Detailed information NTG1128491

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: FQT45_RS07590
• Genome accession: NZ_LR595858
• Coordinates: 1557190..1557780 (-)
• Length: 196 a.a.
• NCBI ID: WP_003083781.1
• Uniprot ID: A0A4V0H7V7
• Organism: Streptococcus pseudoporcinus strain NCTC10228
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1552190..1562780

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FQT45_RS07560 (NCTC10228_01554)	-	1552246..1553010 (-)	765	WP_077322382.1	ABC transporter ATP-binding protein	-
FQT45_RS07565 (NCTC10228_01555)	-	1553011..1553964 (-)	954	WP_077322384.1	branched-chain amino acid ABC transporter permease	-
FQT45_RS07570 (NCTC10228_01556)	-	1553967..1554836 (-)	870	WP_077322386.1	branched-chain amino acid ABC transporter permease	-
FQT45_RS07575 (NCTC10228_01557)	-	1554879..1556051 (-)	1173	WP_077322388.1	ABC transporter substrate-binding protein	-
FQT45_RS07580 (NCTC10228_01558)	-	1556206..1556454 (-)	249	WP_007895846.1	DUF2129 domain-containing protein	-
FQT45_RS07585 (NCTC10228_01559)	-	1556424..1556900 (-)	477	WP_077322390.1	YlbF family regulator	-
FQT45_RS07590 (NCTC10228_01560)	clpP	1557190..1557780 (-)	591	WP_003083781.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
FQT45_RS07595 (NCTC10228_01561)	upp	1557991..1558620 (-)	630	WP_007895697.1	uracil phosphoribosyltransferase	-
FQT45_RS07600 (NCTC10228_01562)	-	1558848..1560482 (-)	1635	WP_077322392.1	polysaccharide biosynthesis protein	-
FQT45_RS07605 (NCTC10228_01563)	-	1560569..1562026 (+)	1458	WP_077322394.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21743.01 Da
• Isoelectric Point: 4.8856

>NTDB_id=1128491 FQT45_RS07590 WP_003083781.1 1557190..1557780(-) (clpP) [Streptococcus pseudoporcinus strain NCTC10228]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGAGSGTQQTDMAIVAEQLLKTRKRLEKILADNSGK
TIKQIHKDAERDYWMDAKETLEYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=1128491 FQT45_RS07590 WP_003083781.1 1557190..1557780(-) (clpP) [Streptococcus pseudoporcinus strain NCTC10228]
ATGATTCCTGTAGTTATTGAACAAACAAGTCGTGGAGAACGTTCTTATGATATCTATTCACGTCTCCTAAAAGATCGTAT
TATTATGCTAACTGGACCAGTTGAAGATAATATGGCAAATTCTATTATTGCACAGTTACTATTTTTGGACGCGCAAGATA
ATACTAAGGATATTTACCTCTATGTAAATACACCTGGAGGATCAGTTTCAGCTGGGTTAGCAATTGTTGATACGATGAAC
TTTATTAAATCAGATGTTCAAACGATTGTTATGGGGATGGCTGCCTCAATGGGAACAATCATTGCATCATCAGGTGCCAA
AGGCAAACGATTCATGCTACCAAATGCTGAATACTTAATTCATCAACCGATGGGTGGCGCTGGTAGTGGTACGCAACAAA
CAGATATGGCAATTGTTGCTGAACAATTGTTAAAAACACGGAAACGCCTTGAAAAAATCCTTGCTGATAATTCTGGTAAG
ACTATTAAACAAATTCACAAAGATGCAGAACGTGACTACTGGATGGATGCTAAGGAAACATTGGAATATGGCTTCATTGA
TGAAATCATGGAAAATAATGAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A4V0H7V7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	94.898	100	0.949
clpP	Streptococcus pyogenes JRS4	92.347	100	0.923
clpP	Streptococcus pyogenes MGAS315	92.347	100	0.923
clpP	Lactococcus lactis subsp. cremoris KW2	91.837	100	0.918
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	91.327	100	0.913
clpP	Streptococcus thermophilus LMD-9	89.286	100	0.893
clpP	Streptococcus thermophilus LMG 18311	89.286	100	0.893
clpP	Streptococcus pneumoniae Rx1	87.692	99.49	0.872
clpP	Streptococcus pneumoniae D39	87.692	99.49	0.872
clpP	Streptococcus pneumoniae R6	87.692	99.49	0.872
clpP	Streptococcus pneumoniae TIGR4	87.692	99.49	0.872
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.513	98.469	0.566
clpP	Bacillus subtilis subsp. subtilis str. 168	56.122	100	0.561