Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   STHERMO_RS07280 Genome accession   NZ_LR822006
Coordinates   1394868..1395563 (-) Length   231 a.a.
NCBI ID   WP_179970517.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_16     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1389868..1400563
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STHERMO_RS07265 (STHERMO_1607) - 1390679..1391224 (-) 546 WP_022096992.1 GNAT family N-acetyltransferase -
  STHERMO_RS07270 (STHERMO_1608) - 1391290..1392552 (-) 1263 WP_022096991.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  STHERMO_RS07275 (STHERMO_1609) - 1392638..1394878 (-) 2241 WP_179970516.1 DNA internalization-related competence protein ComEC/Rec2 -
  STHERMO_RS07280 (STHERMO_1610) comEA 1394868..1395563 (-) 696 WP_179970517.1 helix-hairpin-helix domain-containing protein Machinery gene
  STHERMO_RS07285 (STHERMO_1611) - 1395672..1396427 (-) 756 WP_002948862.1 lysophospholipid acyltransferase family protein -
  STHERMO_RS10280 (STHERMO_1612) - 1396627..1397160 (+) 534 WP_011226401.1 polysaccharide deacetylase family protein -
  STHERMO_RS09860 (STHERMO_1613) - 1397094..1397492 (+) 399 WP_288576965.1 peptidoglycan GlcNAc deacetylase -
  STHERMO_RS07295 (STHERMO_1614) - 1397542..1398306 (+) 765 WP_011226403.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  STHERMO_RS07300 (STHERMO_1615) - 1398310..1398579 (+) 270 WP_011226404.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24486.41 Da        Isoelectric Point: 4.6300

>NTDB_id=1130452 STHERMO_RS07280 WP_179970517.1 1394868..1395563(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_16]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKAGARVTDAIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTGTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=1130452 STHERMO_RS07280 WP_179970517.1 1394868..1395563(-) (comEA) [Streptococcus thermophilus isolate STH_CIRM_16]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGCAGGCGCTAGGGTGACAGA
TGCCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAGGTACTGGTCAGGTCTCTGACAAAGGA
GGGCAGGCTGTATCTAAGGATGGCAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(85-138)

Helix-hairpin-helix motif (HHH_3)

(167-228)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

98.701

100

0.987
  comEA/celA/cilE Streptococcus mitis SK321

41.048

99.134

0.407
  comEA/celA/cilE Streptococcus pneumoniae D39

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus pneumoniae R6

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus pneumoniae Rx1

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

39.474

98.701

0.39
  comEA/celA/cilE Streptococcus mitis NCTC 12261

38.158

98.701

0.377

Multiple sequence alignment