Detailed information NTG1127567

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: FGL06_RS02995
• Genome accession: NZ_LR594042
• Coordinates: 561840..562520 (+)
• Length: 226 a.a.
• NCBI ID: WP_126437689.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain NCTC8133
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 556840..567520

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL06_RS02965 (NCTC8133_00594)	-	556858..558057 (+)	1200	WP_126437687.1	MFS transporter	-
FGL06_RS02970 (NCTC8133_00595)	-	558088..558750 (+)	663	WP_231997673.1	AraC family ligand binding domain-containing protein	-
FGL06_RS09305	-	558763..558954 (+)	192	Protein_521	helix-turn-helix domain-containing protein	-
FGL06_RS02975 (NCTC8133_00596)	-	558964..559854 (+)	891	WP_126437688.1	ROK family protein	-
FGL06_RS02980 (NCTC8133_00597)	-	559869..560144 (-)	276	WP_024344272.1	GIY-YIG nuclease family protein	-
FGL06_RS02985 (NCTC8133_00598)	-	560119..560880 (-)	762	WP_074450932.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
FGL06_RS02990 (NCTC8133_00599)	-	560999..561745 (+)	747	WP_024344274.1	lysophospholipid acyltransferase family protein	-
FGL06_RS02995 (NCTC8133_00600)	comEA	561840..562520 (+)	681	WP_126437689.1	helix-hairpin-helix domain-containing protein	Machinery gene
FGL06_RS03000 (NCTC8133_00601)	comEC/celB	562513..564744 (+)	2232	WP_126437690.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FGL06_RS03005 (NCTC8133_00602)	-	564850..565428 (+)	579	WP_126437691.1	HD domain-containing protein	-
FGL06_RS03010 (NCTC8133_00603)	-	565440..566162 (+)	723	WP_231997674.1	CYTH domain-containing protein	-
FGL06_RS03015 (NCTC8133_00604)	holA	566214..567251 (+)	1038	WP_164554306.1	DNA polymerase III subunit delta	-

Sequence

Protein

• Length: 226 a.a.
• Molecular weight: 24019.88 Da
• Isoelectric Point: 4.4812

>NTDB_id=1127567 FGL06_RS02995 WP_126437689.1 561840..562520(+) (comEA) [Streptococcus equinus strain NCTC8133]
MIEEMKEKILEHKTVASVLGTVLVMLVMFFAWSSMESHKAEVQNDLPALSTSFSASSGETSQPKTVASASKSESDKIFVD
IKGAVRKEGVYELTSGSRVTDVVKLAGGFTDDADKKSVNLAEKVADEAVIYVARVGEEVTPASTPSQAKNTAPSGAQQDA
DSAQINLNTATLEELQTISGIGAKRAQDIIDYRDNNGGFSSVDDLKNVSGIGEKTLEKLKAEVTVD

Nucleotide

• Length: 681 bp

>NTDB_id=1127567 FGL06_RS02995 WP_126437689.1 561840..562520(+) (comEA) [Streptococcus equinus strain NCTC8133]
ATGATTGAAGAGATGAAAGAAAAAATTTTAGAGCATAAAACTGTGGCATCAGTTTTGGGGACAGTTCTTGTTATGCTAGT
GATGTTTTTTGCTTGGTCTAGTATGGAAAGCCACAAAGCTGAAGTGCAAAATGATTTACCAGCATTGAGCACTAGCTTTT
CAGCAAGTAGTGGAGAAACATCTCAGCCAAAAACAGTAGCATCTGCTTCAAAGTCGGAATCAGATAAGATTTTCGTTGAT
ATTAAAGGTGCCGTCAGAAAAGAAGGTGTTTATGAATTAACATCAGGTAGTCGTGTGACAGATGTGGTCAAATTAGCTGG
CGGTTTTACAGATGATGCGGATAAGAAATCTGTTAATTTAGCTGAAAAAGTAGCGGACGAAGCAGTGATTTACGTGGCAA
GAGTTGGTGAAGAGGTCACACCAGCAAGTACCCCGTCTCAAGCTAAAAATACAGCACCAAGTGGAGCGCAGCAAGATGCG
GACTCAGCACAAATCAATCTTAATACTGCGACTTTAGAAGAACTTCAGACGATTTCTGGCATCGGCGCCAAACGTGCTCA
AGACATCATCGATTATCGTGATAACAACGGTGGATTTTCGTCAGTTGATGATTTGAAAAATGTGTCAGGTATTGGTGAGA
AGACCTTAGAAAAACTAAAAGCTGAGGTGACAGTTGATTAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (79-132)

• Helix-hairpin-helix motif (HHH_3) (163-224)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Streptococcus thermophilus LMD-9	47.436	100	0.491
comEA/celA/cilE	Streptococcus mitis SK321	47.111	99.558	0.469
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	45.778	99.558	0.456
comEA/celA/cilE	Streptococcus mitis NCTC 12261	44.444	99.558	0.442
comEA/celA/cilE	Streptococcus pneumoniae Rx1	43.556	99.558	0.434
comEA/celA/cilE	Streptococcus pneumoniae D39	43.556	99.558	0.434
comEA/celA/cilE	Streptococcus pneumoniae R6	43.556	99.558	0.434
comEA	Latilactobacillus sakei subsp. sakei 23K	39.462	98.673	0.389