Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   H0502_RS09190 Genome accession   NZ_LR822013
Coordinates   1782274..1783374 (+) Length   366 a.a.
NCBI ID   WP_120764773.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_32     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1777274..1788374
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0502_RS09180 (STHERMO_2045) - 1781008..1781370 (+) 363 WP_014608746.1 DUF1033 family protein -
  H0502_RS09185 (STHERMO_2046) comGA/cglA/cilD 1781451..1782392 (+) 942 WP_014608745.1 competence type IV pilus ATPase ComGA Machinery gene
  H0502_RS09190 (STHERMO_2047) comYB 1782274..1783374 (+) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  H0502_RS09195 (STHERMO_2048) comYC 1783371..1783697 (+) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H0502_RS09200 (STHERMO_2049) comGD 1783657..1784085 (+) 429 WP_253269448.1 competence type IV pilus minor pilin ComGD -
  H0502_RS09205 (STHERMO_2050) comGE 1784057..1784350 (+) 294 WP_082309154.1 competence type IV pilus minor pilin ComGE -
  H0502_RS09210 (STHERMO_2051) comYF 1784334..1784771 (+) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  H0502_RS09215 (STHERMO_2052) comGG 1784749..1785066 (+) 318 WP_082309152.1 competence type IV pilus minor pilin ComGG -
  H0502_RS09220 (STHERMO_2053) comYH 1785111..1786067 (+) 957 WP_084831205.1 class I SAM-dependent methyltransferase Machinery gene
  H0502_RS09225 (STHERMO_2054) - 1786123..1787316 (+) 1194 WP_179970807.1 acetate kinase -
  H0502_RS09230 (STHERMO_2055) - 1787565..1787762 (+) 198 WP_014727723.1 helix-turn-helix transcriptional regulator -
  H0502_RS10225 (STHERMO_2056) - 1787774..1788049 (+) 276 WP_232086463.1 CAAX protease -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41876.03 Da        Isoelectric Point: 10.1377

>NTDB_id=1130814 H0502_RS09190 WP_120764773.1 1782274..1783374(+) (comYB) [Streptococcus thermophilus isolate STH_CIRM_32]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLYQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=1130814 H0502_RS09190 WP_120764773.1 1782274..1783374(+) (comYB) [Streptococcus thermophilus isolate STH_CIRM_32]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACATCCTTGTCCCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGTATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.678

93.443

0.511
  comYB Streptococcus mutans UA159

54.678

93.443

0.511
  comYB Streptococcus gordonii str. Challis substr. CH1

51.17

93.443

0.478
  comGB/cglB Streptococcus mitis NCTC 12261

50.453

90.437

0.456
  comGB/cglB Streptococcus mitis SK321

49.697

90.164

0.448
  comGB/cglB Streptococcus pneumoniae Rx1

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae D39

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae R6

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae TIGR4

49.695

89.617

0.445
  comGB Lactococcus lactis subsp. cremoris KW2

45.758

90.164

0.413

Multiple sequence alignment