Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   FGL16_RS00870 Genome accession   NZ_LR594043
Coordinates   133510..133803 (+) Length   97 a.a.
NCBI ID   WP_024405248.1    Uniprot ID   A0A4V0DNI2
Organism   Streptococcus suis strain NCTC10237     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 128510..138803
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL16_RS00840 (NCTC10237_00163) - 129531..129896 (+) 366 WP_014735287.1 DUF1033 family protein -
  FGL16_RS00845 (NCTC10237_00164) - 129931..130881 (-) 951 WP_014735288.1 S66 peptidase family protein -
  FGL16_RS00850 comGA 130967..131918 (+) 952 Protein_123 competence type IV pilus ATPase ComGA -
  FGL16_RS00855 (NCTC10237_00167) comYB 131830..132867 (+) 1038 WP_268739958.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL16_RS00860 (NCTC10237_00168) comYC 132869..133150 (+) 282 WP_014735290.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL16_RS00865 (NCTC10237_00169) comGD 133131..133538 (+) 408 WP_014735291.1 competence type IV pilus minor pilin ComGD -
  FGL16_RS00870 (NCTC10237_00170) comYE 133510..133803 (+) 294 WP_024405248.1 competence type IV pilus minor pilin ComGE Machinery gene
  FGL16_RS00875 (NCTC10237_00171) comGF/cglF 133790..134224 (+) 435 WP_014735293.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGL16_RS00880 (NCTC10237_00172) comGG 134202..134723 (+) 522 WP_014735294.1 competence type IV pilus minor pilin ComGG -
  FGL16_RS00885 (NCTC10237_00173) comYH 134780..135733 (+) 954 WP_014735295.1 class I SAM-dependent methyltransferase Machinery gene
  FGL16_RS00890 (NCTC10237_00174) - 135783..136970 (+) 1188 WP_012775422.1 acetate kinase -
  FGL16_RS00895 (NCTC10237_00175) - 137285..137836 (+) 552 WP_012774908.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10771.63 Da        Isoelectric Point: 9.0978

>NTDB_id=1127613 FGL16_RS00870 WP_024405248.1 133510..133803(+) (comYE) [Streptococcus suis strain NCTC10237]
MVAIRKQKNKAYILLESLVALATLVTICSLILSAVDAGRRRQDWELEQQEVLNLAQMAVQTGQDNLALNGVTVQVQRTAD
KIIVFHEGKEVLSVVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1127613 FGL16_RS00870 WP_024405248.1 133510..133803(+) (comYE) [Streptococcus suis strain NCTC10237]
GTGGTCGCTATAAGAAAACAGAAGAATAAGGCTTATATTTTATTAGAAAGTTTGGTAGCCCTAGCTACCTTGGTGACCAT
TTGTAGCTTGATTTTGTCAGCGGTGGATGCTGGTCGTAGGCGACAGGATTGGGAATTGGAACAACAGGAGGTTCTCAATC
TAGCACAGATGGCTGTTCAGACCGGGCAAGATAACCTAGCCTTAAACGGTGTTACAGTTCAGGTTCAACGAACTGCGGAT
AAGATTATTGTTTTCCACGAGGGAAAGGAGGTTTTATCGGTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0DNI2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

53.608

100

0.536
  comYE Streptococcus mutans UA159

53.608

100

0.536
  comGE/cglE Streptococcus pneumoniae Rx1

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae D39

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae R6

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae TIGR4

40.217

94.845

0.381
  comGE/cglE Streptococcus mitis SK321

39.13

94.845

0.371
  comGE/cglE Streptococcus mitis NCTC 12261

39.13

94.845

0.371

Multiple sequence alignment