Detailed information NTG1131406

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: H1W89_RS04300
• Genome accession: NZ_LR822029
• Coordinates: 817448..818155 (+)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1035
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 812448..823155

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W89_RS04270 (STHERMO_0914)	-	812729..812917 (+)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
H1W89_RS04275 (STHERMO_0915)	endA	812979..813860 (+)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
H1W89_RS04280 (STHERMO_0916)	-	813931..814581 (-)	651	WP_100273221.1	amino acid ABC transporter permease	-
H1W89_RS04285 (STHERMO_0917)	-	814593..815291 (-)	699	WP_014608374.1	amino acid ABC transporter permease	-
H1W89_RS04290 (STHERMO_0918)	-	815309..816142 (-)	834	WP_179970665.1	transporter substrate-binding domain-containing protein	-
H1W89_RS04295 (STHERMO_0919)	-	816154..816921 (-)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
H1W89_RS04300 (STHERMO_0920)	vicR	817448..818155 (+)	708	WP_011681206.1	response regulator YycF	Regulator
H1W89_RS04305 (STHERMO_0921)	vicK	818148..819488 (+)	1341	WP_082308980.1	cell wall metabolism sensor histidine kinase VicK	Regulator
H1W89_RS04310 (STHERMO_0922)	vicX	819494..820306 (+)	813	WP_011681204.1	MBL fold metallo-hydrolase	Regulator
H1W89_RS04315 (STHERMO_0923)	-	820366..820727 (+)	362	Protein_799	YbaN family protein	-
H1W89_RS04320 (STHERMO_0924)	-	820779..821993 (-)	1215	WP_002953123.1	aminoacyltransferase	-
H1W89_RS04325 (STHERMO_0925)	yidA	821995..822804 (-)	810	WP_011226081.1	sugar-phosphatase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=1131406 H1W89_RS04300 WP_011681206.1 817448..818155(+) (vicR) [Streptococcus thermophilus isolate STH_CIRM_1035]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1131406 H1W89_RS04300 WP_011681206.1 817448..818155(+) (vicR) [Streptococcus thermophilus isolate STH_CIRM_1035]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCACTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387