Detailed information NTG1131580

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: H1W91_RS04310
• Genome accession: NZ_LR822032
• Coordinates: 818450..819289 (+)
• Length: 279 a.a.
• NCBI ID: WP_180476947.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1050
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 813450..824289

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W91_RS04280 (STHERMO_0923)	-	813866..814393 (+)	528	WP_011681081.1	ECF transporter S component	-
H1W91_RS04285 (STHERMO_0924)	-	814417..814932 (+)	516	WP_014608251.1	transcription repressor NadR	-
H1W91_RS04290 (STHERMO_0925)	-	815027..815716 (+)	690	WP_011225885.1	XRE family transcriptional regulator	-
H1W91_RS04295 (STHERMO_0926)	ylqF	815844..816698 (+)	855	WP_002950602.1	ribosome biogenesis GTPase YlqF	-
H1W91_RS04300 (STHERMO_0927)	-	816685..817452 (+)	768	WP_180476946.1	ribonuclease HII	-
H1W91_RS04305 (STHERMO_0928)	-	817463..818383 (+)	921	WP_002950604.1	ROK family protein	-
H1W91_RS04310 (STHERMO_0929)	dprA	818450..819289 (+)	840	WP_180476947.1	DNA-processing protein DprA	Machinery gene
H1W91_RS04315 (STHERMO_0931)	topA	819457..821601 (+)	2145	WP_180476948.1	type I DNA topoisomerase	-
H1W91_RS04320 (STHERMO_0932)	-	821718..822542 (+)	825	WP_180476949.1	TraX family protein	-
H1W91_RS04325 (STHERMO_0933)	-	822578..823237 (+)	660	WP_011227158.1	response regulator transcription factor	-

Sequence

Protein

• Length: 279 a.a.
• Molecular weight: 31261.21 Da
• Isoelectric Point: 8.6571

>NTDB_id=1131580 H1W91_RS04310 WP_180476947.1 818450..819289(+) (dprA) [Streptococcus thermophilus isolate STH_CIRM_1050]
MNNFELFKLKAAGLTNLNILNILDYQKNQDKKLSLRDMAVVSKSKNAILFMEKYKNLDVKQLKEDFQRFPTLSIFDKEYP
IELKHSYNPPVLLFYQGNIDLLSKPKLAVVGARKCSETGKQSVRKIVHELGNAFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHYPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDIISEFS

Nucleotide

• Length: 840 bp

>NTDB_id=1131580 H1W91_RS04310 WP_180476947.1 818450..819289(+) (dprA) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGAATAACTTTGAACTTTTTAAACTAAAAGCTGCTGGATTGACGAATTTAAACATCCTTAACATTTTAGACTATCAAAA
AAATCAAGATAAAAAATTGAGCTTACGTGATATGGCAGTGGTATCTAAGTCTAAAAATGCCATTCTCTTTATGGAAAAAT
ACAAGAATTTAGATGTTAAGCAGCTTAAGGAAGATTTTCAACGTTTTCCGACCTTATCAATTTTTGATAAGGAGTATCCC
ATTGAGCTGAAACATTCCTATAATCCTCCTGTCCTCCTCTTTTATCAAGGGAATATTGATTTGCTAAGTAAACCCAAGTT
AGCAGTAGTTGGTGCCAGAAAGTGTTCTGAAACAGGCAAACAGTCTGTTCGAAAAATTGTTCATGAACTTGGGAATGCCT
TTACTATTGTAAGTGGCTTGGCGCGTGGAATTGATACTTGTGCTCATATGGAGGCCTTAAAAAATAAAGGTAACACCATT
GCAGTTATCGGGACTGGGCTAGACGTATATTATCCTAAAGAAAACAAAGCTTTACAGGACTATATGGCTAAAAATCATTT
AGTTCTTACAGAATACGGACCGGGTGAACAGCCACTTAAATACCATTATCCTGAACGAAATCGGATAATTTCTGGATTGT
GTCAAGGGGTTATGGTGGTTGAAGCCAAGCTTCGCTCGGGAAGTCTTATTACTTGTGAGCGTGCAATGGAAGAAGGAAGA
GATGTTTTCGCCATACCAGGAAATATTTTAGATGGAAAATCGGATGGATGCCATCACCTCATTCAAGAGGGCGCAAAGTG
CATTACTACAGGATTTGACATCATTTCAGAATTTTCATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	72.043	100	0.72
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.309	99.642	0.631
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.95	99.642	0.627
dprA/cilB/dalA	Streptococcus mitis SK321	62.95	99.642	0.627
dprA	Lactococcus lactis subsp. cremoris KW2	60.432	99.642	0.602
dprA	Latilactobacillus sakei subsp. sakei 23K	39.768	92.832	0.369
dprA	Acinetobacter baumannii strain A118	44.889	80.645	0.362
dprA	Bacillus subtilis subsp. subtilis str. 168	48.095	75.269	0.362