Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   FGL04_RS05480 Genome accession   NZ_LR594035
Coordinates   1033686..1034525 (+) Length   279 a.a.
NCBI ID   WP_138068476.1    Uniprot ID   A0A4U9YG75
Organism   Streptococcus pseudoporcinus strain NCTC5385     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1025451..1054721 1033686..1034525 within 0


Gene organization within MGE regions


Location: 1025451..1054721
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL04_RS05435 (NCTC5385_01182) - 1025451..1025924 (+) 474 WP_138068472.1 PTS sugar transporter subunit IIA -
  FGL04_RS05440 (NCTC5385_01183) - 1026028..1027163 (-) 1136 Protein_1063 IS3 family transposase -
  FGL04_RS05445 (NCTC5385_01185) - 1027350..1027547 (+) 198 Protein_1064 site-specific integrase -
  FGL04_RS05460 (NCTC5385_01190) - 1030014..1031326 (+) 1313 Protein_1067 tyrosine-type recombinase/integrase -
  FGL04_RS05465 (NCTC5385_01191) ylqF 1031406..1032269 (+) 864 WP_138068473.1 ribosome biogenesis GTPase YlqF -
  FGL04_RS05470 (NCTC5385_01192) - 1032244..1033017 (+) 774 WP_138068474.1 ribonuclease HII -
  FGL04_RS05475 (NCTC5385_01193) - 1033064..1033612 (+) 549 WP_138068475.1 sugar O-acetyltransferase -
  FGL04_RS05480 (NCTC5385_01194) dprA 1033686..1034525 (+) 840 WP_138068476.1 DNA-processing protein DprA Machinery gene
  FGL04_RS05485 (NCTC5385_01195) topA 1034629..1036761 (+) 2133 WP_138068477.1 type I DNA topoisomerase -
  FGL04_RS05490 (NCTC5385_01196) - 1037165..1038049 (-) 885 WP_138068478.1 LysR family transcriptional regulator -
  FGL04_RS05495 (NCTC5385_01197) - 1038259..1039317 (+) 1059 WP_138068479.1 PTS transporter subunit IIC -
  FGL04_RS05500 (NCTC5385_01198) - 1039340..1040332 (+) 993 WP_138068480.1 D-lactate dehydrogenase -
  FGL04_RS05505 (NCTC5385_01199) - 1040479..1041153 (+) 675 WP_138068481.1 SatD family protein -
  FGL04_RS05510 (NCTC5385_01200) - 1041146..1041862 (+) 717 WP_138068482.1 DUF3307 domain-containing protein -
  FGL04_RS05515 (NCTC5385_01201) trmFO 1041989..1043323 (+) 1335 WP_171011246.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  FGL04_RS05520 (NCTC5385_01202) - 1043351..1043836 (-) 486 WP_138068484.1 PASTA domain-containing protein -
  FGL04_RS05525 (NCTC5385_01203) - 1044042..1044794 (+) 753 WP_138068485.1 ABC transporter ATP-binding protein -
  FGL04_RS05530 - 1044796..1046456 (+) 1661 Protein_1081 FtsX-like permease family protein -
  FGL04_RS05535 (NCTC5385_01206) - 1046567..1047004 (+) 438 Protein_1082 response regulator transcription factor -
  FGL04_RS11370 (NCTC5385_01207) - 1047001..1047413 (+) 413 Protein_1083 hypothetical protein -
  FGL04_RS05545 (NCTC5385_01209) xerS 1047541..1048611 (-) 1071 WP_138068486.1 tyrosine recombinase XerS -
  FGL04_RS05550 (NCTC5385_01210) - 1048847..1049293 (-) 447 WP_077323584.1 threonine/serine exporter family protein -
  FGL04_RS05555 (NCTC5385_01211) - 1049290..1050069 (-) 780 WP_138068487.1 threonine/serine ThrE exporter family protein -
  FGL04_RS05560 (NCTC5385_01212) - 1050343..1050765 (-) 423 WP_007891427.1 cupin domain-containing protein -
  FGL04_RS10775 - 1050872..1051012 (+) 141 WP_171011248.1 hypothetical protein -
  FGL04_RS05570 (NCTC5385_01215) - 1052813..1053829 (-) 1017 WP_138068488.1 Gfo/Idh/MocA family oxidoreductase -
  FGL04_RS05575 (NCTC5385_01216) - 1054029..1054721 (+) 693 WP_138068489.1 LexA family transcriptional regulator -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 31163.04 Da        Isoelectric Point: 9.1949

>NTDB_id=1127301 FGL04_RS05480 WP_138068476.1 1033686..1034525(+) (dprA) [Streptococcus pseudoporcinus strain NCTC5385]
MNNFELYKLRKAGLKNHHILNVINYYQTYGKSLSLRNMAVASETSDPIQFIETYKTINSKALRKEFNQYPSISLLDKNYP
SLLKEIYNPPVLLFYQGDLELLNYTKLAVVGSRKSSPLGLKVTQKIIEELNNKLIIVSGLARGVDTAAHCCALKTGGRTI
AVIGSGFNHYYPKENQRLQKFIASNHLLLTEYGPNDPPLSIHFPERNRIIACLVKAVLVIEAKSRSGSLITCRYALENGR
EVFAVPGNISDSFSDGCNQLIQEGAKCIMSGLDVLTELF

Nucleotide


Download         Length: 840 bp        

>NTDB_id=1127301 FGL04_RS05480 WP_138068476.1 1033686..1034525(+) (dprA) [Streptococcus pseudoporcinus strain NCTC5385]
ATGAATAATTTTGAACTTTACAAACTTCGAAAAGCAGGTTTGAAAAACCATCACATTTTAAATGTCATTAATTATTACCA
AACTTATGGTAAATCCCTATCTTTACGGAATATGGCGGTCGCTTCTGAGACATCAGATCCTATACAATTTATTGAAACTT
ATAAAACAATTAATAGTAAAGCTTTGCGGAAAGAATTTAATCAGTATCCTAGTATTTCCCTCCTTGATAAAAATTATCCC
TCGCTTTTAAAAGAAATCTATAATCCACCGGTTTTACTTTTTTATCAAGGAGATTTAGAACTTTTAAATTATACAAAACT
AGCGGTGGTAGGCTCCCGCAAATCTAGTCCATTAGGCTTAAAAGTAACTCAAAAAATAATAGAAGAATTAAATAATAAAC
TCATTATTGTCAGTGGACTTGCTAGAGGTGTCGATACTGCGGCACATTGTTGTGCGCTTAAAACGGGTGGTCGTACAATT
GCTGTCATTGGCTCGGGTTTCAATCATTATTACCCTAAAGAAAACCAGAGGTTGCAAAAATTTATTGCGTCTAATCACCT
TTTATTAACAGAATATGGCCCAAATGATCCTCCTTTATCTATTCATTTTCCAGAGAGGAATCGGATTATTGCTTGCCTAG
TTAAAGCAGTGCTAGTTATTGAAGCTAAAAGCCGGTCTGGAAGTTTAATAACATGCCGGTACGCCCTTGAAAATGGTCGC
GAAGTTTTTGCTGTTCCTGGAAATATTAGCGATAGTTTTTCCGATGGTTGTAATCAACTTATCCAAGAAGGTGCAAAGTG
CATCATGAGTGGTTTGGATGTGCTTACAGAACTTTTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)

DNA recombination-mediator protein A (DNA_processg_A)

(71-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9YG75

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus mitis SK321

55.396

99.642

0.552
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

55.036

99.642

0.548
  dprA/cilB/dalA Streptococcus pneumoniae D39

55.036

99.642

0.548
  dprA/cilB/dalA Streptococcus pneumoniae R6

55.036

99.642

0.548
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

55.036

99.642

0.548
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

54.676

99.642

0.545
  dprA Lactococcus lactis subsp. cremoris KW2

50.181

99.283

0.498
  dprA Bacillus subtilis subsp. subtilis str. 168

42.46

90.323

0.384
  dprA Legionella pneumophila strain ERS1305867

41.564

87.097

0.362

Multiple sequence alignment