Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   H1W89_RS04305 Genome accession   NZ_LR822029
Coordinates   818148..819488 (+) Length   446 a.a.
NCBI ID   WP_082308980.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1035     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 813148..824488
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W89_RS04280 (STHERMO_0916) - 813931..814581 (-) 651 WP_100273221.1 amino acid ABC transporter permease -
  H1W89_RS04285 (STHERMO_0917) - 814593..815291 (-) 699 WP_014608374.1 amino acid ABC transporter permease -
  H1W89_RS04290 (STHERMO_0918) - 815309..816142 (-) 834 WP_179970665.1 transporter substrate-binding domain-containing protein -
  H1W89_RS04295 (STHERMO_0919) - 816154..816921 (-) 768 WP_011681207.1 amino acid ABC transporter ATP-binding protein -
  H1W89_RS04300 (STHERMO_0920) vicR 817448..818155 (+) 708 WP_011681206.1 response regulator YycF Regulator
  H1W89_RS04305 (STHERMO_0921) vicK 818148..819488 (+) 1341 WP_082308980.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H1W89_RS04310 (STHERMO_0922) vicX 819494..820306 (+) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  H1W89_RS04315 (STHERMO_0923) - 820366..820727 (+) 362 Protein_799 YbaN family protein -
  H1W89_RS04320 (STHERMO_0924) - 820779..821993 (-) 1215 WP_002953123.1 aminoacyltransferase -
  H1W89_RS04325 (STHERMO_0925) yidA 821995..822804 (-) 810 WP_011226081.1 sugar-phosphatase -
  H1W89_RS04330 - 823012..823890 (+) 879 Protein_802 GNAT family N-acetyltransferase -
  H1W89_RS04335 (STHERMO_0928) - 823982..824368 (+) 387 WP_002953113.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50764.06 Da        Isoelectric Point: 5.3933

>NTDB_id=1131407 H1W89_RS04305 WP_082308980.1 818148..819488(+) (vicK) [Streptococcus thermophilus isolate STH_CIRM_1035]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYSEKLRIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1131407 H1W89_RS04305 WP_082308980.1 818148..819488(+) (vicK) [Streptococcus thermophilus isolate STH_CIRM_1035]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAGTGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.396

92.825

0.691
  micB Streptococcus pneumoniae Cp1015

66.282

97.085

0.644

Multiple sequence alignment