Detailed information NTG1127792

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: FGL18_RS02785
• Genome accession: NZ_LR594046
• Coordinates: 526218..528371 (-)
• Length: 717 a.a.
• NCBI ID: WP_003062135.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain NCTC6403
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 521218..533371

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL18_RS02765 (NCTC6403_00564)	comE/blpR	522395..523144 (+)	750	WP_129556053.1	response regulator transcription factor	Regulator
FGL18_RS02770 (NCTC6403_00565)	-	523145..524479 (+)	1335	WP_138124984.1	GHKL domain-containing protein	-
FGL18_RS02775 (NCTC6403_00566)	-	524627..524752 (-)	126	WP_011017462.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
FGL18_RS02780	-	524843..526207 (-)	1365	Protein_484	bacteriocin secretion accessory protein	-
FGL18_RS02785 (NCTC6403_00569)	comA/nlmT	526218..528371 (-)	2154	WP_003062135.1	peptide cleavage/export ABC transporter	Regulator
FGL18_RS02790 (NCTC6403_00570)	-	528652..528876 (+)	225	WP_015057385.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
FGL18_RS02795 (NCTC6403_00571)	-	528899..529219 (+)	321	WP_030127173.1	hypothetical protein	-
FGL18_RS02800 (NCTC6403_00572)	-	529454..529855 (+)	402	WP_138124986.1	hypothetical protein	-
FGL18_RS10775	-	530111..530358 (+)	248	Protein_489	hypothetical protein	-
FGL18_RS02805	-	530380..530634 (+)	255	WP_197733578.1	CPBP family intramembrane glutamic endopeptidase	-
FGL18_RS02810 (NCTC6403_00573)	-	530863..531782 (+)	920	Protein_491	hypothetical protein	-
FGL18_RS02815 (NCTC6403_00574)	-	531858..532136 (-)	279	WP_138124988.1	StcA family protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80558.51 Da
• Isoelectric Point: 7.0109

>NTDB_id=1127792 FGL18_RS02785 WP_003062135.1 526218..528371(-) (comA/nlmT) [Streptococcus dysgalactiae strain NCTC6403]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVVYQNKKNYLIIGDPDPTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS

Nucleotide

• Length: 2154 bp

>NTDB_id=1127792 FGL18_RS02785 WP_003062135.1 526218..528371(-) (comA/nlmT) [Streptococcus dysgalactiae strain NCTC6403]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGATTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCGTCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACCCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTTTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTCTTTGCAACACGTCGGACAGGAGAAATCATTTC
ACGGTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCCACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTCCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGACTATCTGGATAAATCTTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACCAAACTTCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAATTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCGCTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGCA
AAATTATTGAAATAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTAGTTAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.867	99.721	0.727
comA	Streptococcus mitis NCTC 12261	67.647	99.582	0.674
comA	Streptococcus mitis SK321	67.227	99.582	0.669
comA	Streptococcus pneumoniae Rx1	67.227	99.582	0.669
comA	Streptococcus pneumoniae D39	67.227	99.582	0.669
comA	Streptococcus pneumoniae R6	67.227	99.582	0.669
comA	Streptococcus pneumoniae TIGR4	66.947	99.582	0.667
comA	Streptococcus gordonii str. Challis substr. CH1	66.017	100	0.661