Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   GPW48_RS07170 Genome accession   NZ_LR738720
Coordinates   1403244..1403948 (-) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis isolate GD-0001     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1398244..1408948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW48_RS07155 - 1400350..1400730 (-) 381 Protein_1353 ATP-binding cassette domain-containing protein -
  GPW48_RS07160 vicX 1401092..1401895 (-) 804 WP_023369694.1 MBL fold metallo-hydrolase Regulator
  GPW48_RS07165 micB 1401902..1403251 (-) 1350 WP_024405653.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GPW48_RS07170 micA 1403244..1403948 (-) 705 WP_002935840.1 response regulator YycF Regulator
  GPW48_RS07175 - 1404142..1404903 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  GPW48_RS07180 - 1404914..1405753 (+) 840 WP_023369690.1 transporter substrate-binding domain-containing protein -
  GPW48_RS07185 - 1405768..1406466 (+) 699 WP_015646621.1 amino acid ABC transporter permease -
  GPW48_RS07190 - 1406481..1407140 (+) 660 WP_002935828.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=1129403 GPW48_RS07170 WP_002935840.1 1403244..1403948(-) (micA) [Streptococcus suis isolate GD-0001]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=1129403 GPW48_RS07170 WP_002935840.1 1403244..1403948(-) (micA) [Streptococcus suis isolate GD-0001]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGCGA
ATTACAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTTGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment