Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | FGK96_RS04505 | Genome accession | NZ_LR594036 |
| Coordinates | 948582..949421 (+) | Length | 279 a.a. |
| NCBI ID | WP_138081761.1 | Uniprot ID | - |
| Organism | Streptococcus porcinus strain NCTC10710 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 896005..995011 | 948582..949421 | within | 0 |
Gene organization within MGE regions
Location: 896005..995011
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FGK96_RS04305 (NCTC10710_00887) | - | 898784..899287 (+) | 504 | WP_232045792.1 | hypothetical protein | - |
| FGK96_RS04310 (NCTC10710_00888) | - | 899359..900534 (-) | 1176 | WP_138080574.1 | IS110 family transposase | - |
| FGK96_RS04315 (NCTC10710_00889) | - | 900808..901767 (+) | 960 | WP_138081725.1 | single-stranded DNA-binding protein | - |
| FGK96_RS04320 (NCTC10710_00890) | - | 901925..902410 (+) | 486 | WP_012679616.1 | hypothetical protein | - |
| FGK96_RS04325 (NCTC10710_00891) | - | 902520..903895 (-) | 1376 | Protein_806 | relaxase/mobilization nuclease domain-containing protein | - |
| FGK96_RS04330 (NCTC10710_00892) | - | 903895..904263 (-) | 369 | WP_012679614.1 | plasmid mobilization protein | - |
| FGK96_RS04335 (NCTC10710_00893) | - | 904797..905177 (+) | 381 | WP_091993273.1 | metal-dependent transcriptional regulator | - |
| FGK96_RS04340 (NCTC10710_00894) | - | 905405..906154 (+) | 750 | WP_026624789.1 | thioesterase II family protein | - |
| FGK96_RS04345 (NCTC10710_00895) | - | 906141..906824 (+) | 684 | WP_138081727.1 | 4'-phosphopantetheinyl transferase family protein | - |
| FGK96_RS04350 (NCTC10710_00896) | - | 906833..908416 (+) | 1584 | WP_138081729.1 | (2,3-dihydroxybenzoyl)adenylate synthase | - |
| FGK96_RS04355 (NCTC10710_00897) | - | 908431..914613 (+) | 6183 | WP_138081731.1 | non-ribosomal peptide synthetase | - |
| FGK96_RS04360 (NCTC10710_00898) | - | 914624..916042 (+) | 1419 | WP_117279717.1 | condensation domain-containing protein | - |
| FGK96_RS04365 (NCTC10710_00899) | - | 916060..917076 (+) | 1017 | WP_026624707.1 | alpha/beta hydrolase family protein | - |
| FGK96_RS04370 (NCTC10710_00900) | - | 917081..917350 (+) | 270 | WP_026624708.1 | acyl carrier protein | - |
| FGK96_RS04375 (NCTC10710_00901) | - | 917350..922272 (+) | 4923 | WP_138081733.1 | AMP-binding protein | - |
| FGK96_RS04380 (NCTC10710_00902) | - | 922265..923233 (+) | 969 | WP_026624710.1 | hypothetical protein | - |
| FGK96_RS04385 (NCTC10710_00903) | - | 923250..924335 (+) | 1086 | WP_081654695.1 | Gfo/Idh/MocA family oxidoreductase | - |
| FGK96_RS04390 (NCTC10710_00904) | - | 924352..925062 (+) | 711 | WP_026624712.1 | class I SAM-dependent methyltransferase | - |
| FGK96_RS04395 (NCTC10710_00905) | - | 925169..925807 (+) | 639 | WP_138081735.1 | TetR/AcrR family transcriptional regulator | - |
| FGK96_RS04400 (NCTC10710_00906) | - | 925930..926526 (+) | 597 | WP_009530392.1 | MptD family putative ECF transporter S component | - |
| FGK96_RS04405 (NCTC10710_00907) | - | 926516..927229 (+) | 714 | WP_009530368.1 | energy-coupling factor transporter transmembrane component T family protein | - |
| FGK96_RS04410 (NCTC10710_00908) | - | 927214..928683 (+) | 1470 | WP_138081737.1 | ABC transporter ATP-binding protein | - |
| FGK96_RS04415 (NCTC10710_00909) | - | 928673..930463 (+) | 1791 | WP_138081739.1 | ABC transporter ATP-binding protein | - |
| FGK96_RS04420 (NCTC10710_00910) | - | 930456..932201 (+) | 1746 | WP_138081741.1 | ABC transporter ATP-binding protein | - |
| FGK96_RS04425 (NCTC10710_00911) | - | 932233..932748 (+) | 516 | Protein_826 | MATE family efflux transporter | - |
| FGK96_RS04430 | - | 932779..934105 (-) | 1327 | Protein_827 | IS3 family transposase | - |
| FGK96_RS04435 (NCTC10710_00915) | - | 934158..934997 (+) | 840 | Protein_828 | MATE family efflux transporter | - |
| FGK96_RS04440 (NCTC10710_00916) | - | 935315..935716 (+) | 402 | WP_117279702.1 | sigma-70 family RNA polymerase sigma factor | - |
| FGK96_RS04445 (NCTC10710_00917) | - | 936171..936338 (+) | 168 | WP_026624720.1 | hypothetical protein | - |
| FGK96_RS04450 (NCTC10710_00918) | - | 936476..938155 (+) | 1680 | WP_420031111.1 | recombinase family protein | - |
| FGK96_RS04455 (NCTC10710_00919) | - | 938148..939899 (+) | 1752 | WP_138081745.1 | recombinase family protein | - |
| FGK96_RS04460 (NCTC10710_00920) | - | 939892..941412 (+) | 1521 | WP_117279696.1 | recombinase family protein | - |
| FGK96_RS04465 (NCTC10710_00921) | - | 941453..942877 (+) | 1425 | Protein_834 | ABC-F family ATP-binding cassette domain-containing protein | - |
| FGK96_RS10445 (NCTC10710_00922) | - | 943190..943342 (+) | 153 | WP_172601593.1 | hypothetical protein | - |
| FGK96_RS04470 (NCTC10710_00923) | - | 943352..943699 (+) | 348 | WP_138081747.1 | hypothetical protein | - |
| FGK96_RS04475 (NCTC10710_00924) | - | 944006..944917 (-) | 912 | WP_138081749.1 | diacylglycerol/lipid kinase family protein | - |
| FGK96_RS04480 (NCTC10710_00925) | trhA | 945018..945668 (-) | 651 | WP_138081751.1 | PAQR family membrane homeostasis protein TrhA | - |
| FGK96_RS04485 (NCTC10710_00926) | - | 945682..946110 (-) | 429 | WP_138081753.1 | DUF1836 domain-containing protein | - |
| FGK96_RS04490 (NCTC10710_00927) | ylqF | 946288..947151 (+) | 864 | WP_138081755.1 | ribosome biogenesis GTPase YlqF | - |
| FGK96_RS04495 (NCTC10710_00928) | - | 947126..947902 (+) | 777 | WP_138081757.1 | ribonuclease HII | - |
| FGK96_RS04500 (NCTC10710_00929) | - | 947960..948508 (+) | 549 | WP_138081759.1 | sugar O-acetyltransferase | - |
| FGK96_RS04505 (NCTC10710_00930) | dprA | 948582..949421 (+) | 840 | WP_138081761.1 | DNA-processing protein DprA | Machinery gene |
| FGK96_RS04510 (NCTC10710_00931) | topA | 949525..951651 (+) | 2127 | WP_138081763.1 | type I DNA topoisomerase | - |
| FGK96_RS04515 (NCTC10710_00932) | - | 951842..952726 (-) | 885 | WP_138081765.1 | LysR family transcriptional regulator | - |
| FGK96_RS04520 (NCTC10710_00933) | - | 952937..953995 (+) | 1059 | WP_138081767.1 | PTS transporter subunit IIC | - |
| FGK96_RS04525 (NCTC10710_00934) | - | 954011..955003 (+) | 993 | WP_138081769.1 | D-lactate dehydrogenase | - |
| FGK96_RS04530 (NCTC10710_00935) | - | 955149..955820 (+) | 672 | WP_138081771.1 | SatD family protein | - |
| FGK96_RS04535 (NCTC10710_00936) | - | 955817..956533 (+) | 717 | WP_138081773.1 | DUF3307 domain-containing protein | - |
| FGK96_RS04540 (NCTC10710_00937) | trmFO | 956660..957994 (+) | 1335 | WP_138081775.1 | methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO | - |
| FGK96_RS04545 (NCTC10710_00938) | - | 958157..958642 (-) | 486 | WP_138081777.1 | PASTA domain-containing protein | - |
| FGK96_RS04550 (NCTC10710_00939) | - | 958842..959594 (+) | 753 | WP_138081779.1 | ABC transporter ATP-binding protein | - |
| FGK96_RS04555 (NCTC10710_00940) | - | 959596..961551 (+) | 1956 | WP_138081781.1 | FtsX-like permease family protein | - |
| FGK96_RS04560 (NCTC10710_00941) | - | 961595..962260 (+) | 666 | WP_138081783.1 | response regulator transcription factor | - |
| FGK96_RS04565 (NCTC10710_00942) | - | 962257..963201 (+) | 945 | WP_138081785.1 | sensor histidine kinase | - |
| FGK96_RS10560 (NCTC10710_00943) | - | 963205..963405 (+) | 201 | WP_232045793.1 | DUF5655 domain-containing protein | - |
| FGK96_RS04575 (NCTC10710_00944) | - | 963497..963769 (+) | 273 | WP_197733240.1 | hypothetical protein | - |
| FGK96_RS04580 (NCTC10710_00945) | xerS | 963894..964964 (-) | 1071 | WP_138081787.1 | tyrosine recombinase XerS | - |
| FGK96_RS04585 (NCTC10710_00946) | - | 965184..965630 (-) | 447 | WP_138081789.1 | threonine/serine exporter family protein | - |
| FGK96_RS04590 (NCTC10710_00947) | - | 965621..966406 (-) | 786 | WP_138081791.1 | threonine/serine ThrE exporter family protein | - |
| FGK96_RS04595 (NCTC10710_00948) | - | 966669..967091 (-) | 423 | WP_138081793.1 | cupin domain-containing protein | - |
| FGK96_RS04600 (NCTC10710_00949) | - | 967332..968183 (+) | 852 | WP_138081795.1 | MurR/RpiR family transcriptional regulator | - |
| FGK96_RS04605 (NCTC10710_00950) | - | 968221..968595 (-) | 375 | WP_138081797.1 | pyridoxamine 5'-phosphate oxidase family protein | - |
| FGK96_RS04610 (NCTC10710_00951) | - | 968780..969796 (-) | 1017 | WP_138081799.1 | Gfo/Idh/MocA family oxidoreductase | - |
| FGK96_RS04615 (NCTC10710_00952) | - | 970003..970695 (+) | 693 | WP_138081801.1 | LexA family transcriptional regulator | - |
| FGK96_RS04620 | - | 970730..970837 (-) | 108 | WP_138081803.1 | IS3 family transposase | - |
| FGK96_RS04625 (NCTC10710_00953) | - | 971169..972452 (-) | 1284 | WP_138081805.1 | iron reductase | - |
| FGK96_RS04630 (NCTC10710_00954) | ffh | 972834..974387 (-) | 1554 | WP_138081807.1 | signal recognition particle protein | - |
| FGK96_RS04635 (NCTC10710_00955) | - | 974399..974731 (-) | 333 | WP_232045833.1 | putative DNA-binding protein | - |
| FGK96_RS04640 (NCTC10710_00956) | - | 974835..975533 (-) | 699 | WP_138081811.1 | GntR family transcriptional regulator | - |
| FGK96_RS04645 (NCTC10710_00957) | guaA | 975842..977404 (+) | 1563 | WP_138081813.1 | glutamine-hydrolyzing GMP synthase | - |
| FGK96_RS04650 (NCTC10710_00958) | - | 977633..978766 (+) | 1134 | WP_138081815.1 | cation:proton antiporter | - |
| FGK96_RS04655 (NCTC10710_00959) | - | 978932..980410 (+) | 1479 | WP_138081817.1 | peptide MFS transporter | - |
| FGK96_RS10450 (NCTC10710_00960) | - | 980447..980605 (-) | 159 | WP_172601594.1 | hypothetical protein | - |
| FGK96_RS04660 (NCTC10710_00961) | - | 980650..980916 (-) | 267 | WP_138081819.1 | hypothetical protein | - |
| FGK96_RS04665 (NCTC10710_00962) | - | 981293..982015 (+) | 723 | WP_138081821.1 | DUF554 domain-containing protein | - |
| FGK96_RS04670 (NCTC10710_00963) | - | 982291..983247 (-) | 957 | WP_138083498.1 | DUF1002 domain-containing protein | - |
| FGK96_RS04675 (NCTC10710_00964) | - | 983473..983886 (-) | 414 | WP_138083499.1 | VOC family protein | - |
| FGK96_RS04680 (NCTC10710_00965) | - | 983942..984700 (-) | 759 | WP_138081823.1 | class A sortase | - |
| FGK96_RS04685 (NCTC10710_00966) | gyrA | 984703..987213 (-) | 2511 | WP_138081825.1 | DNA gyrase subunit A | - |
| FGK96_RS04690 (NCTC10710_00967) | - | 987409..988392 (+) | 984 | WP_003084658.1 | L-lactate dehydrogenase | - |
| FGK96_RS04695 (NCTC10710_00968) | - | 988431..988964 (-) | 534 | WP_138081827.1 | dihydrofolate reductase family protein | - |
| FGK96_RS04700 (NCTC10710_00969) | nox | 989027..990394 (-) | 1368 | WP_138081829.1 | H2O-forming NADH oxidase | - |
| FGK96_RS04705 (NCTC10710_00970) | - | 990700..991302 (-) | 603 | WP_172601595.1 | lysozyme family protein | - |
| FGK96_RS04710 (NCTC10710_00971) | - | 991303..992280 (-) | 978 | WP_138081833.1 | nucleoid-associated protein | - |
| FGK96_RS04715 (NCTC10710_00972) | glyA | 992285..993541 (-) | 1257 | WP_138081835.1 | serine hydroxymethyltransferase | - |
| FGK96_RS04720 (NCTC10710_00973) | - | 993571..994164 (-) | 594 | WP_138081837.1 | L-threonylcarbamoyladenylate synthase | - |
| FGK96_RS04725 (NCTC10710_00974) | prmC | 994157..994987 (-) | 831 | WP_138081839.1 | peptide chain release factor N(5)-glutamine methyltransferase | - |
Sequence
Protein
Download Length: 279 a.a. Molecular weight: 31058.77 Da Isoelectric Point: 9.3055
>NTDB_id=1127343 FGK96_RS04505 WP_138081761.1 948582..949421(+) (dprA) [Streptococcus porcinus strain NCTC10710]
MNNFELYKLRKAGLKNHHILNVINYYQTYGKSLSLRNIAVASETSDPIQFIETYKAIDSKALRKEFNQYPSISLLDKNYP
SYLKEIYNPPVLLFYQGNLELLNYPKLAVVGSRKASQSGLKATQKIIEELNNKLIIVSGLARGVDTAAHCCALKTGGHTI
AVIGSGFTHYYPKENQRLQKFIASNHLLLTEYGPNDPPLSIHFSERNRIIAGLAKAVLVIEAKRRSGSLITCRYALENGR
EVFAIPGNISDGFSDGCNQLIQEGAKCIMSGLDVLTELF
MNNFELYKLRKAGLKNHHILNVINYYQTYGKSLSLRNIAVASETSDPIQFIETYKAIDSKALRKEFNQYPSISLLDKNYP
SYLKEIYNPPVLLFYQGNLELLNYPKLAVVGSRKASQSGLKATQKIIEELNNKLIIVSGLARGVDTAAHCCALKTGGHTI
AVIGSGFTHYYPKENQRLQKFIASNHLLLTEYGPNDPPLSIHFSERNRIIAGLAKAVLVIEAKRRSGSLITCRYALENGR
EVFAIPGNISDGFSDGCNQLIQEGAKCIMSGLDVLTELF
Nucleotide
Download Length: 840 bp
>NTDB_id=1127343 FGK96_RS04505 WP_138081761.1 948582..949421(+) (dprA) [Streptococcus porcinus strain NCTC10710]
ATGAATAATTTTGAACTTTATAAACTTCGAAAAGCCGGTTTGAAAAATCATCACATTTTAAATGTTATTAATTATTATCA
AACTTATGGTAAATCCCTATCTTTACGAAATATCGCAGTTGCTTCTGAAACATCGGATCCAATACAATTTATTGAAACTT
ACAAAGCAATTGATAGTAAAGCTCTGCGGAAAGAATTTAATCAGTATCCTAGTATTTCCTTACTTGATAAAAATTACCCC
TCATATTTAAAAGAAATCTATAACCCACCGGTTTTACTTTTTTACCAAGGGAATTTAGAACTTTTAAATTATCCCAAACT
AGCAGTAGTAGGCTCTCGCAAGGCGAGTCAATCAGGCCTAAAAGCGACTCAAAAAATAATAGAAGAATTAAATAATAAAC
TCATTATTGTTAGTGGTCTTGCCAGAGGAGTTGATACTGCGGCACATTGTTGTGCACTTAAAACAGGTGGTCATACAATT
GCTGTCATTGGCTCTGGTTTCACGCATTACTACCCTAAAGAAAACCAAAGATTGCAAAAATTTATTGCTTCTAATCACCT
TTTACTAACTGAATATGGACCAAATGATCCGCCATTATCCATTCATTTTTCAGAAAGAAATCGAATCATTGCTGGTTTAG
CAAAGGCGGTTTTAGTTATTGAAGCTAAAAGACGATCCGGAAGCTTAATAACATGTCGATATGCTCTTGAAAATGGTCGT
GAAGTTTTCGCAATTCCTGGAAATATTAGTGATGGTTTTTCAGATGGCTGTAATCAGCTTATTCAAGAAGGCGCAAAGTG
CATCATGAGTGGTTTGGATGTGCTTACAGAGCTTTTTTAA
ATGAATAATTTTGAACTTTATAAACTTCGAAAAGCCGGTTTGAAAAATCATCACATTTTAAATGTTATTAATTATTATCA
AACTTATGGTAAATCCCTATCTTTACGAAATATCGCAGTTGCTTCTGAAACATCGGATCCAATACAATTTATTGAAACTT
ACAAAGCAATTGATAGTAAAGCTCTGCGGAAAGAATTTAATCAGTATCCTAGTATTTCCTTACTTGATAAAAATTACCCC
TCATATTTAAAAGAAATCTATAACCCACCGGTTTTACTTTTTTACCAAGGGAATTTAGAACTTTTAAATTATCCCAAACT
AGCAGTAGTAGGCTCTCGCAAGGCGAGTCAATCAGGCCTAAAAGCGACTCAAAAAATAATAGAAGAATTAAATAATAAAC
TCATTATTGTTAGTGGTCTTGCCAGAGGAGTTGATACTGCGGCACATTGTTGTGCACTTAAAACAGGTGGTCATACAATT
GCTGTCATTGGCTCTGGTTTCACGCATTACTACCCTAAAGAAAACCAAAGATTGCAAAAATTTATTGCTTCTAATCACCT
TTTACTAACTGAATATGGACCAAATGATCCGCCATTATCCATTCATTTTTCAGAAAGAAATCGAATCATTGCTGGTTTAG
CAAAGGCGGTTTTAGTTATTGAAGCTAAAAGACGATCCGGAAGCTTAATAACATGTCGATATGCTCTTGAAAATGGTCGT
GAAGTTTTCGCAATTCCTGGAAATATTAGTGATGGTTTTTCAGATGGCTGTAATCAGCTTATTCAAGAAGGCGCAAAGTG
CATCATGAGTGGTTTGGATGTGCTTACAGAGCTTTTTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Streptococcus mutans UA159 |
64.029 |
99.642 |
0.638 |
| dprA/cilB/dalA | Streptococcus mitis SK321 |
57.554 |
99.642 |
0.573 |
| dprA/cilB/dalA | Streptococcus pneumoniae Rx1 |
57.194 |
99.642 |
0.57 |
| dprA/cilB/dalA | Streptococcus pneumoniae D39 |
57.194 |
99.642 |
0.57 |
| dprA/cilB/dalA | Streptococcus pneumoniae R6 |
57.194 |
99.642 |
0.57 |
| dprA/cilB/dalA | Streptococcus pneumoniae TIGR4 |
57.194 |
99.642 |
0.57 |
| dprA/cilB/dalA | Streptococcus mitis NCTC 12261 |
56.835 |
99.642 |
0.566 |
| dprA | Lactococcus lactis subsp. cremoris KW2 |
52.708 |
99.283 |
0.523 |
| dprA | Legionella pneumophila strain ERS1305867 |
38.408 |
100 |
0.398 |
| dprA | Bacillus subtilis subsp. subtilis str. 168 |
40.873 |
90.323 |
0.369 |
| dprA | Latilactobacillus sakei subsp. sakei 23K |
40.8 |
89.606 |
0.366 |