Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   FGL23_RS10380 Genome accession   NZ_LR594049
Coordinates   2146487..2147845 (-) Length   452 a.a.
NCBI ID   WP_061603260.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC10231     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2141487..2152845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL23_RS10365 (NCTC10231_02075) - 2141962..2143155 (-) 1194 WP_061603257.1 ATP-grasp domain-containing protein -
  FGL23_RS10370 (NCTC10231_02076) purD 2143215..2144474 (-) 1260 WP_061603258.1 phosphoribosylamine--glycine ligase -
  FGL23_RS10375 (NCTC10231_02077) lytF 2144719..2146368 (+) 1650 WP_061603259.1 GBS Bsp-like repeat-containing protein Regulator
  FGL23_RS10380 (NCTC10231_02078) comB 2146487..2147845 (-) 1359 WP_061603260.1 competence pheromone export protein ComB Regulator
  FGL23_RS10385 (NCTC10231_02079) comA 2147855..2150008 (-) 2154 WP_061603261.1 peptide cleavage/export ABC transporter ComA Regulator
  FGL23_RS10390 (NCTC10231_02080) rpsD 2150468..2151079 (-) 612 WP_008810013.1 30S ribosomal protein S4 -
  FGL23_RS10395 (NCTC10231_02081) - 2151346..2152068 (-) 723 WP_061603262.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 49878.15 Da        Isoelectric Point: 6.0866

>NTDB_id=1128009 FGL23_RS10380 WP_061603260.1 2146487..2147845(-) (comB) [Streptococcus gordonii strain NCTC10231]
MNEQFLESAEFYQKRYHNFASCLIVPSLILLVFLVGFSMLAKKEITISSRASVEASRVLAQIQSTSNQAIIANHLAENKE
VKKGELLIQYAVEGEGAQEQKFSSQLDLLKDQKGKLETLRSSLESGRNQFTEPDSYGYEQSFKDYQNQVESMTSSVNQQN
ATIASQNAAASQSQAELGGVISDVDSKLNDHRNLKNAIQSGVGIDASHPLYSLYQSYRNQLSLAEDKATAQSQIVAQLDG
QISQLEATAATYRVQYAGAGAQQAYASNLSSQLASLKAQYLVKVGQELTTLTQQILEAESNLKLQETVSKRGQILAEMDG
LLHLNPEVQGSTLVAEGTALAQIYPKITNERKIKIVTYVSSKDVSTIKNGDKVRFITADDANKQMILTSQISSIDANATQ
TKQGNFFKVECEMAVSKDQAKKLRYGLEGKFVMVTGEKTYFSYYMEKFFNLG

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=1128009 FGL23_RS10380 WP_061603260.1 2146487..2147845(-) (comB) [Streptococcus gordonii strain NCTC10231]
ATGAATGAACAATTTTTAGAAAGTGCAGAGTTTTATCAGAAACGTTATCATAATTTTGCTAGTTGTCTAATTGTGCCAAG
TCTTATTTTACTAGTATTTCTAGTTGGTTTTTCTATGCTGGCTAAAAAGGAAATTACAATTTCTAGCCGCGCTTCTGTAG
AAGCTAGCCGAGTGCTAGCTCAGATTCAGTCGACTAGTAACCAAGCTATCATTGCGAATCATTTGGCAGAAAACAAGGAG
GTCAAAAAAGGGGAGTTGCTAATCCAGTATGCAGTAGAAGGAGAGGGAGCTCAGGAACAGAAGTTTTCCAGCCAGCTTGA
CTTACTCAAAGATCAAAAGGGCAAACTAGAAACTTTGCGTTCCAGTTTAGAAAGCGGGCGTAATCAATTTACTGAGCCAG
ATAGTTATGGCTACGAACAAAGCTTTAAAGACTACCAGAATCAAGTAGAGAGTATGACTAGTTCTGTGAATCAGCAAAAT
GCTACGATTGCTTCCCAAAATGCAGCGGCCAGTCAGTCTCAGGCGGAACTTGGTGGTGTTATCAGTGATGTAGATAGCAA
ACTAAATGACCATCGAAACTTGAAAAATGCCATTCAGAGCGGGGTGGGTATAGATGCATCGCATCCTCTTTACTCCTTGT
ATCAGTCCTATCGTAATCAGTTGAGCCTGGCGGAGGATAAGGCAACAGCTCAAAGTCAGATTGTAGCTCAATTAGATGGG
CAAATCTCTCAATTAGAAGCAACAGCTGCGACTTATCGTGTCCAATATGCTGGTGCAGGCGCTCAACAAGCCTATGCTAG
CAATTTATCCAGTCAGTTGGCTTCACTGAAAGCCCAGTATCTGGTCAAGGTAGGACAAGAATTGACCACTCTGACTCAGC
AAATCTTGGAAGCCGAGAGCAATCTTAAACTTCAAGAAACAGTCTCTAAGCGAGGTCAGATTTTGGCTGAAATGGATGGC
TTGCTTCACTTAAATCCAGAAGTACAAGGATCTACTCTGGTGGCAGAAGGAACTGCTTTGGCTCAGATTTACCCCAAAAT
CACTAATGAAAGAAAAATCAAAATTGTCACATATGTTTCTTCCAAGGATGTATCTACTATTAAAAATGGAGACAAGGTGC
GCTTTATCACTGCTGATGATGCTAACAAACAAATGATTTTGACATCCCAAATTTCCAGTATTGATGCTAATGCTACCCAA
ACCAAACAGGGAAATTTCTTTAAAGTAGAATGCGAAATGGCTGTTAGTAAAGATCAAGCTAAGAAGCTCCGCTATGGCTT
GGAAGGTAAATTTGTCATGGTAACTGGGGAAAAGACTTATTTCAGCTATTATATGGAGAAGTTTTTTAATCTTGGTTGA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(314-426)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

99.336

100

0.993
  comB Streptococcus mitis NCTC 12261

56

99.558

0.558
  comB Streptococcus pneumoniae D39

55.778

99.558

0.555
  comB Streptococcus pneumoniae R6

55.778

99.558

0.555
  comB Streptococcus pneumoniae Rx1

55.778

99.558

0.555
  comB Streptococcus mitis SK321

55.333

99.558

0.551
  comB Streptococcus pneumoniae TIGR4

55.333

99.558

0.551

Multiple sequence alignment