Detailed information NTG1127795

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: FGL18_RS03240
• Genome accession: NZ_LR594046
• Coordinates: 615524..616876 (+)
• Length: 450 a.a.
• NCBI ID: WP_003049953.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain NCTC6403
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 610524..621876

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL18_RS03215 (NCTC6403_00659)	-	611591..612238 (-)	648	WP_138125097.1	amino acid ABC transporter permease	-
FGL18_RS03220 (NCTC6403_00660)	-	612253..612954 (-)	702	WP_138125099.1	amino acid ABC transporter permease	-
FGL18_RS03225 (NCTC6403_00661)	-	612968..613768 (-)	801	WP_138125101.1	transporter substrate-binding domain-containing protein	-
FGL18_RS03230 (NCTC6403_00662)	-	613768..614562 (-)	795	WP_003057217.1	amino acid ABC transporter ATP-binding protein	-
FGL18_RS03235 (NCTC6403_00663)	vicR	614821..615531 (+)	711	WP_003049952.1	response regulator YycF	Regulator
FGL18_RS03240 (NCTC6403_00664)	vicK	615524..616876 (+)	1353	WP_003049953.1	cell wall metabolism sensor histidine kinase VicK	Regulator
FGL18_RS03245 (NCTC6403_00665)	vicX	616880..617689 (+)	810	WP_138125103.1	MBL fold metallo-hydrolase	Regulator
FGL18_RS03250 (NCTC6403_00666)	rnc	617962..618654 (+)	693	WP_003057240.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51476.02 Da
• Isoelectric Point: 5.5557

>NTDB_id=1127795 FGL18_RS03240 WP_003049953.1 615524..616876(+) (vicK) [Streptococcus dysgalactiae strain NCTC6403]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEQALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=1127795 FGL18_RS03240 WP_003049953.1 615524..616876(+) (vicK) [Streptococcus dysgalactiae strain NCTC6403]
ATGACTAGAGATATCATCGGGAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTCAATCTGACCAAGGAGCAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGCTTTGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAGTCCTACTTGGAGGCTCTTGACGAAGGTGCCCTCAAG
GAAGATATTGCCCCAAGTTTTATCAAGGTTTCTCTTGACGAAACCAATCGGATGATGCGAATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTTGAGATGACCAATTTTACAGCTTTTATGACGTCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACTTCT
GTTTGGCTGGAAATTGATAACGATAAGATGACGCAGGTTATTGAAAATATCTTAAACAATGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACAGACACGCAATTGATTATTTCCATCTCAGACCAAGGTTTAGGCATTC
CGAAGAAGGACCTGCCCCTTATTTTTGACCGTTTTTACCGAGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATCTGGGCGAAAAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-165)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.671	92	0.678
micB	Streptococcus pneumoniae Cp1015	66.824	94.444	0.631