Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   FGL12_RS10620 Genome accession   NZ_LR594041
Coordinates   2184852..2186210 (-) Length   452 a.a.
NCBI ID   WP_138101398.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC9124     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2179852..2191210
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS10605 (NCTC9124_02140) - 2180327..2181520 (-) 1194 WP_138101395.1 ATP-grasp domain-containing protein -
  FGL12_RS10610 (NCTC9124_02141) purD 2181580..2182839 (-) 1260 WP_012131055.1 phosphoribosylamine--glycine ligase -
  FGL12_RS10615 (NCTC9124_02142) lytF 2183084..2184733 (+) 1650 WP_138101396.1 GBS Bsp-like repeat-containing protein Regulator
  FGL12_RS10620 (NCTC9124_02143) comB 2184852..2186210 (-) 1359 WP_138101398.1 competence pheromone export protein ComB Regulator
  FGL12_RS10625 (NCTC9124_02144) comA 2186220..2188373 (-) 2154 WP_138101400.1 peptide cleavage/export ABC transporter ComA Regulator
  FGL12_RS10630 (NCTC9124_02145) rpsD 2188827..2189438 (-) 612 WP_008810013.1 30S ribosomal protein S4 -
  FGL12_RS10635 (NCTC9124_02146) - 2189704..2190426 (-) 723 WP_008810014.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 49783.05 Da        Isoelectric Point: 6.5115

>NTDB_id=1127535 FGL12_RS10620 WP_138101398.1 2184852..2186210(-) (comB) [Streptococcus gordonii strain NCTC9124]
MNEQFLESAEFYQKRYHNFASCLIVPSLILLVFLVGFSMLAKKEITISSRASVEASRVLAQIQSTSNQAIIANHLAENKE
VKKGDLLIQYAVEGEGAQEQKFSSQLDLLKDQKGKLETLRSSLESGRNQFTEPDSYGYEQSFKDYQNQVASMTSSVNQQN
ATIASQNAAASQSQAELGGVISDVDSKLNDHRNLKNAIQSGVGIDASHPLHSLYQSYRDQLSLAEDKTTAQSQIVAQLDG
QISQLEATAATYRVQYAGAGAQQAYASNLSSQLASLKAQYLVKVGQELTTLTQQILEAESNLKLQETVSKRGQILAEMDG
LLHLNPEVQGSTLVAEGTALAQIYPKITSERKIKIVTYVSSKDVSTIKNGDKVRFITADDANKQMILTSQISSIDANATQ
TKQGNFFKVECEMAVSKDQAKKLRYGLEGKFVMVTGQKTYFSYYMEKFFNLG

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=1127535 FGL12_RS10620 WP_138101398.1 2184852..2186210(-) (comB) [Streptococcus gordonii strain NCTC9124]
ATGAATGAACAATTTTTAGAAAGTGCAGAGTTTTATCAGAAACGTTATCATAATTTTGCTAGTTGTTTAATTGTGCCAAG
TCTTATTTTACTAGTATTTCTAGTTGGTTTTTCCATGCTGGCTAAAAAGGAAATTACGATTTCTAGCCGTGCTTCTGTAG
AAGCTAGCCGAGTGCTAGCTCAGATTCAGTCAACTAGTAACCAGGCTATCATTGCGAATCATTTGGCAGAAAACAAGGAG
GTCAAAAAAGGGGACCTGCTAATCCAGTATGCAGTAGAAGGAGAGGGAGCTCAGGAACAGAAGTTTTCCAGCCAGCTTGA
CTTACTCAAAGATCAAAAGGGCAAACTAGAAACTTTGCGTTCCAGTTTAGAAAGTGGGCGTAATCAATTCACTGAGCCAG
ATAGTTATGGCTATGAACAGAGCTTTAAAGACTACCAGAACCAAGTAGCGAGTATGACTAGTTCTGTGAATCAGCAAAAT
GCTACGATTGCTTCACAAAATGCAGCGGCCAGTCAGTCTCAGGCGGAACTGGGCGGTGTTATCAGTGATGTGGATAGCAA
ACTAAATGACCATCGAAACTTGAAAAATGCCATTCAAAGTGGGGTAGGTATAGATGCATCGCATCCTCTTCACTCCCTGT
ACCAGTCCTATCGTGATCAGTTGAGTTTAGCAGAGGATAAGACTACAGCTCAAAGTCAGATTGTAGCTCAATTAGATGGG
CAAATCTCTCAATTAGAAGCAACAGCTGCGACTTATCGTGTCCAATATGCTGGTGCAGGCGCCCAACAAGCCTATGCTAG
CAATTTATCCAGTCAGTTGGCTTCACTGAAAGCCCAGTATCTGGTCAAGGTAGGACAAGAATTGACCACTCTGACTCAGC
AAATCTTGGAAGCCGAGAGTAATCTTAAACTTCAAGAAACAGTCTCTAAGCGAGGTCAGATTTTGGCTGAAATGGATGGC
TTGCTTCACTTAAATCCAGAAGTACAAGGATCCACTCTGGTGGCAGAAGGAACAGCTTTGGCTCAGATTTATCCTAAAAT
CACCAGTGAACGAAAAATCAAAATTGTCACATATGTCTCTTCCAAGGATGTATCTACTATTAAAAATGGAGATAAGGTGC
GCTTTATCACAGCTGATGATGCTAACAAACAAATGATTTTGACATCCCAAATTTCCAGTATTGACGCCAATGCTACCCAA
ACCAAACAGGGAAATTTCTTTAAAGTAGAATGCGAAATGGCTGTTAGTAAAGATCAAGCTAAGAAGCTCCGCTATGGCTT
GGAAGGTAAATTCGTCATGGTAACTGGGCAAAAGACTTATTTCAGCTATTATATGGAGAAGTTTTTTAATCTTGGTTGA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(314-426)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus gordonii str. Challis substr. CH1

98.673

100

0.987
  comB Streptococcus pneumoniae Rx1

55.778

99.558

0.555
  comB Streptococcus pneumoniae D39

55.778

99.558

0.555
  comB Streptococcus pneumoniae R6

55.778

99.558

0.555
  comB Streptococcus mitis NCTC 12261

55.556

99.558

0.553
  comB Streptococcus pneumoniae TIGR4

55.333

99.558

0.551
  comB Streptococcus mitis SK321

54.889

99.558

0.546

Multiple sequence alignment