Detailed information NTG1127595

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: FGL06_RS08340
• Genome accession: NZ_LR594042
• Coordinates: 1675957..1676688 (-)
• Length: 243 a.a.
• NCBI ID: WP_074567288.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain NCTC8133
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1670957..1681688

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL06_RS08305 (NCTC8133_01681)	comD/comD3	1671567..1672958 (-)	1392	WP_231997657.1	GHKL domain-containing protein	Regulator
FGL06_RS08310 (NCTC8133_01682)	-	1672959..1673156 (-)	198	WP_126438119.1	hypothetical protein	-
FGL06_RS08315 (NCTC8133_01683)	-	1673318..1673611 (-)	294	WP_024344358.1	bacteriocin immunity protein	-
FGL06_RS08320 (NCTC8133_01684)	-	1673642..1673947 (-)	306	WP_033153382.1	bacteriocin immunity protein	-
FGL06_RS08325 (NCTC8133_01685)	-	1673967..1674254 (-)	288	WP_164554332.1	DUF3884 family protein	-
FGL06_RS08330 (NCTC8133_01686)	comC/comC1	1674451..1674606 (+)	156	WP_126438121.1	competence protein	Regulator
FGL06_RS08335 (NCTC8133_01687)	-	1674627..1675952 (-)	1326	WP_126438122.1	sensor histidine kinase	-
FGL06_RS08340 (NCTC8133_01688)	comE/comE1	1675957..1676688 (-)	732	WP_074567288.1	response regulator transcription factor	Regulator
FGL06_RS09360 (NCTC8133_01691)	-	1677551..1677655 (-)	105	WP_231997659.1	bacteriocin class II family protein	-
FGL06_RS08350 (NCTC8133_01693)	-	1678573..1679184 (-)	612	WP_231997660.1	thioredoxin family protein	-
FGL06_RS08360 (NCTC8133_01695)	-	1680020..1680139 (-)	120	WP_126438123.1	bacteriocin	-
FGL06_RS08365	-	1680508..1680834 (+)	327	Protein_1591	cysteine peptidase family C39 domain-containing protein	-

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 27968.81 Da
• Isoelectric Point: 5.9154

>NTDB_id=1127595 FGL06_RS08340 WP_074567288.1 1675957..1676688(-) (comE/comE1) [Streptococcus equinus strain NCTC8133]
MLDIFILEDNITQQFRIERQIEAIMEKNNWAYQHLEAFAASEDIIAKASEKKSHQIFFLDLEIKGDEKQGIDVARAIREK
DSTAIIAFVTTHSEFMLLTYQSLVGAIDFIDKNLNDAAFEQRLELCLKEALKHQKGNLGENSYLFETAKARIRVAYDDIL
YFETSPTVHRVILHTKTGQTEFYGTIAEVAKSDERLFKCHRSFVINVNNVAEFDKSTRTAYFANGSYCQVSRDKVKSLMA
EMR

Nucleotide

• Length: 732 bp

>NTDB_id=1127595 FGL06_RS08340 WP_074567288.1 1675957..1676688(-) (comE/comE1) [Streptococcus equinus strain NCTC8133]
ATGTTAGATATTTTTATCCTTGAGGATAATATCACACAACAATTTCGTATTGAGCGACAGATAGAGGCAATTATGGAAAA
GAATAATTGGGCTTATCAGCACTTGGAAGCTTTTGCGGCATCTGAGGATATTATTGCAAAAGCATCTGAAAAGAAGAGCC
ATCAGATTTTCTTTCTTGATTTAGAAATTAAAGGGGATGAAAAGCAAGGAATTGATGTGGCAAGAGCCATCCGTGAGAAG
GATTCGACAGCTATTATTGCTTTTGTAACGACTCATTCGGAGTTTATGCTTTTAACTTATCAGTCGTTGGTTGGTGCGAT
TGATTTCATTGATAAAAATTTAAATGATGCAGCTTTTGAACAACGTTTAGAGTTATGCTTGAAGGAAGCTCTTAAGCATC
AAAAAGGAAATTTAGGTGAGAATTCTTACCTTTTTGAAACTGCCAAAGCGAGAATTCGTGTAGCTTACGATGATATTTTA
TATTTTGAAACATCGCCAACCGTTCACCGAGTGATTTTACACACAAAAACAGGTCAAACTGAATTTTACGGAACGATTGC
GGAGGTTGCCAAATCAGATGAACGTCTGTTCAAATGTCACCGCTCTTTTGTGATTAATGTAAATAATGTTGCTGAATTTG
ATAAAAGTACCCGAACAGCTTATTTTGCAAATGGCTCTTACTGCCAAGTCTCACGAGACAAAGTCAAAAGCCTAATGGCA
GAAATGAGGTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-240)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	87.243	100	0.872
comE/comE2	Streptococcus equinus JB1	47.521	99.588	0.473
comE/blpR	Streptococcus mutans UA159	46.058	99.177	0.457
comE/comE2	Streptococcus gordonii strain NCTC7865	35.341	100	0.362
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	35.341	100	0.362