Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   FGL12_RS10625 Genome accession   NZ_LR594041
Coordinates   2186220..2188373 (-) Length   717 a.a.
NCBI ID   WP_138101400.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC9124     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2181220..2193373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS10610 (NCTC9124_02141) purD 2181580..2182839 (-) 1260 WP_012131055.1 phosphoribosylamine--glycine ligase -
  FGL12_RS10615 (NCTC9124_02142) lytF 2183084..2184733 (+) 1650 WP_138101396.1 GBS Bsp-like repeat-containing protein Regulator
  FGL12_RS10620 (NCTC9124_02143) comB 2184852..2186210 (-) 1359 WP_138101398.1 competence pheromone export protein ComB Regulator
  FGL12_RS10625 (NCTC9124_02144) comA 2186220..2188373 (-) 2154 WP_138101400.1 peptide cleavage/export ABC transporter ComA Regulator
  FGL12_RS10630 (NCTC9124_02145) rpsD 2188827..2189438 (-) 612 WP_008810013.1 30S ribosomal protein S4 -
  FGL12_RS10635 (NCTC9124_02146) - 2189704..2190426 (-) 723 WP_008810014.1 ABC transporter ATP-binding protein -
  FGL12_RS10640 (NCTC9124_02147) - 2190426..2191424 (-) 999 WP_012131061.1 ABC transporter substrate-binding protein -
  FGL12_RS10645 (NCTC9124_02148) - 2191468..2192220 (-) 753 WP_041789832.1 ABC transporter permease -
  FGL12_RS10650 (NCTC9124_02149) - 2192183..2192473 (-) 291 WP_012131063.1 thiamine-binding protein -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80581.58 Da        Isoelectric Point: 6.9123

>NTDB_id=1127536 FGL12_RS10625 WP_138101400.1 2186220..2188373(-) (comA) [Streptococcus gordonii strain NCTC9124]
MKFRKQHYRAQVDTRDCGVAALAMIFGYYGSYFSLATLREKAKTTNDGTTALGLVKVAEGLNFETRAFKADMGIFDLEDV
SYPFIVHVLKEGKLLHYYVVTGQDKHTIHIADPDPQVKMTKISRERFEQEWTGITIFLAPSPAYKPSQEKKNGLLDFIPL
LIKQKGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDHMKTTLGMISIGLIIVYILQQFLSYAQEYLLLVLGQRLSID
VILSYIKHVFQLPMSFFATRRTGEIVSRFTDANRIIDALASTILSIFLDVSIVSIIAIVLFSQNSSLFFLTLLGIPVYAL
IIFLFMKPFEKMNHETMEANSLLSSSIIEDINGIETIKSLTSEKQRYQKIDKEFVTYLKKSFAYGRSESLQKVLKAAARL
ILNVLILWLGATLVMDQKISLGQLITYNTLLVYFTNPLENIINLQTKLQSARVANERLNEVYLVQSEFEEEKLIKDLSHF
QADIDFRGVSYKYGYGANVLSEIDLHIPAGSKTSFVGVSGSGKTTLAKMMVHFYAPNQGDICLGGVNLNQLDKQALRQYI
NYLPQQPYVFNGTILENLLLGAREGTTQEDILRAVELAEIRSDIERMPLNYQTELSADGAGISGGQRQRIALARALLTDA
PVLILDGATSSLDILTEKRIIDNLMALDKTIIFIVHRLTIAERSEQVVVLDQGRIVESGSHKELIEKEGFYHHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=1127536 FGL12_RS10625 WP_138101400.1 2186220..2188373(-) (comA) [Streptococcus gordonii strain NCTC9124]
ATGAAATTTAGGAAACAGCATTACAGAGCACAAGTTGACACTAGGGATTGCGGTGTTGCAGCTCTGGCTATGATTTTTGG
TTATTATGGATCGTATTTTTCCTTGGCTACACTACGAGAAAAGGCAAAAACTACCAATGATGGCACAACAGCTTTGGGTT
TGGTAAAAGTTGCTGAGGGCTTAAATTTTGAGACAAGGGCTTTTAAAGCTGATATGGGAATCTTTGATCTGGAAGATGTA
TCTTATCCCTTCATCGTTCATGTACTTAAGGAAGGGAAACTCCTGCATTATTATGTTGTAACGGGACAAGATAAACACAC
GATTCATATTGCAGACCCAGATCCTCAAGTTAAGATGACAAAGATTTCGCGAGAGCGTTTCGAACAGGAGTGGACAGGAA
TTACCATTTTCCTGGCTCCTAGTCCGGCCTATAAGCCTAGTCAGGAAAAGAAAAATGGGCTTTTAGATTTTATTCCCTTA
TTGATCAAGCAGAAGGGGTTGATTGCTAATATTGTACTTGCAACTTTGCTGGTAACGGTGATCAATATTGTTGGATCCTA
CTACCTTCAGTCGATTATTGATACTTATGTGCCTGATCATATGAAAACGACACTAGGTATGATTTCTATCGGCTTGATTA
TTGTCTACATTTTGCAGCAATTCTTGTCTTATGCCCAAGAATATTTACTCTTGGTTTTAGGGCAACGTCTATCAATTGAT
GTGATCTTATCCTATATCAAGCATGTTTTTCAGCTACCTATGTCATTTTTCGCGACAAGGCGGACAGGGGAAATTGTCTC
TCGTTTTACGGATGCCAATCGGATTATTGATGCCTTAGCCAGTACAATCTTGTCTATTTTCTTGGATGTGTCAATTGTGT
CGATCATTGCGATTGTTCTTTTTTCACAAAATAGCAGTCTTTTCTTTTTGACCTTGCTAGGAATCCCAGTTTACGCTCTC
ATTATTTTTCTTTTTATGAAACCTTTTGAAAAGATGAATCATGAGACGATGGAAGCAAACAGTCTGTTGTCGTCTTCCAT
CATTGAAGATATCAATGGGATTGAAACGATCAAGTCTTTGACCAGCGAAAAACAACGTTATCAGAAGATTGACAAGGAAT
TTGTGACTTATCTGAAAAAGTCTTTTGCATATGGACGTTCTGAGAGTTTGCAAAAAGTCTTGAAAGCGGCTGCTCGTTTG
ATTTTAAACGTCTTGATTTTATGGCTAGGAGCTACACTTGTCATGGATCAAAAAATCAGCCTTGGTCAGCTCATTACTTA
TAACACACTTCTAGTCTACTTTACTAATCCTTTGGAAAATATTATCAATTTACAAACGAAGTTACAGTCTGCACGAGTGG
CCAATGAGCGTCTCAATGAGGTCTATTTAGTCCAGTCTGAATTTGAAGAAGAGAAGCTTATTAAAGACTTGAGCCACTTT
CAGGCTGACATCGATTTTCGTGGAGTCAGTTATAAGTATGGCTATGGGGCCAATGTATTGTCAGAAATTGACTTGCATAT
TCCTGCTGGAAGTAAGACCAGCTTTGTTGGTGTATCCGGTTCAGGAAAAACAACCTTAGCCAAGATGATGGTGCATTTCT
ACGCACCAAATCAAGGAGATATTTGTCTGGGAGGAGTCAATCTCAATCAGCTGGATAAACAGGCACTGCGCCAATATATC
AACTATCTTCCCCAGCAACCGTATGTTTTTAATGGAACTATTTTGGAAAATTTACTCTTAGGTGCGCGTGAAGGCACGAC
TCAAGAAGATATTCTGCGGGCGGTAGAATTGGCAGAAATTAGGTCGGATATTGAGCGGATGCCTCTCAATTATCAGACAG
AGCTATCAGCAGATGGAGCAGGGATTTCAGGTGGTCAACGTCAGCGTATTGCTCTAGCAAGGGCTCTCTTGACAGATGCG
CCAGTGCTTATCTTAGATGGAGCAACAAGCAGTCTGGATATTCTAACGGAGAAGCGGATCATTGATAATTTGATGGCGCT
TGATAAGACGATTATTTTTATCGTGCATCGTTTGACTATTGCGGAACGTTCGGAGCAGGTGGTCGTTTTGGATCAAGGTA
GGATTGTTGAGAGTGGAAGTCATAAGGAGCTGATCGAAAAAGAAGGTTTTTACCACCATTTGGTCAATAGTTAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(170-438)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus gordonii str. Challis substr. CH1

98.047

100

0.98
  comA Streptococcus pneumoniae Rx1

80.753

100

0.808
  comA Streptococcus pneumoniae D39

80.753

100

0.808
  comA Streptococcus pneumoniae R6

80.753

100

0.808
  comA Streptococcus mitis NCTC 12261

80.614

100

0.806
  comA Streptococcus mitis SK321

80.474

100

0.805
  comA Streptococcus pneumoniae TIGR4

80.335

100

0.803
  comA/nlmT Streptococcus mutans UA159

64.296

100

0.643

Multiple sequence alignment