Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FGL16_RS00855 Genome accession   NZ_LR594043
Coordinates   131830..132867 (+) Length   345 a.a.
NCBI ID   WP_268739958.1    Uniprot ID   -
Organism   Streptococcus suis strain NCTC10237     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 126830..137867
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL16_RS00840 (NCTC10237_00163) - 129531..129896 (+) 366 WP_014735287.1 DUF1033 family protein -
  FGL16_RS00845 (NCTC10237_00164) - 129931..130881 (-) 951 WP_014735288.1 S66 peptidase family protein -
  FGL16_RS00850 comGA 130967..131918 (+) 952 Protein_123 competence type IV pilus ATPase ComGA -
  FGL16_RS00855 (NCTC10237_00167) comYB 131830..132867 (+) 1038 WP_268739958.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL16_RS00860 (NCTC10237_00168) comYC 132869..133150 (+) 282 WP_014735290.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL16_RS00865 (NCTC10237_00169) comGD 133131..133538 (+) 408 WP_014735291.1 competence type IV pilus minor pilin ComGD -
  FGL16_RS00870 (NCTC10237_00170) comYE 133510..133803 (+) 294 WP_024405248.1 competence type IV pilus minor pilin ComGE Machinery gene
  FGL16_RS00875 (NCTC10237_00171) comGF/cglF 133790..134224 (+) 435 WP_014735293.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGL16_RS00880 (NCTC10237_00172) comGG 134202..134723 (+) 522 WP_014735294.1 competence type IV pilus minor pilin ComGG -
  FGL16_RS00885 (NCTC10237_00173) comYH 134780..135733 (+) 954 WP_014735295.1 class I SAM-dependent methyltransferase Machinery gene
  FGL16_RS00890 (NCTC10237_00174) - 135783..136970 (+) 1188 WP_012775422.1 acetate kinase -
  FGL16_RS00895 (NCTC10237_00175) - 137285..137836 (+) 552 WP_012774908.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38785.65 Da        Isoelectric Point: 8.8871

>NTDB_id=1127611 FGL16_RS00855 WP_268739958.1 131830..132867(+) (comYB) [Streptococcus suis strain NCTC10237]
MRKLIGFLQQDISVFGKQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKCSQLLADSYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVSLAEVHGNTSLSLGHIQSYLENVSKVRKKLIEVATYPVILLGFLFLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLSGLSLVAVLAGMVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGGELTVYAAECWEDFFSRVNRAMQLIQPLA
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=1127611 FGL16_RS00855 WP_268739958.1 131830..132867(+) (comYB) [Streptococcus suis strain NCTC10237]
ATGCGCAAATTGATCGGCTTTTTGCAGCAGGACATATCAGTCTTCGGCAAGCAGAAACAGAAAAAATTGCCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCTAGCGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAT
GCAGTCAGCTTCTGGCAGATTCCTATACCCAGGTCTTGTCGGATGGCCTTCTTGCAGGAAAGCCGTTTTCAAGCCTATTA
GCGGATTTGCGTTTTTCAGATGCGGTGGTCACACAGGTGTCTCTGGCAGAAGTTCATGGCAATACCAGTCTGAGTTTGGG
GCATATTCAGTCCTATCTGGAAAATGTCAGCAAGGTGCGTAAAAAATTGATCGAAGTGGCAACTTATCCAGTTATCTTGC
TAGGTTTTCTGTTCTTGATTATGCTGGGTTTGAAAAACTATCTTTTACCTCAGTTGGAGGAAGGTAATGCAGCGACAGTG
CTGATTAATCATCTACCGACCATCTTTTTATCTCTAAGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACCAATAAAATTAAGGTCTTTTCCTGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTACCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCTTGATGCAAGAG
CAGCAGTCGCAGCTTTTTCGGGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGTTTTCACGAACACAT
CAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTATGGTCAGGTCAAGTCCAAGTTGGGTGGCGAGT
TGACGGTTTATGCAGCCGAGTGTTGGGAGGATTTCTTCTCTCGGGTCAATAGAGCCATGCAGCTGATTCAACCGCTGGCC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(35-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.45

99.13

0.629
  comGB/cglB Streptococcus mitis NCTC 12261

60

97.101

0.583
  comYB Streptococcus mutans UA140

58.944

98.841

0.583
  comYB Streptococcus mutans UA159

58.944

98.841

0.583
  comGB/cglB Streptococcus mitis SK321

59.701

97.101

0.58
  comGB/cglB Streptococcus pneumoniae R6

59.403

97.101

0.577
  comGB/cglB Streptococcus pneumoniae Rx1

59.403

97.101

0.577
  comGB/cglB Streptococcus pneumoniae D39

59.403

97.101

0.577
  comGB/cglB Streptococcus pneumoniae TIGR4

59.403

97.101

0.577
  comGB Lactococcus lactis subsp. cremoris KW2

50.148

97.681

0.49

Multiple sequence alignment