Detailed information NTG1129594

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: GPW69_RS04300
• Genome accession: NZ_LR738724
• Coordinates: 860467..861138 (+)
• Length: 223 a.a.
• NCBI ID: WP_074391083.1
• Uniprot ID: -
• Organism: Streptococcus suis isolate 9401240
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 855467..866138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPW69_RS04270	pstC	855493..856410 (+)	918	WP_002937619.1	phosphate ABC transporter permease subunit PstC	-
GPW69_RS04275	pstA	856400..857287 (+)	888	WP_074391085.1	phosphate ABC transporter permease PstA	-
GPW69_RS04280	pstB	857312..858115 (+)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-
GPW69_RS04285	pstB	858127..858885 (+)	759	WP_074391084.1	phosphate ABC transporter ATP-binding protein PstB	-
GPW69_RS04290	phoU	858912..859568 (+)	657	WP_024413748.1	phosphate signaling complex protein PhoU	-
GPW69_RS04295	-	859734..860273 (+)	540	WP_024413749.1	hypothetical protein	-
GPW69_RS04300	ciaR	860467..861138 (+)	672	WP_074391083.1	response regulator transcription factor	Regulator
GPW69_RS04305	ciaH	861131..862510 (+)	1380	WP_024413750.1	sensor histidine kinase	Regulator
GPW69_RS04310	-	862611..863840 (+)	1230	WP_074391082.1	transglutaminase domain-containing protein	-
GPW69_RS04315	rpsT	864104..864352 (-)	249	WP_012027069.1	30S ribosomal protein S20	-
GPW69_RS04320	coaA	864411..865331 (-)	921	WP_002935283.1	type I pantothenate kinase	-
GPW69_RS04325	-	865440..866030 (+)	591	WP_029188321.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25213.77 Da
• Isoelectric Point: 4.2183

>NTDB_id=1129594 GPW69_RS04300 WP_074391083.1 860467..861138(+) (ciaR) [Streptococcus suis isolate 9401240]
MIKILLVEDDLSLSNSVFDFLDDFADVIQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTYGDVTVDLSTNSTTVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

• Length: 672 bp

>NTDB_id=1129594 GPW69_RS04300 WP_074391083.1 860467..861138(+) (ciaR) [Streptococcus suis isolate 9401240]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGCCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATACAGGTTTTTGATGGCGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTTTTGAAAGAGTTACGTGAAAAAGGTGTTACGACCCCTGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGAGCTGATGACTACTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACTTATGGGGACGTGACCG
TTGACTTATCGACAAACTCTACAACTGTAAATGGCGAAGAAGTTGAATTGCTAGGAAAAGAATTCGATCTACTAGTCTAC
TTCTTGCAAAATCAAAATGTTATCTTGCCAAAAACTCAAATTTTTGACCGTATTTGGGGATTTGACAGTGACACTACTAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTCGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	89.686	100	0.897
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.053	100	0.386
vicR	Streptococcus mutans UA159	35.897	100	0.377
covR	Streptococcus salivarius strain HSISS4	36.283	100	0.368