Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   GPW48_RS07165 Genome accession   NZ_LR738720
Coordinates   1401902..1403251 (-) Length   449 a.a.
NCBI ID   WP_024405653.1    Uniprot ID   -
Organism   Streptococcus suis isolate GD-0001     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1396902..1408251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW48_RS07145 recR 1397578..1398174 (-) 597 WP_002935848.1 recombination mediator RecR -
  GPW48_RS07150 pbp2b 1398183..1400258 (-) 2076 WP_024405652.1 penicillin-binding protein PBP2B -
  GPW48_RS07155 - 1400350..1400730 (-) 381 Protein_1353 ATP-binding cassette domain-containing protein -
  GPW48_RS07160 vicX 1401092..1401895 (-) 804 WP_023369694.1 MBL fold metallo-hydrolase Regulator
  GPW48_RS07165 micB 1401902..1403251 (-) 1350 WP_024405653.1 cell wall metabolism sensor histidine kinase VicK Regulator
  GPW48_RS07170 micA 1403244..1403948 (-) 705 WP_002935840.1 response regulator YycF Regulator
  GPW48_RS07175 - 1404142..1404903 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  GPW48_RS07180 - 1404914..1405753 (+) 840 WP_023369690.1 transporter substrate-binding domain-containing protein -
  GPW48_RS07185 - 1405768..1406466 (+) 699 WP_015646621.1 amino acid ABC transporter permease -
  GPW48_RS07190 - 1406481..1407140 (+) 660 WP_002935828.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51077.16 Da        Isoelectric Point: 4.4860

>NTDB_id=1129402 GPW48_RS07165 WP_024405653.1 1401902..1403251(-) (micB) [Streptococcus suis isolate GD-0001]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHINENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGYGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1129402 GPW48_RS07165 WP_024405653.1 1401902..1403251(-) (micB) [Streptococcus suis isolate GD-0001]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAGCAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGATATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACGCGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGCTGGCTCAGACACCTGAG
ATTGTGATTGATCACATCAATGAAAATGAAGAATTTCTGACTTTACGTGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCCTGGTAGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTATTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTTAG
CTTATCGCGCATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTTATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment