Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   FGL06_RS08290 Genome accession   NZ_LR594042
Coordinates   1667463..1668191 (-) Length   242 a.a.
NCBI ID   WP_033153377.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8133     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1662463..1673191
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL06_RS08260 (NCTC8133_01672) - 1662798..1663739 (-) 942 WP_024343528.1 3'-5' exoribonuclease YhaM family protein -
  FGL06_RS08265 (NCTC8133_01673) rmuC 1663729..1664943 (-) 1215 WP_371851905.1 DNA recombination protein RmuC -
  FGL06_RS08270 (NCTC8133_01674) - 1665006..1665638 (-) 633 WP_126438117.1 thiamine diphosphokinase -
  FGL06_RS08275 (NCTC8133_01675) rpe 1665631..1666293 (-) 663 WP_024343526.1 ribulose-phosphate 3-epimerase -
  FGL06_RS08280 (NCTC8133_01676) rsgA 1666300..1667172 (-) 873 WP_126438118.1 ribosome small subunit-dependent GTPase A -
  FGL06_RS08290 (NCTC8133_01678) comE/comE2 1667463..1668191 (-) 729 WP_033153377.1 LytR/AlgR family response regulator transcription factor Regulator
  FGL06_RS09355 comD/comD3 1668809..1669591 (-) 783 WP_231997655.1 sensor histidine kinase Regulator
  FGL06_RS08300 (NCTC8133_01680) comD/comD3 1670191..1671576 (-) 1386 WP_231997656.1 GHKL domain-containing protein Regulator
  FGL06_RS08305 (NCTC8133_01681) comD/comD3 1671567..1672958 (-) 1392 WP_231997657.1 GHKL domain-containing protein Regulator
  FGL06_RS08310 (NCTC8133_01682) - 1672959..1673156 (-) 198 WP_126438119.1 hypothetical protein -

Sequence

Protein


Download         Length: 242 a.a.        Molecular weight: 28297.51 Da        Isoelectric Point: 6.4962

>NTDB_id=1127591 FGL06_RS08290 WP_033153377.1 1667463..1668191(-) (comE/comE2) [Streptococcus equinus strain NCTC8133]
MIDIYVLEDNVNQQFRIERMIDELLDENQWDYRHFEIFSEPSHFPNFVEESCPQIFFLDIDINGDNKKGIEVAKKIREKS
RTATIVFVTTHSEFMLLTYRAQVSALDFIDKSDEDSSIKINLKNCLRKVIENQALTMPQEFFVFENNKATIRIPMDEILY
FETAESHRLKLVTKSGQRNFYGSIKEVMAANQTFFRSHKSYLINLDNVVCLDKKNSLVHFVGGQSCLVSKKYIKELKLKI
GV

Nucleotide


Download         Length: 729 bp        

>NTDB_id=1127591 FGL06_RS08290 WP_033153377.1 1667463..1668191(-) (comE/comE2) [Streptococcus equinus strain NCTC8133]
ATGATTGACATCTATGTATTGGAGGACAATGTAAATCAGCAATTTCGGATTGAAAGGATGATTGATGAACTACTTGATGA
AAATCAGTGGGACTATCGTCATTTTGAAATATTTAGTGAGCCGTCTCATTTTCCAAATTTTGTTGAGGAATCTTGCCCAC
AAATTTTTTTCTTAGATATTGATATCAATGGTGATAATAAAAAGGGAATTGAAGTCGCTAAGAAAATTAGGGAGAAATCT
AGAACAGCTACGATTGTTTTTGTTACGACGCATTCTGAGTTTATGTTGTTGACTTACCGAGCACAGGTTAGTGCACTTGA
TTTTATTGATAAGTCAGATGAAGACAGTTCGATAAAAATTAATTTAAAAAATTGTTTGCGAAAGGTCATCGAAAATCAGG
CTCTTACGATGCCACAGGAATTTTTTGTATTTGAAAATAATAAAGCTACTATTCGTATTCCGATGGATGAAATTCTTTAT
TTTGAAACAGCTGAAAGTCATCGACTGAAGTTGGTTACAAAGTCGGGACAACGTAATTTTTATGGTTCAATCAAAGAAGT
AATGGCTGCTAATCAGACCTTTTTTAGAAGCCACAAATCGTATCTGATTAATCTTGATAATGTTGTGTGCTTAGATAAAA
AGAATAGTTTGGTGCATTTTGTCGGTGGTCAATCTTGCCTTGTTTCAAAGAAATACATTAAAGAATTAAAGTTGAAAATA
GGTGTTTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

LytTr DNA-binding domain (LytTR)

(149-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus equinus JB1

74.167

99.174

0.736
  comE/comE1 Streptococcus equinus JB1

44.118

98.347

0.434
  comE/blpR Streptococcus mutans UA159

40.164

100

0.405
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.367

100

0.388
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.367

100

0.388

Multiple sequence alignment