Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   H0511_RS00400 Genome accession   NZ_LR822017
Coordinates   69377..69565 (+) Length   62 a.a.
NCBI ID   WP_111679075.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_336     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 52428..69565 69377..69565 within 0


Gene organization within MGE regions


Location: 52428..69565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0511_RS00305 (STHERMO_0051) - 52428..53594 (-) 1167 WP_179974128.1 tyrosine-type recombinase/integrase -
  H0511_RS00310 (STHERMO_0052) - 53900..54466 (-) 567 WP_179974129.1 helix-turn-helix domain-containing protein -
  H0511_RS00315 (STHERMO_0053) - 54640..54837 (+) 198 WP_179974130.1 helix-turn-helix transcriptional regulator -
  H0511_RS00320 (STHERMO_0054) - 55082..55375 (+) 294 WP_179974131.1 hypothetical protein -
  H0511_RS00325 (STHERMO_0055) - 55379..55573 (+) 195 WP_179974132.1 hypothetical protein -
  H0511_RS00330 (STHERMO_0056) - 55587..55823 (+) 237 WP_023909301.1 hypothetical protein -
  H0511_RS00335 (STHERMO_0057) - 55810..56151 (+) 342 WP_232087343.1 hypothetical protein -
  H0511_RS00340 (STHERMO_0058) - 56153..56425 (+) 273 WP_179974133.1 MerR family transcriptional regulator -
  H0511_RS00345 (STHERMO_0059) - 56441..57301 (+) 861 WP_179974134.1 primase alpha helix C-terminal domain-containing protein -
  H0511_RS00350 (STHERMO_0061) - 57291..58800 (+) 1510 Protein_48 phage/plasmid primase, P4 family -
  H0511_RS00355 (STHERMO_0062) - 59096..59281 (+) 186 WP_179974135.1 hypothetical protein -
  H0511_RS00360 (STHERMO_0063) - 59298..59573 (+) 276 WP_179974136.1 hypothetical protein -
  H0511_RS00370 (STHERMO_0067) - 61091..61558 (+) 468 WP_232087344.1 hypothetical protein -
  H0511_RS00375 (STHERMO_0068) - 61941..62528 (+) 588 WP_011681030.1 hypothetical protein -
  H0511_RS00380 (STHERMO_0069) - 62592..63122 (+) 531 WP_179974139.1 OB-fold protein -
  H0511_RS09640 (STHERMO_0070) - 63241..63447 (+) 207 WP_162484320.1 hypothetical protein -
  H0511_RS09645 (STHERMO_0071) - 63689..63898 (+) 210 Protein_56 transposase -
  H0511_RS00390 (STHERMO_0072) - 64187..66904 (-) 2718 WP_179974140.1 DEAD/DEAH box helicase family protein -
  H0511_RS00395 (STHERMO_0073) - 66906..68831 (-) 1926 WP_179974141.1 DNA methyltransferase -
  H0511_RS00400 (STHERMO_0074) prx 69377..69565 (+) 189 WP_111679075.1 hypothetical protein Regulator

Sequence

Protein


Download         Length: 62 a.a.        Molecular weight: 7133.08 Da        Isoelectric Point: 4.5837

>NTDB_id=1130941 H0511_RS00400 WP_111679075.1 69377..69565(+) (prx) [Streptococcus thermophilus isolate STH_CIRM_336]
MLTYDEFKEAMDNGFIKGDTVQIVRKNGKIHDYVLDGERVEPHEILRLEKVSDIIKELGGDN

Nucleotide


Download         Length: 189 bp        

>NTDB_id=1130941 H0511_RS00400 WP_111679075.1 69377..69565(+) (prx) [Streptococcus thermophilus isolate STH_CIRM_336]
ATGCTAACCTATGATGAATTTAAAGAGGCAATGGACAATGGTTTTATTAAAGGTGATACTGTCCAGATTGTCCGAAAGAA
TGGTAAGATCCATGACTACGTTTTAGACGGTGAACGAGTTGAGCCACACGAAATATTGAGATTAGAAAAAGTATCGGATA
TAATAAAAGAACTAGGCGGAGACAACTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

60.345

93.548

0.565
  prx Streptococcus pyogenes MGAS8232

59.322

95.161

0.565
  prx Streptococcus pyogenes MGAS315

57.627

95.161

0.548
  prx Streptococcus pyogenes MGAS315

56.897

93.548

0.532
  prx Streptococcus pyogenes MGAS315

74.419

69.355

0.516
  prx Streptococcus pyogenes MGAS315

65.957

75.806

0.5
  prx Streptococcus pyogenes MGAS315

65.957

75.806

0.5

Multiple sequence alignment