Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   H0514_RS04535 Genome accession   NZ_LR822020
Coordinates   889530..890870 (+) Length   446 a.a.
NCBI ID   WP_179971934.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_956     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 884530..895870
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0514_RS04510 (STHERMO_1016) - 885316..885966 (-) 651 WP_179971939.1 amino acid ABC transporter permease -
  H0514_RS04515 (STHERMO_1017) - 885978..886676 (-) 699 WP_179971938.1 amino acid ABC transporter permease -
  H0514_RS04520 (STHERMO_1018) - 886694..887527 (-) 834 WP_179971937.1 transporter substrate-binding domain-containing protein -
  H0514_RS04525 (STHERMO_1019) - 887539..888306 (-) 768 WP_179973337.1 amino acid ABC transporter ATP-binding protein -
  H0514_RS04530 (STHERMO_1021) vicR 888830..889537 (+) 708 WP_179971935.1 response regulator YycF Regulator
  H0514_RS04535 (STHERMO_1022) vicK 889530..890870 (+) 1341 WP_179971934.1 cell wall metabolism sensor histidine kinase VicK Regulator
  H0514_RS04540 (STHERMO_1023) vicX 890876..891688 (+) 813 WP_179971933.1 MBL fold metallo-hydrolase Regulator
  H0514_RS04545 (STHERMO_1024) - 891748..892109 (+) 362 Protein_850 YbaN family protein -
  H0514_RS04550 (STHERMO_1025) - 892162..893376 (-) 1215 WP_179971932.1 aminoacyltransferase -
  H0514_RS04555 (STHERMO_1026) yidA 893378..894187 (-) 810 WP_179971931.1 sugar-phosphatase -
  H0514_RS04560 - 894395..895259 (+) 865 Protein_853 GNAT family N-acetyltransferase -
  H0514_RS04565 (STHERMO_1029) - 895351..895737 (+) 387 WP_002953113.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50749.99 Da        Isoelectric Point: 5.2550

>NTDB_id=1131090 H0514_RS04535 WP_179971934.1 889530..890870(+) (vicK) [Streptococcus thermophilus isolate STH_CIRM_956]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLRIKGDSELLELANSLNDLSEV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETDPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=1131090 H0514_RS04535 WP_179971934.1 889530..890870(+) (vicK) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAAGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTACGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGAAGTC
TTTCGTTTGACACATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACCATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTAACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCTGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTTTTCGTGTCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAGAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTGATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCCGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGATTCTCAGTTGATTGTTTCTATTTCCGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTGTCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGGTCAAC
TTTTACAATTGTCCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(37-79)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.638

92.825

0.693
  micB Streptococcus pneumoniae Cp1015

66.282

97.085

0.644

Multiple sequence alignment