Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   GPW69_RS07385 Genome accession   NZ_LR738724
Coordinates   1496278..1497627 (-) Length   449 a.a.
NCBI ID   WP_002935841.1    Uniprot ID   G7SGQ2
Organism   Streptococcus suis isolate 9401240     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1491278..1502627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW69_RS07370 pbp2b 1491559..1493634 (-) 2076 WP_024413929.1 penicillin-binding protein PBP2B -
  GPW69_RS07375 vga(F) 1493726..1495111 (-) 1386 WP_044681027.1 ABC-F type ribosomal protection protein Vga(F) -
  GPW69_RS07380 vicX 1495468..1496271 (-) 804 WP_044681030.1 MBL fold metallo-hydrolase Regulator
  GPW69_RS07385 micB 1496278..1497627 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GPW69_RS07390 micA 1497620..1498324 (-) 705 WP_004298854.1 response regulator YycF Regulator
  GPW69_RS07395 - 1498518..1499279 (+) 762 WP_074391798.1 amino acid ABC transporter ATP-binding protein -
  GPW69_RS07400 - 1499290..1500129 (+) 840 WP_074391797.1 transporter substrate-binding domain-containing protein -
  GPW69_RS07405 - 1500144..1500842 (+) 699 WP_074391796.1 amino acid ABC transporter permease -
  GPW69_RS07410 - 1500857..1501516 (+) 660 WP_024384909.1 amino acid ABC transporter permease -
  GPW69_RS07415 - 1501562..1502434 (-) 873 WP_074391795.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51039.08 Da        Isoelectric Point: 4.5202

>NTDB_id=1129605 GPW69_RS07385 WP_002935841.1 1496278..1497627(-) (micB) [Streptococcus suis isolate 9401240]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1129605 GPW69_RS07385 WP_002935841.1 1496278..1497627(-) (micB) [Streptococcus suis isolate 9401240]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAACGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCTTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGATCGTTACACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTCTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTACATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTAACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
TTTATCGCGCATTGATAATCAGGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTGTCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTCTATCGCGTGGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SGQ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment