Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | FGL21_RS10300 | Genome accession | NZ_LR594047 |
| Coordinates | 2068314..2068496 (-) | Length | 60 a.a. |
| NCBI ID | WP_138128179.1 | Uniprot ID | - |
| Organism | Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 2059101..2111972 | 2068314..2068496 | within | 0 |
| IS/Tn | 2066717..2068081 | 2068314..2068496 | flank | 233 |
Gene organization within MGE regions
Location: 2059101..2111972
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FGL21_RS10260 (NCTC11554_02131) | - | 2059101..2059568 (+) | 468 | WP_003054740.1 | 8-oxo-dGTP diphosphatase | - |
| FGL21_RS10265 (NCTC11554_02132) | groL | 2059784..2061409 (-) | 1626 | WP_003054752.1 | chaperonin GroEL | - |
| FGL21_RS10270 (NCTC11554_02133) | groES | 2061445..2061735 (-) | 291 | WP_003054738.1 | co-chaperone GroES | - |
| FGL21_RS10275 (NCTC11554_02134) | clpC | 2061913..2064357 (-) | 2445 | WP_003054754.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| FGL21_RS10280 (NCTC11554_02135) | - | 2064357..2064818 (-) | 462 | WP_003054759.1 | CtsR family transcriptional regulator | - |
| FGL21_RS10285 | - | 2065014..2065217 (-) | 204 | WP_003053018.1 | cold-shock protein | - |
| FGL21_RS11460 (NCTC11554_02137) | - | 2065719..2066324 (+) | 606 | WP_223846053.1 | amidohydrolase family protein | - |
| FGL21_RS10295 (NCTC11554_02138) | - | 2066717..2068081 (-) | 1365 | WP_014612625.1 | IS1182 family transposase | - |
| FGL21_RS10300 (NCTC11554_02139) | prx | 2068314..2068496 (-) | 183 | WP_138128179.1 | Paratox | Regulator |
| FGL21_RS10305 (NCTC11554_02140) | - | 2068735..2069892 (+) | 1158 | WP_138128182.1 | DNA/RNA non-specific endonuclease | - |
| FGL21_RS10310 (NCTC11554_02141) | - | 2070059..2071039 (-) | 981 | WP_138128184.1 | Abi family protein | - |
| FGL21_RS10315 (NCTC11554_02142) | - | 2071333..2072547 (-) | 1215 | WP_138128186.1 | peptidoglycan amidohydrolase family protein | - |
| FGL21_RS10320 (NCTC11554_02144) | - | 2072658..2072843 (-) | 186 | WP_011184796.1 | holin | - |
| FGL21_RS10325 (NCTC11554_02145) | - | 2072840..2073139 (-) | 300 | WP_023077839.1 | hypothetical protein | - |
| FGL21_RS10330 (NCTC11554_02146) | - | 2073150..2073758 (-) | 609 | WP_138128188.1 | hypothetical protein | - |
| FGL21_RS10335 (NCTC11554_02147) | - | 2073761..2074192 (-) | 432 | WP_138128190.1 | DUF1617 family protein | - |
| FGL21_RS10340 (NCTC11554_02148) | - | 2074205..2076223 (-) | 2019 | WP_138128192.1 | gp58-like family protein | - |
| FGL21_RS10345 (NCTC11554_02149) | - | 2076234..2076869 (-) | 636 | WP_138128194.1 | hypothetical protein | - |
| FGL21_RS10350 (NCTC11554_02150) | - | 2076869..2077924 (-) | 1056 | WP_138128196.1 | hyaluronoglucosaminidase | - |
| FGL21_RS10355 (NCTC11554_02151) | - | 2077921..2080065 (-) | 2145 | WP_138128198.1 | phage tail spike protein | - |
| FGL21_RS10360 (NCTC11554_02152) | - | 2080062..2080778 (-) | 717 | WP_138128200.1 | distal tail protein Dit | - |
| FGL21_RS10365 (NCTC11554_02153) | - | 2080775..2084035 (-) | 3261 | WP_138128276.1 | tape measure protein | - |
| FGL21_RS10370 (NCTC11554_02154) | - | 2084025..2084606 (-) | 582 | WP_138128203.1 | bacteriophage Gp15 family protein | - |
| FGL21_RS10375 (NCTC11554_02155) | - | 2084610..2085044 (-) | 435 | WP_010922086.1 | hypothetical protein | - |
| FGL21_RS10380 (NCTC11554_02156) | - | 2085088..2085552 (-) | 465 | WP_138128205.1 | phage tail protein | - |
| FGL21_RS10385 (NCTC11554_02157) | - | 2085552..2085950 (-) | 399 | WP_138128207.1 | minor capsid protein | - |
| FGL21_RS10390 (NCTC11554_02158) | - | 2085947..2086303 (-) | 357 | WP_065361215.1 | minor capsid protein | - |
| FGL21_RS10395 (NCTC11554_02159) | - | 2086303..2086635 (-) | 333 | WP_111679814.1 | minor capsid protein | - |
| FGL21_RS10400 (NCTC11554_02160) | - | 2086625..2087041 (-) | 417 | WP_111679813.1 | hypothetical protein | - |
| FGL21_RS10405 (NCTC11554_02161) | - | 2087095..2087913 (-) | 819 | WP_111679812.1 | N4-gp56 family major capsid protein | - |
| FGL21_RS10410 (NCTC11554_02162) | - | 2087917..2088531 (-) | 615 | WP_111711580.1 | hypothetical protein | - |
| FGL21_RS10415 (NCTC11554_02163) | - | 2088669..2088935 (-) | 267 | WP_115283414.1 | hypothetical protein | - |
| FGL21_RS10420 (NCTC11554_02164) | - | 2089009..2089236 (-) | 228 | WP_111679809.1 | hypothetical protein | - |
| FGL21_RS10425 (NCTC11554_02165) | - | 2089233..2090729 (-) | 1497 | WP_111711579.1 | phage minor capsid protein | - |
| FGL21_RS10430 (NCTC11554_02166) | - | 2090734..2092236 (-) | 1503 | WP_111711578.1 | phage portal protein | - |
| FGL21_RS10435 (NCTC11554_02167) | - | 2092250..2093536 (-) | 1287 | WP_280641434.1 | PBSX family phage terminase large subunit | - |
| FGL21_RS10440 (NCTC11554_02168) | - | 2093539..2094015 (-) | 477 | WP_030127706.1 | terminase small subunit | - |
| FGL21_RS10450 (NCTC11554_02170) | - | 2094725..2095162 (-) | 438 | WP_003052405.1 | DUF1492 domain-containing protein | - |
| FGL21_RS11295 (NCTC11554_02171) | - | 2095524..2095694 (-) | 171 | WP_002987493.1 | hypothetical protein | - |
| FGL21_RS10455 (NCTC11554_02172) | - | 2095691..2096242 (-) | 552 | WP_138128209.1 | DUF1642 domain-containing protein | - |
| FGL21_RS10460 (NCTC11554_02173) | - | 2096344..2096583 (-) | 240 | WP_138083800.1 | hypothetical protein | - |
| FGL21_RS10465 (NCTC11554_02174) | - | 2096585..2096812 (-) | 228 | WP_138083799.1 | hypothetical protein | - |
| FGL21_RS10470 (NCTC11554_02175) | - | 2096809..2097729 (-) | 921 | WP_138128211.1 | N-6 DNA methylase | - |
| FGL21_RS10475 (NCTC11554_02176) | - | 2097732..2098001 (-) | 270 | WP_172601656.1 | hypothetical protein | - |
| FGL21_RS10480 (NCTC11554_02177) | - | 2098001..2098177 (-) | 177 | WP_032460883.1 | hypothetical protein | - |
| FGL21_RS10485 (NCTC11554_02178) | - | 2098174..2098563 (-) | 390 | WP_138128215.1 | YopX family protein | - |
| FGL21_RS10490 (NCTC11554_02179) | - | 2098560..2098754 (-) | 195 | WP_138128217.1 | hypothetical protein | - |
| FGL21_RS10495 (NCTC11554_02180) | - | 2098741..2099253 (-) | 513 | WP_138128219.1 | crossover junction endodeoxyribonuclease RuvC | - |
| FGL21_RS10500 (NCTC11554_02181) | - | 2099250..2099585 (-) | 336 | WP_138128221.1 | hypothetical protein | - |
| FGL21_RS11300 (NCTC11554_02182) | - | 2099762..2099929 (-) | 168 | WP_172601651.1 | hypothetical protein | - |
| FGL21_RS10505 (NCTC11554_02183) | - | 2099939..2100736 (-) | 798 | WP_138128223.1 | PD-(D/E)XK nuclease-like domain-containing protein | - |
| FGL21_RS10510 (NCTC11554_02184) | - | 2100733..2101707 (-) | 975 | WP_138128225.1 | RecT family recombinase | - |
| FGL21_RS11575 | - | 2101704..2101886 (-) | 183 | WP_138128227.1 | hypothetical protein | - |
| FGL21_RS10520 (NCTC11554_02185) | - | 2101889..2102143 (-) | 255 | WP_138128229.1 | hypothetical protein | - |
| FGL21_RS10525 (NCTC11554_02186) | - | 2102154..2102294 (-) | 141 | WP_011017992.1 | hypothetical protein | - |
| FGL21_RS10530 (NCTC11554_02187) | - | 2102306..2102524 (-) | 219 | WP_136112612.1 | hypothetical protein | - |
| FGL21_RS11465 (NCTC11554_02188) | - | 2102505..2103371 (-) | 867 | WP_138128231.1 | DnaD domain protein | - |
| FGL21_RS10540 (NCTC11554_02189) | - | 2103487..2103930 (-) | 444 | WP_046176840.1 | hypothetical protein | - |
| FGL21_RS10545 (NCTC11554_02190) | - | 2104102..2104281 (-) | 180 | WP_012560974.1 | hypothetical protein | - |
| FGL21_RS10550 (NCTC11554_02191) | - | 2104417..2104611 (-) | 195 | WP_138128233.1 | hypothetical protein | - |
| FGL21_RS10555 (NCTC11554_02192) | - | 2104608..2104883 (-) | 276 | WP_138128235.1 | DNA-binding protein | - |
| FGL21_RS10560 | - | 2104941..2105126 (-) | 186 | WP_021340658.1 | helix-turn-helix transcriptional regulator | - |
| FGL21_RS10565 (NCTC11554_02193) | - | 2105269..2105487 (+) | 219 | WP_032467270.1 | hypothetical protein | - |
| FGL21_RS11535 (NCTC11554_02194) | - | 2105473..2105604 (-) | 132 | WP_002984298.1 | hypothetical protein | - |
| FGL21_RS10570 (NCTC11554_02195) | - | 2105655..2106029 (+) | 375 | WP_023610946.1 | DUF2513 domain-containing protein | - |
| FGL21_RS11305 (NCTC11554_02196) | - | 2106009..2106149 (-) | 141 | WP_003051781.1 | hypothetical protein | - |
| FGL21_RS10575 (NCTC11554_02197) | - | 2106181..2106909 (-) | 729 | WP_138128237.1 | phage antirepressor KilAC domain-containing protein | - |
| FGL21_RS10580 (NCTC11554_02198) | - | 2106940..2107140 (-) | 201 | WP_038433319.1 | helix-turn-helix transcriptional regulator | - |
| FGL21_RS10585 (NCTC11554_02199) | - | 2107193..2107885 (+) | 693 | WP_138128239.1 | DUF4145 domain-containing protein | - |
| FGL21_RS10590 (NCTC11554_02200) | - | 2107861..2108070 (-) | 210 | WP_138128241.1 | hypothetical protein | - |
| FGL21_RS10595 (NCTC11554_02201) | - | 2108104..2108262 (-) | 159 | WP_138128244.1 | hypothetical protein | - |
| FGL21_RS10600 (NCTC11554_02202) | - | 2108320..2108520 (+) | 201 | WP_138128246.1 | KTSC domain-containing protein | - |
| FGL21_RS11310 (NCTC11554_02203) | - | 2108517..2108666 (-) | 150 | WP_172601652.1 | hypothetical protein | - |
| FGL21_RS10605 (NCTC11554_02204) | - | 2109020..2109853 (+) | 834 | WP_138128248.1 | helix-turn-helix transcriptional regulator | - |
| FGL21_RS10610 (NCTC11554_02205) | - | 2109889..2110782 (+) | 894 | WP_000426896.1 | P63C domain-containing protein | - |
| FGL21_RS10615 (NCTC11554_02206) | - | 2110899..2111972 (+) | 1074 | WP_138128250.1 | site-specific integrase | - |
Sequence
Protein
Download Length: 60 a.a. Molecular weight: 6788.68 Da Isoelectric Point: 3.9286
>NTDB_id=1127882 FGL21_RS10300 WP_138128179.1 2068314..2068496(-) (prx) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554]
MLTYDEFKQAIDDGYIVGDTVAIVRKDGQIFDYVLPGEPVRLWEVATEEKVEEVLGELGK
MLTYDEFKQAIDDGYIVGDTVAIVRKDGQIFDYVLPGEPVRLWEVATEEKVEEVLGELGK
Nucleotide
Download Length: 183 bp
>NTDB_id=1127882 FGL21_RS10300 WP_138128179.1 2068314..2068496(-) (prx) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11554]
ATGCTAACATACGATGAGTTTAAGCAAGCGATCGATGACGGCTATATCGTAGGCGATACAGTAGCGATCGTGCGTAAAGA
CGGACAGATCTTTGATTATGTGTTGCCTGGTGAGCCTGTAAGATTGTGGGAAGTTGCGACAGAGGAAAAAGTGGAAGAGG
TGTTGGGTGAATTAGGCAAATAA
ATGCTAACATACGATGAGTTTAAGCAAGCGATCGATGACGGCTATATCGTAGGCGATACAGTAGCGATCGTGCGTAAAGA
CGGACAGATCTTTGATTATGTGTTGCCTGGTGAGCCTGTAAGATTGTGGGAAGTTGCGACAGAGGAAAAAGTGGAAGAGG
TGTTGGGTGAATTAGGCAAATAA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS8232 |
80 |
100 |
0.8 |
| prx | Streptococcus pyogenes MGAS315 |
80 |
100 |
0.8 |
| prx | Streptococcus pyogenes MGAS315 |
71.667 |
100 |
0.717 |
| prx | Streptococcus pyogenes MGAS315 |
71.667 |
100 |
0.717 |
| prx | Streptococcus pyogenes MGAS315 |
92.683 |
68.333 |
0.633 |
| prx | Streptococcus pyogenes MGAS315 |
87.805 |
68.333 |
0.6 |
| prx | Streptococcus pyogenes MGAS315 |
78.049 |
68.333 |
0.533 |