Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   FGL23_RS10385 Genome accession   NZ_LR594049
Coordinates   2147855..2150008 (-) Length   717 a.a.
NCBI ID   WP_061603261.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC10231     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2142855..2155008
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL23_RS10370 (NCTC10231_02076) purD 2143215..2144474 (-) 1260 WP_061603258.1 phosphoribosylamine--glycine ligase -
  FGL23_RS10375 (NCTC10231_02077) lytF 2144719..2146368 (+) 1650 WP_061603259.1 GBS Bsp-like repeat-containing protein Regulator
  FGL23_RS10380 (NCTC10231_02078) comB 2146487..2147845 (-) 1359 WP_061603260.1 competence pheromone export protein ComB Regulator
  FGL23_RS10385 (NCTC10231_02079) comA 2147855..2150008 (-) 2154 WP_061603261.1 peptide cleavage/export ABC transporter ComA Regulator
  FGL23_RS10390 (NCTC10231_02080) rpsD 2150468..2151079 (-) 612 WP_008810013.1 30S ribosomal protein S4 -
  FGL23_RS10395 (NCTC10231_02081) - 2151346..2152068 (-) 723 WP_061603262.1 ABC transporter ATP-binding protein -
  FGL23_RS10400 (NCTC10231_02082) - 2152068..2153069 (-) 1002 WP_138115475.1 ABC transporter substrate-binding protein -
  FGL23_RS10405 (NCTC10231_02083) - 2153110..2153862 (-) 753 WP_060554273.1 ABC transporter permease -
  FGL23_RS10410 (NCTC10231_02084) - 2153825..2154115 (-) 291 WP_060554280.1 thiamine-binding protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80669.64 Da        Isoelectric Point: 6.9125

>NTDB_id=1128010 FGL23_RS10385 WP_061603261.1 2147855..2150008(-) (comA) [Streptococcus gordonii strain NCTC10231]
MKFRKRHYRAQVDTRDCGVAALAMVFGYYGSYFSLATLREKAKTTNDGTTALGLVKVAEGLNFETRAFKADMGIFDLEDV
SYPFIVHVLKEGKLLHYYVVTGQDKHTIHIADPDPQVKMTKISRERFEQEWTGITIFLAPSPAYKPSQEKKNGLLDFIPL
LIKQKGLITNIVLATLLVTVINIVGSYYLQSIIDTYVPDHMKTTLGMISIGLIIVYILQQFLSYAQEYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEIVSRFTDANRIIDALASTILSIFLDVSIVSIIAIVLFSQNSSLFFLTLLGIPVYAL
IIFLFMKPFEKMNHETMEANSLLSSSIIEDINGIETIKSLTSEKQRYQKIDKEFVTYLKKSFAYGRSESLQKVLKAAARL
ILNVLILWLGATLVMDQKISLGQLITYNTLLVYFTNPLENIINLQTKLQSARVANERLNEVYLVQSEFEEEKLIKDLSHF
QADIDFRGVSYKYGYGANVLSEIDLHIPAGSKTSFVGVSGSGKTTLAKMMVHFYAPNQGDICLGGVNLNQLDKQALRQYI
NYLPQQPYVFNGTILENLLLGAREGTTQEDILRAVELAEIRSDIERMPLNYQTELSADGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIIDNLMALDKTIIFIAHRLTIAERSEQVVVLDQGRIVESGSHKELIEKEGFYHHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=1128010 FGL23_RS10385 WP_061603261.1 2147855..2150008(-) (comA) [Streptococcus gordonii strain NCTC10231]
ATGAAATTTAGGAAACGGCATTACAGAGCGCAAGTTGATACTAGGGATTGCGGTGTGGCAGCTCTGGCTATGGTTTTTGG
TTATTATGGATCGTATTTTTCCTTGGCTACACTACGAGAAAAGGCAAAAACGACTAATGATGGCACAACTGCTTTGGGTT
TGGTGAAAGTTGCTGAGGGCTTAAATTTTGAGACAAGGGCTTTTAAAGCTGATATGGGAATCTTTGATCTGGAAGATGTA
TCTTATCCTTTCATCGTTCATGTACTTAAGGAAGGGAAGCTCCTGCATTATTATGTTGTGACGGGACAAGATAAACACAC
GATTCATATTGCAGACCCAGATCCTCAAGTTAAGATGACAAAGATTTCACGAGAGCGTTTTGAACAGGAGTGGACAGGAA
TCACCATTTTCCTGGCTCCTAGTCCGGCCTATAAGCCTAGTCAGGAAAAGAAGAATGGGCTTTTGGATTTTATTCCCTTA
TTGATTAAACAGAAGGGATTGATTACTAATATTGTGCTTGCAACTTTGCTGGTAACAGTGATTAATATTGTTGGATCTTA
CTACCTTCAGTCGATTATTGATACTTATGTGCCTGATCATATGAAAACGACGCTGGGTATGATTTCTATCGGCTTGATTA
TTGTCTATATTTTGCAGCAATTCTTGTCTTATGCCCAAGAATATTTGCTTTTGGTTTTAGGGCAACGCCTATCAATTGAT
GTGATCTTATCCTATATCAAGCATGTTTTTCAGCTACCTATGTCATTTTTTGCGACAAGGCGGACAGGAGAAATAGTCTC
CCGTTTTACAGACGCCAATCGGATTATTGATGCTTTGGCCAGTACAATTTTGTCTATTTTCTTGGATGTGTCAATTGTGT
CGATCATTGCGATTGTTCTTTTTTCACAAAATAGCAGTCTTTTCTTTTTGACCTTGCTAGGAATCCCAGTTTACGCTCTC
ATTATTTTTCTTTTTATGAAACCTTTTGAAAAGATGAATCATGAGACGATGGAAGCAAACAGTCTGTTGTCGTCTTCCAT
CATTGAAGATATCAATGGGATTGAAACGATCAAGTCTTTGACCAGCGAAAAACAACGTTATCAGAAGATTGACAAGGAAT
TTGTGACTTATCTGAAAAAGTCTTTTGCATATGGACGTTCTGAGAGTTTGCAAAAAGTCTTGAAAGCGGCTGCTCGTTTG
ATTTTAAACGTCTTGATTTTATGGCTAGGAGCTACACTTGTCATGGATCAAAAAATCAGCCTTGGTCAGCTCATTACTTA
TAACACACTTCTAGTCTACTTTACTAATCCTTTGGAAAATATTATCAATTTACAAACGAAGTTACAGTCTGCACGAGTGG
CCAATGAGCGTCTCAATGAGGTCTATTTAGTCCAGTCTGAATTTGAAGAAGAGAAGCTTATTAAAGACTTGAGCCACTTT
CAGGCTGACATCGATTTTCGTGGAGTCAGTTATAAGTATGGCTATGGGGCCAATGTATTGTCAGAAATTGACTTGCATAT
TCCTGCTGGAAGTAAGACCAGCTTTGTTGGTGTATCCGGTTCAGGAAAAACAACCTTAGCCAAGATGATGGTGCATTTCT
ACGCACCAAATCAAGGAGATATTTGTCTGGGAGGAGTCAATCTCAATCAGCTGGATAAACAGGCACTGCGCCAATATATC
AACTATCTTCCCCAGCAACCGTATGTTTTTAATGGAACTATTTTGGAAAATTTACTCTTAGGTGCGCGTGAAGGCACGAC
TCAAGAAGATATTCTGCGGGCGGTAGAATTGGCAGAAATTAGGTCGGATATTGAGCGGATGCCTCTCAATTATCAGACAG
AGCTATCAGCAGATGGAGCAGGGATTTCAGGTGGTCAACGTCAGCGTATTGCTCTAGCAAGGGCTCTCTTGACAGATGCG
CCAGTGCTTATCTTAGATGAAGCAACAAGTAGTCTGGATATTCTAACAGAGAAGCGGATCATTGATAATTTGATGGCGCT
TGATAAGACGATTATTTTTATTGCGCATCGTTTGACTATTGCGGAACGTTCGGAGCAGGTGGTCGTTTTGGATCAAGGTA
GGATTGTTGAGAGTGGAAGTCATAAGGAGCTGATCGAAAAAGAAGGCTTTTACCACCATTTGGTCAATAGTTAG

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(170-438)

Peptidase C39 family (Peptidase_C39)

(7-142)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

98.187

100

0.982
  comA Streptococcus pneumoniae Rx1

81.172

100

0.812
  comA Streptococcus pneumoniae D39

81.172

100

0.812
  comA Streptococcus pneumoniae R6

81.172

100

0.812
  comA Streptococcus mitis NCTC 12261

81.032

100

0.81
  comA Streptococcus mitis SK321

80.893

100

0.809
  comA Streptococcus pneumoniae TIGR4

80.753

100

0.808
  comA/nlmT Streptococcus mutans UA159

64.993

100

0.65

Multiple sequence alignment