Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   FGL18_RS03235 Genome accession   NZ_LR594046
Coordinates   614821..615531 (+) Length   236 a.a.
NCBI ID   WP_003049952.1    Uniprot ID   A0A9X9SIG1
Organism   Streptococcus dysgalactiae strain NCTC6403     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 609821..620531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL18_RS03210 (NCTC6403_00658) - 610499..611494 (+) 996 WP_138125095.1 DUF3114 domain-containing protein -
  FGL18_RS03215 (NCTC6403_00659) - 611591..612238 (-) 648 WP_138125097.1 amino acid ABC transporter permease -
  FGL18_RS03220 (NCTC6403_00660) - 612253..612954 (-) 702 WP_138125099.1 amino acid ABC transporter permease -
  FGL18_RS03225 (NCTC6403_00661) - 612968..613768 (-) 801 WP_138125101.1 transporter substrate-binding domain-containing protein -
  FGL18_RS03230 (NCTC6403_00662) - 613768..614562 (-) 795 WP_003057217.1 amino acid ABC transporter ATP-binding protein -
  FGL18_RS03235 (NCTC6403_00663) vicR 614821..615531 (+) 711 WP_003049952.1 response regulator YycF Regulator
  FGL18_RS03240 (NCTC6403_00664) vicK 615524..616876 (+) 1353 WP_003049953.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGL18_RS03245 (NCTC6403_00665) vicX 616880..617689 (+) 810 WP_138125103.1 MBL fold metallo-hydrolase Regulator
  FGL18_RS03250 (NCTC6403_00666) rnc 617962..618654 (+) 693 WP_003057240.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27029.90 Da        Isoelectric Point: 4.9981

>NTDB_id=1127794 FGL18_RS03235 WP_003049952.1 614821..615531(+) (vicR) [Streptococcus dysgalactiae strain NCTC6403]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTVFEDEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1127794 FGL18_RS03235 WP_003049952.1 614821..615531(+) (vicR) [Streptococcus dysgalactiae strain NCTC6403]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAACTTGACAAAAGAAGGTTATGA
CATTGTGACCGCTTTTGATGGCCGTGAAGCTGTGACCGTGTTTGAAGACGAAAAACCGGATTTAATTATTCTTGATTTGA
TGTTACCGGAATTGGACGGCCTTGAAGTGGCCAAAGAAATCCGTAAAACCAGTCATGTGCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGCCTTGAAATTGGGGCAGATGATTATGTTACCAAACCCTTTTCAAATCGTGA
ACTATTAGCGCGTGTTAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGCCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTATTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.487

99.153

0.788
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

37.712

100

0.377

Multiple sequence alignment