Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   GPW69_RS07390 Genome accession   NZ_LR738724
Coordinates   1497620..1498324 (-) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis isolate 9401240     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1492620..1503324
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS07375 vga(F) 1493726..1495111 (-) 1386 WP_044681027.1 ABC-F type ribosomal protection protein Vga(F) -
  GPW69_RS07380 vicX 1495468..1496271 (-) 804 WP_044681030.1 MBL fold metallo-hydrolase Regulator
  GPW69_RS07385 micB 1496278..1497627 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GPW69_RS07390 micA 1497620..1498324 (-) 705 WP_004298854.1 response regulator YycF Regulator
  GPW69_RS07395 - 1498518..1499279 (+) 762 WP_074391798.1 amino acid ABC transporter ATP-binding protein -
  GPW69_RS07400 - 1499290..1500129 (+) 840 WP_074391797.1 transporter substrate-binding domain-containing protein -
  GPW69_RS07405 - 1500144..1500842 (+) 699 WP_074391796.1 amino acid ABC transporter permease -
  GPW69_RS07410 - 1500857..1501516 (+) 660 WP_024384909.1 amino acid ABC transporter permease -
  GPW69_RS07415 - 1501562..1502434 (-) 873 WP_074391795.1 hypothetical protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=1129606 GPW69_RS07390 WP_004298854.1 1497620..1498324(-) (micA) [Streptococcus suis isolate 9401240]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1129606 GPW69_RS07390 WP_004298854.1 1497620..1498324(-) (micA) [Streptococcus suis isolate 9401240]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGCGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTCTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAAGTCGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGTGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGGACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment