Detailed information NTG1130816

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: H0502_RS09210
• Genome accession: NZ_LR822013
• Coordinates: 1784334..1784771 (+)
• Length: 145 a.a.
• NCBI ID: WP_082309153.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_32
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1779334..1789771

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0502_RS09180 (STHERMO_2045)	-	1781008..1781370 (+)	363	WP_014608746.1	DUF1033 family protein	-
H0502_RS09185 (STHERMO_2046)	comGA/cglA/cilD	1781451..1782392 (+)	942	WP_014608745.1	competence type IV pilus ATPase ComGA	Machinery gene
H0502_RS09190 (STHERMO_2047)	comYB	1782274..1783374 (+)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
H0502_RS09195 (STHERMO_2048)	comYC	1783371..1783697 (+)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
H0502_RS09200 (STHERMO_2049)	comGD	1783657..1784085 (+)	429	WP_253269448.1	competence type IV pilus minor pilin ComGD	-
H0502_RS09205 (STHERMO_2050)	comGE	1784057..1784350 (+)	294	WP_082309154.1	competence type IV pilus minor pilin ComGE	-
H0502_RS09210 (STHERMO_2051)	comYF	1784334..1784771 (+)	438	WP_082309153.1	competence type IV pilus minor pilin ComGF	Machinery gene
H0502_RS09215 (STHERMO_2052)	comGG	1784749..1785066 (+)	318	WP_082309152.1	competence type IV pilus minor pilin ComGG	-
H0502_RS09220 (STHERMO_2053)	comYH	1785111..1786067 (+)	957	WP_084831205.1	class I SAM-dependent methyltransferase	Machinery gene
H0502_RS09225 (STHERMO_2054)	-	1786123..1787316 (+)	1194	WP_179970807.1	acetate kinase	-
H0502_RS09230 (STHERMO_2055)	-	1787565..1787762 (+)	198	WP_014727723.1	helix-turn-helix transcriptional regulator	-
H0502_RS10225 (STHERMO_2056)	-	1787774..1788049 (+)	276	WP_232086463.1	CAAX protease	-
H0502_RS10230 (STHERMO_2057)	-	1788093..1788431 (+)	339	WP_232086462.1	CPBP family intramembrane glutamic endopeptidase	-
H0502_RS09240 (STHERMO_2058)	-	1788505..1788948 (+)	444	WP_084829882.1	CAAX protease	-
H0502_RS09245 (STHERMO_2059)	-	1789045..1789707 (+)	663	WP_011227583.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16423.93 Da
• Isoelectric Point: 8.9531

>NTDB_id=1130816 H0502_RS09210 WP_082309153.1 1784334..1784771(+) (comYF) [Streptococcus thermophilus isolate STH_CIRM_32]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKQD
NQYLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=1130816 H0502_RS09210 WP_082309153.1 1784334..1784771(+) (comYF) [Streptococcus thermophilus isolate STH_CIRM_32]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTTAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGCAGGAT
AATCAATACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.156	97.241	0.566
comYF	Streptococcus mutans UA159	57.447	97.241	0.559
comGF/cglF	Streptococcus pneumoniae D39	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae Rx1	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae R6	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae TIGR4	48.571	96.552	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	47.518	97.241	0.462
comGF/cglF	Streptococcus mitis SK321	46.099	97.241	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	45.324	95.862	0.434