Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD3   Type   Regulator
Locus tag   FGL06_RS08305 Genome accession   NZ_LR594042
Coordinates   1671567..1672958 (-) Length   463 a.a.
NCBI ID   WP_231997657.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8133     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1666567..1677958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL06_RS08290 (NCTC8133_01678) comE/comE2 1667463..1668191 (-) 729 WP_033153377.1 LytR/AlgR family response regulator transcription factor Regulator
  FGL06_RS09355 comD/comD3 1668809..1669591 (-) 783 WP_231997655.1 sensor histidine kinase Regulator
  FGL06_RS08300 (NCTC8133_01680) comD/comD3 1670191..1671576 (-) 1386 WP_231997656.1 GHKL domain-containing protein Regulator
  FGL06_RS08305 (NCTC8133_01681) comD/comD3 1671567..1672958 (-) 1392 WP_231997657.1 GHKL domain-containing protein Regulator
  FGL06_RS08310 (NCTC8133_01682) - 1672959..1673156 (-) 198 WP_126438119.1 hypothetical protein -
  FGL06_RS08315 (NCTC8133_01683) - 1673318..1673611 (-) 294 WP_024344358.1 bacteriocin immunity protein -
  FGL06_RS08320 (NCTC8133_01684) - 1673642..1673947 (-) 306 WP_033153382.1 bacteriocin immunity protein -
  FGL06_RS08325 (NCTC8133_01685) - 1673967..1674254 (-) 288 WP_164554332.1 DUF3884 family protein -
  FGL06_RS08330 (NCTC8133_01686) comC/comC1 1674451..1674606 (+) 156 WP_126438121.1 competence protein Regulator
  FGL06_RS08335 (NCTC8133_01687) - 1674627..1675952 (-) 1326 WP_126438122.1 sensor histidine kinase -
  FGL06_RS08340 (NCTC8133_01688) comE/comE1 1675957..1676688 (-) 732 WP_074567288.1 response regulator transcription factor Regulator
  FGL06_RS09360 (NCTC8133_01691) - 1677551..1677655 (-) 105 WP_231997659.1 bacteriocin class II family protein -

Sequence

Protein


Download         Length: 463 a.a.        Molecular weight: 53303.27 Da        Isoelectric Point: 6.4031

>NTDB_id=1127593 FGL06_RS08305 WP_231997657.1 1671567..1672958(-) (comD/comD3) [Streptococcus equinus strain NCTC8133]
MRMIFMEVLGVLMNFSSFLILGVLFQQITKNKLTLGEWIFGILFIQIFSLGLAYSFVYRFNIAVLITKDVAPAACLMLIS
YHHNPRISFRYHLFYALYPINVHIILQRVYAYLLMMLFSIEITPRFDTAPIVTIIATIIAIFIPPVLYYLISKWLNIDIS
NVRKTLKNYLSSGVLTIVNILMVVYYFGNDYLALEVPSDSPILKIIVRTGAFIYLFLLFAFLFYLNFRHGQEQKNELLRN
QEMELKALENYSKHVESLYQEVRSFRHDYANVLMSLKVGIDQGDLDNIKKIYEEITADSAKLVKNNKFDLTRLANISDSA
VKSLMSAKFLEAENRSIEISLEVAEPMKNPKIPLISYIRILSILFDNAIEAALESENPKIAVANFYQDGDFVFIIENSTK
EKSVDLTKIFERGYSTKGENRGLGLATLVDFQDDYENLSVETSSFDYKFTQVVRVYEGEIKCS

Nucleotide


Download         Length: 1392 bp        

>NTDB_id=1127593 FGL06_RS08305 WP_231997657.1 1671567..1672958(-) (comD/comD3) [Streptococcus equinus strain NCTC8133]
ATGCGAATGATTTTTATGGAAGTATTAGGGGTTCTGATGAATTTTTCGTCTTTTTTAATACTAGGAGTTTTATTTCAGCA
GATAACTAAAAATAAACTCACTTTAGGAGAGTGGATTTTTGGAATATTATTTATTCAAATTTTTTCTCTTGGGCTTGCCT
ACAGTTTTGTCTATCGTTTTAATATTGCTGTTCTAATAACTAAGGATGTTGCGCCAGCAGCCTGTTTGATGTTAATTTCA
TATCATCATAATCCTAGAATTAGTTTTAGGTATCATCTTTTTTATGCTTTATATCCTATTAATGTTCACATAATTTTACA
AAGAGTATATGCCTATTTATTAATGATGCTCTTTTCAATTGAAATTACTCCTCGGTTTGACACTGCGCCGATAGTTACAA
TTATTGCTACAATTATCGCTATTTTTATACCGCCAGTTTTATATTATTTGATATCAAAGTGGCTTAATATTGATATTTCA
AATGTTCGAAAAACATTAAAAAATTATCTAAGTTCAGGAGTTTTGACGATTGTTAATATTTTAATGGTGGTTTATTATTT
CGGAAATGATTATCTTGCTTTAGAGGTACCATCAGATTCTCCAATTTTAAAAATAATTGTGAGAACTGGTGCTTTTATCT
ATTTATTCCTCCTTTTTGCATTCCTCTTCTATCTTAATTTCCGTCATGGGCAGGAGCAGAAAAATGAGCTGCTCCGCAAT
CAGGAAATGGAGCTTAAAGCTTTGGAAAATTATAGTAAACATGTGGAGAGTTTGTACCAAGAAGTACGCAGTTTTCGTCA
CGATTACGCTAATGTTTTGATGAGTTTGAAGGTTGGGATAGATCAAGGTGACCTTGATAATATCAAGAAAATTTACGAAG
AAATCACGGCTGACTCAGCGAAGTTGGTCAAAAACAATAAGTTTGACTTGACGCGACTAGCAAATATTTCAGACAGTGCC
GTCAAAAGCCTTATGTCGGCTAAATTTTTGGAGGCTGAAAATCGAAGTATTGAAATTAGTCTAGAAGTGGCAGAGCCGAT
GAAAAATCCCAAAATCCCACTGATTTCTTACATTCGAATTTTATCAATTCTGTTTGACAATGCCATCGAGGCTGCTTTAG
AGTCAGAAAATCCCAAAATCGCAGTAGCGAATTTTTACCAAGATGGAGATTTTGTGTTTATCATTGAAAATTCAACTAAG
GAAAAATCAGTGGATTTAACTAAGATTTTTGAGCGTGGGTACTCAACAAAAGGTGAGAATCGCGGTCTGGGTCTTGCGAC
ATTGGTTGATTTTCAGGATGATTATGAGAATTTGTCGGTTGAAACCAGCAGTTTTGATTACAAATTTACGCAAGTTGTGA
GAGTTTATGAGGGGGAAATTAAGTGCTCTTGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(358-453)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD3 Streptococcus equinus JB1

68.64

98.488

0.676
  comD/comD2 Streptococcus equinus JB1

76.101

68.683

0.523

Multiple sequence alignment