370 (-) 651 WP_011226088.1 amino acid ABC transporter permease -
  H1W81_RS05275 (STHERMO_1152) - 1014382..1015080 (-) 699 WP_011226087.1 amino acid ABC transporter permease -
  H1W81_RS05280 (STHERMO_1153) - 1015098..1015931 (-) 834 WP_011227276.1 transporter substrate-binding domain-containing protein -
  H1W81_RS05285 (STHERMO_1154) - 1015943..1016710 (-) 768 WP_011227275.1 amino acid ABC transporter ATP-binding protein -
  H1W81_RS05290 (STHERMO_1156) vicR 1017242..1017949 (+) 708 WP_011227274.1 response regulator YycF Regulator
  H1W81_RS05295 (STHERMO_1157) vicK 1017942..1019282 (+) 1341 WP_011226083.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H1W81_RS05300 (STHERMO_1158) vicX 1019288..1020100 (+) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  H1W81_RS05305 - 1020160..1020521 (+) 362 Protein_995 YbaN family protein -
  H1W81_RS05310 (STHERMO_1159) - 1020573..1021787 (-) 1215 WP_179971674.1 aminoacyltransferase -
  H1W81_RS05315 (STHERMO_1160) yidA 1021789..1022598 (-) 810 WP_011226081.1 sugar-phosphatase -
  H1W81_RS05320 - 1022806..1023686 (+) 881 Protein_998 GNAT family N-acetyltransferase -
  H1W81_RS05325 (STHERMO_1164) - 1023778..1024164 (+) 387 WP_002953113.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50782.15 Da        Isoelectric Point: 5.2464

>NTDB_id=1132343 H1W81_RS05295 WP_011226083.1 1017942..1019282(+) (vicK) [Streptococcus thermophilus isolate STH_CIRM_67]
MTSIGLNITSFELALLFMLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMITDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1132343 H1W81_RS05295 WP_011226083.1 1017942..1019282(+) (vicK) [Streptococcus thermophilus isolate STH_CIRM_67]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTTCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTACTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCTAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

HAMP domain (HAMP)

(37-79)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060BIR3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.638

92.825

0.693
  micB Streptococcus pneumoniae Cp1015

66.282

97.085

0.644

Multiple sequence alignment