Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | FGL16_RS04575 | Genome accession | NZ_LR594043 |
| Coordinates | 864699..864890 (+) | Length | 63 a.a. |
| NCBI ID | WP_024405272.1 | Uniprot ID | - |
| Organism | Streptococcus suis strain NCTC10237 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 815674..864890 | 864699..864890 | within | 0 |
Gene organization within MGE regions
Location: 815674..864890
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FGL16_RS04245 (NCTC10237_00818) | parE | 815674..817617 (+) | 1944 | WP_014735918.1 | DNA topoisomerase IV subunit B | - |
| FGL16_RS04250 (NCTC10237_00819) | - | 817665..818009 (+) | 345 | WP_014735917.1 | hypothetical protein | - |
| FGL16_RS04255 (NCTC10237_00820) | - | 818058..818660 (+) | 603 | WP_014735916.1 | Fic family protein | - |
| FGL16_RS04260 (NCTC10237_00821) | - | 818693..819196 (+) | 504 | WP_014735915.1 | YkvA family protein | - |
| FGL16_RS04265 (NCTC10237_00822) | - | 819225..819785 (+) | 561 | WP_014735914.1 | GTP pyrophosphokinase | - |
| FGL16_RS04270 (NCTC10237_00823) | - | 819809..821155 (+) | 1347 | WP_014735913.1 | hypothetical protein | - |
| FGL16_RS04275 (NCTC10237_00824) | parC | 821179..823632 (+) | 2454 | WP_014735912.1 | DNA topoisomerase IV subunit A | - |
| FGL16_RS04280 (NCTC10237_00825) | - | 823853..824470 (+) | 618 | WP_014735911.1 | DUF4230 domain-containing protein | - |
| FGL16_RS04285 (NCTC10237_00826) | - | 824581..825603 (+) | 1023 | WP_014735910.1 | branched-chain amino acid aminotransferase | - |
| FGL16_RS04290 (NCTC10237_00827) | - | 825670..825903 (+) | 234 | WP_012775068.1 | DUF2969 domain-containing protein | - |
| FGL16_RS04305 (NCTC10237_00830) | rpsA | 826506..827711 (+) | 1206 | WP_013730343.1 | 30S ribosomal protein S1 | - |
| FGL16_RS04315 (NCTC10237_00832) | - | 827892..828953 (-) | 1062 | WP_029694723.1 | tyrosine-type recombinase/integrase | - |
| FGL16_RS04320 (NCTC10237_00833) | - | 829092..830108 (-) | 1017 | WP_024405314.1 | Abi family protein | - |
| FGL16_RS04325 (NCTC10237_00834) | - | 830294..831052 (-) | 759 | WP_024405315.1 | ImmA/IrrE family metallo-endopeptidase | - |
| FGL16_RS04330 (NCTC10237_00835) | - | 831055..831438 (-) | 384 | WP_024405316.1 | helix-turn-helix transcriptional regulator | - |
| FGL16_RS10910 (NCTC10237_00836) | - | 831730..831870 (+) | 141 | WP_153308540.1 | hypothetical protein | - |
| FGL16_RS10915 (NCTC10237_00837) | - | 831859..832026 (-) | 168 | WP_153308541.1 | hypothetical protein | - |
| FGL16_RS04335 (NCTC10237_00838) | - | 832106..832471 (+) | 366 | WP_024405317.1 | hypothetical protein | - |
| FGL16_RS04340 (NCTC10237_00839) | - | 832422..832616 (-) | 195 | WP_024405318.1 | hypothetical protein | - |
| FGL16_RS04345 (NCTC10237_00840) | - | 832676..832888 (+) | 213 | WP_024381154.1 | hypothetical protein | - |
| FGL16_RS04350 (NCTC10237_00841) | - | 832892..833089 (+) | 198 | WP_024405319.1 | hypothetical protein | - |
| FGL16_RS04355 (NCTC10237_00843) | - | 833319..833573 (-) | 255 | WP_024405320.1 | hypothetical protein | - |
| FGL16_RS10920 (NCTC10237_00844) | - | 833654..833815 (+) | 162 | WP_171009920.1 | hypothetical protein | - |
| FGL16_RS04360 (NCTC10237_00846) | - | 833971..834660 (-) | 690 | WP_024405321.1 | DUF4145 domain-containing protein | - |
| FGL16_RS04365 (NCTC10237_00847) | - | 834724..835449 (+) | 726 | WP_024405322.1 | phage antirepressor KilAC domain-containing protein | - |
| FGL16_RS04370 (NCTC10237_00848) | - | 835497..835769 (+) | 273 | WP_024405323.1 | hypothetical protein | - |
| FGL16_RS04375 (NCTC10237_00849) | - | 835779..835967 (+) | 189 | WP_024376894.1 | hypothetical protein | - |
| FGL16_RS04380 (NCTC10237_00850) | - | 835969..836223 (+) | 255 | WP_024405324.1 | hypothetical protein | - |
| FGL16_RS10925 (NCTC10237_00851) | - | 836226..836381 (+) | 156 | WP_153308542.1 | hypothetical protein | - |
| FGL16_RS04385 (NCTC10237_00852) | - | 836374..837342 (+) | 969 | WP_024405325.1 | phage replisome organizer N-terminal domain-containing protein | - |
| FGL16_RS04390 (NCTC10237_00853) | - | 837329..837520 (+) | 192 | WP_024405326.1 | hypothetical protein | - |
| FGL16_RS10930 (NCTC10237_00854) | - | 837520..837690 (+) | 171 | WP_153308543.1 | hypothetical protein | - |
| FGL16_RS04395 (NCTC10237_00855) | - | 837721..837963 (+) | 243 | WP_024405327.1 | DUF3310 domain-containing protein | - |
| FGL16_RS04400 | - | 838084..839298 (+) | 1215 | Protein_774 | DNA cytosine methyltransferase | - |
| FGL16_RS04405 (NCTC10237_00859) | - | 839291..839647 (+) | 357 | WP_024405328.1 | hypothetical protein | - |
| FGL16_RS04410 (NCTC10237_00860) | - | 839640..840146 (+) | 507 | WP_024405329.1 | DUF1642 domain-containing protein | - |
| FGL16_RS10935 (NCTC10237_00861) | - | 840136..840297 (+) | 162 | WP_002936922.1 | hypothetical protein | - |
| FGL16_RS04415 (NCTC10237_00862) | - | 840686..841093 (+) | 408 | WP_024405330.1 | YopX family protein | - |
| FGL16_RS04420 (NCTC10237_00863) | - | 841086..841295 (+) | 210 | WP_024405331.1 | hypothetical protein | - |
| FGL16_RS04425 (NCTC10237_00864) | - | 841292..841495 (+) | 204 | WP_024405332.1 | hypothetical protein | - |
| FGL16_RS04430 (NCTC10237_00866) | ssbA | 841763..842179 (+) | 417 | WP_024405334.1 | single-stranded DNA-binding protein | Machinery gene |
| FGL16_RS04435 (NCTC10237_00867) | - | 842189..842452 (+) | 264 | WP_024405335.1 | hypothetical protein | - |
| FGL16_RS04440 (NCTC10237_00868) | - | 842445..842837 (+) | 393 | WP_024405336.1 | hypothetical protein | - |
| FGL16_RS10940 (NCTC10237_00869) | - | 842847..842987 (+) | 141 | WP_153308544.1 | hypothetical protein | - |
| FGL16_RS04445 (NCTC10237_00870) | - | 843161..843562 (+) | 402 | WP_024402323.1 | transcriptional regulator | - |
| FGL16_RS04450 (NCTC10237_00871) | tnpA | 843880..844344 (+) | 465 | WP_002939996.1 | IS200/IS605-like element ISSsu4 family transposase | - |
| FGL16_RS04460 (NCTC10237_00872) | - | 844509..845051 (+) | 543 | WP_024405254.1 | tyrosine-type recombinase/integrase | - |
| FGL16_RS04465 (NCTC10237_00874) | - | 845496..845795 (+) | 300 | Protein_788 | HNH endonuclease | - |
| FGL16_RS04470 (NCTC10237_00875) | - | 845940..846329 (+) | 390 | WP_024405256.1 | P27 family phage terminase small subunit | - |
| FGL16_RS04475 (NCTC10237_00876) | - | 846322..848118 (+) | 1797 | WP_024405257.1 | terminase large subunit | - |
| FGL16_RS04480 (NCTC10237_00877) | - | 848141..849343 (+) | 1203 | WP_024405258.1 | phage portal protein | - |
| FGL16_RS04485 (NCTC10237_00878) | - | 849330..849908 (+) | 579 | WP_024405259.1 | HK97 family phage prohead protease | - |
| FGL16_RS04490 (NCTC10237_00879) | - | 849905..851083 (+) | 1179 | WP_024405260.1 | phage major capsid protein | - |
| FGL16_RS04495 (NCTC10237_00880) | - | 851095..851439 (+) | 345 | WP_024405261.1 | hypothetical protein | - |
| FGL16_RS04500 (NCTC10237_00881) | - | 851442..851723 (+) | 282 | WP_024405262.1 | hypothetical protein | - |
| FGL16_RS04505 (NCTC10237_00882) | - | 851710..852009 (+) | 300 | WP_024405263.1 | phage head closure protein | - |
| FGL16_RS04510 (NCTC10237_00883) | - | 852006..852359 (+) | 354 | WP_024405264.1 | HK97 gp10 family phage protein | - |
| FGL16_RS04515 (NCTC10237_00884) | - | 852356..852586 (+) | 231 | WP_237658794.1 | hypothetical protein | - |
| FGL16_RS04520 (NCTC10237_00885) | - | 852692..853267 (+) | 576 | WP_024405265.1 | major tail protein | - |
| FGL16_RS04525 (NCTC10237_00886) | - | 853279..853698 (+) | 420 | WP_024390630.1 | hypothetical protein | - |
| FGL16_RS04530 (NCTC10237_00887) | - | 854006..857026 (+) | 3021 | WP_024405266.1 | phage tail tape measure protein | - |
| FGL16_RS04535 (NCTC10237_00888) | - | 857023..857745 (+) | 723 | WP_024405267.1 | hypothetical protein | - |
| FGL16_RS04540 (NCTC10237_00889) | - | 857746..860025 (+) | 2280 | WP_074404474.1 | phage tail spike protein | - |
| FGL16_RS11095 (NCTC10237_00890) | - | 860456..862282 (+) | 1827 | Protein_804 | gp58-like family protein | - |
| FGL16_RS04555 (NCTC10237_00891) | - | 862291..862500 (+) | 210 | WP_024405268.1 | hypothetical protein | - |
| FGL16_RS04560 (NCTC10237_00892) | - | 862503..862847 (+) | 345 | WP_024405269.1 | hypothetical protein | - |
| FGL16_RS04565 (NCTC10237_00893) | - | 862893..863273 (+) | 381 | Protein_807 | phage holin family protein | - |
| FGL16_RS10945 (NCTC10237_00895) | - | 863493..864332 (+) | 840 | WP_024405271.1 | N-acetylmuramoyl-L-alanine amidase | - |
| FGL16_RS04575 (NCTC10237_00896) | prx | 864699..864890 (+) | 192 | WP_024405272.1 | hypothetical protein | Regulator |
Sequence
Protein
Download Length: 63 a.a. Molecular weight: 7492.69 Da Isoelectric Point: 4.6412
>NTDB_id=1127631 FGL16_RS04575 WP_024405272.1 864699..864890(+) (prx) [Streptococcus suis strain NCTC10237]
MLEYEELKQAVDDGYIKGDTVMIVRRDGKIFDYVLPGEEVRPWEVVREEKVVDVMRELKKHVI
MLEYEELKQAVDDGYIKGDTVMIVRRDGKIFDYVLPGEEVRPWEVVREEKVVDVMRELKKHVI
Nucleotide
Download Length: 192 bp
>NTDB_id=1127631 FGL16_RS04575 WP_024405272.1 864699..864890(+) (prx) [Streptococcus suis strain NCTC10237]
ATGTTAGAATACGAAGAATTAAAACAAGCAGTAGATGACGGATATATCAAAGGCGACACGGTCATGATTGTTCGCAGGGA
CGGCAAGATATTTGATTATGTTTTGCCAGGCGAAGAGGTCAGACCATGGGAAGTGGTGAGAGAAGAGAAAGTAGTGGATG
TGATGAGGGAATTGAAAAAACATGTAATTTAG
ATGTTAGAATACGAAGAATTAAAACAAGCAGTAGATGACGGATATATCAAAGGCGACACGGTCATGATTGTTCGCAGGGA
CGGCAAGATATTTGATTATGTTTTGCCAGGCGAAGAGGTCAGACCATGGGAAGTGGTGAGAGAAGAGAAAGTAGTGGATG
TGATGAGGGAATTGAAAAAACATGTAATTTAG
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
66.667 |
95.238 |
0.635 |
| prx | Streptococcus pyogenes MGAS315 |
63.333 |
95.238 |
0.603 |
| prx | Streptococcus pyogenes MGAS8232 |
63.333 |
95.238 |
0.603 |
| prx | Streptococcus pyogenes MGAS315 |
58.333 |
95.238 |
0.556 |
| prx | Streptococcus pyogenes MGAS315 |
73.81 |
66.667 |
0.492 |
| prx | Streptococcus pyogenes MGAS315 |
75.61 |
65.079 |
0.492 |
| prx | Streptococcus pyogenes MGAS315 |
68.293 |
65.079 |
0.444 |