Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   H0514_RS04530 Genome accession   NZ_LR822020
Coordinates   888830..889537 (+) Length   235 a.a.
NCBI ID   WP_179971935.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_956     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 883830..894537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0514_RS04505 (STHERMO_1013) - 883995..885252 (+) 1258 WP_179971940.1 ISL3 family transposase -
  H0514_RS04510 (STHERMO_1016) - 885316..885966 (-) 651 WP_179971939.1 amino acid ABC transporter permease -
  H0514_RS04515 (STHERMO_1017) - 885978..886676 (-) 699 WP_179971938.1 amino acid ABC transporter permease -
  H0514_RS04520 (STHERMO_1018) - 886694..887527 (-) 834 WP_179971937.1 transporter substrate-binding domain-containing protein -
  H0514_RS04525 (STHERMO_1019) - 887539..888306 (-) 768 WP_179973337.1 amino acid ABC transporter ATP-binding protein -
  H0514_RS04530 (STHERMO_1021) vicR 888830..889537 (+) 708 WP_179971935.1 response regulator YycF Regulator
  H0514_RS04535 (STHERMO_1022) vicK 889530..890870 (+) 1341 WP_179971934.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H0514_RS04540 (STHERMO_1023) vicX 890876..891688 (+) 813 WP_179971933.1 MBL fold metallo-hydrolase Regulator
  H0514_RS04545 (STHERMO_1024) - 891748..892109 (+) 362 Protein_850 YbaN family protein -
  H0514_RS04550 (STHERMO_1025) - 892162..893376 (-) 1215 WP_179971932.1 aminoacyltransferase -
  H0514_RS04555 (STHERMO_1026) yidA 893378..894187 (-) 810 WP_179971931.1 sugar-phosphatase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27205.13 Da        Isoelectric Point: 4.8347

>NTDB_id=1131089 H0514_RS04530 WP_179971935.1 888830..889537(+) (vicR) [Streptococcus thermophilus isolate STH_CIRM_956]
MKKILVVDDERPISDIIKFNLTKEGYEVVTTFDGREALEQFEAEKPDLVILDLMLPELDGLEVVKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEDNSNFGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide


Download         Length: 708 bp        

>NTDB_id=1131089 H0514_RS04530 WP_179971935.1 888830..889537(+) (vicR) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGACCTTTGATGGTCGTGAAGCTTTGGAACAATTTGAAGCTGAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGTCAAGGAAATCCGTAAAACGAGCCACACACCAATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTAACTAAGCCATTTTCTAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACAATTGAAACTGCAGTAGAAGATAACTCTAACTTTGGCA
AGCAAGAAATTTCAATTGGTGAGTTGATTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAGATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

84.255

100

0.843
  micA Streptococcus pneumoniae Cp1015

78.97

99.149

0.783
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.022

98.298

0.443
  covR Streptococcus salivarius strain HSISS4

44.444

99.574

0.443
  scnR Streptococcus mutans UA159

38.983

100

0.391

Multiple sequence alignment