Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   FGK99_RS02490 Genome accession   NZ_LR594033
Coordinates   519613..520980 (+) Length   455 a.a.
NCBI ID   WP_138118891.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC4675     
Function   transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 515491..525828 519613..520980 within 0


Gene organization within MGE regions


Location: 515491..525828
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK99_RS02475 (NCTC4675_00504) - 516469..516609 (+) 141 WP_138118885.1 competence protein -
  FGK99_RS10050 (NCTC4675_00505) - 516722..516880 (+) 159 WP_021320463.1 hypothetical protein -
  FGK99_RS10055 (NCTC4675_00506) - 516894..517040 (+) 147 WP_021320464.1 hypothetical protein -
  FGK99_RS02480 (NCTC4675_00507) - 517063..517230 (+) 168 WP_138118887.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  FGK99_RS02485 (NCTC4675_00508) comA 517457..519598 (+) 2142 WP_138118889.1 peptide cleavage/export ABC transporter ComA Regulator
  FGK99_RS02490 (NCTC4675_00509) comB 519613..520980 (+) 1368 WP_138118891.1 bacteriocin secretion accessory protein Regulator
  FGK99_RS02495 (NCTC4675_00510) - 521489..521725 (+) 237 WP_024273149.1 hypothetical protein -
  FGK99_RS02500 (NCTC4675_00511) nrdF 522183..523196 (+) 1014 WP_012678369.1 class 1b ribonucleoside-diphosphate reductase subunit beta -
  FGK99_RS02505 (NCTC4675_00512) nrdI 523198..523608 (+) 411 WP_138119984.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  FGK99_RS02510 (NCTC4675_00513) nrdE 523654..525828 (+) 2175 WP_138118893.1 class 1b ribonucleoside-diphosphate reductase subunit alpha -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50821.93 Da        Isoelectric Point: 5.3426

>NTDB_id=1127169 FGK99_RS02490 WP_138118891.1 519613..520980(+) (comB) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MNNNILESAEFYNRRYHNFSSRVILPTLLLFLFGVFFLAFAKKEISIISTATVEPNIILSNIQSTSNNTILTNNLKDNKY
VKFGDLLIKYDSRKEGIQQETYQTQLNNLQIQKEQLELLKASIEAGNSQFPEKDNYGYYQTFIDYLNQINTLSANVNQQN
ENVSSQNTAASNQQVEIENAIKGLTSQISDYQSVRSAIQNGTVVDLDNRAYSIYRSYLTQTSSLVDNTDKTAVINQFVAQ
IDSQINQLESSVAGYRIQHAGSGVQQSYSSTLESQLASLKAQSITKVEQELSALSNQITELEGTNKLQKNTSSKTSIVAN
EDGVLHLNQEFIGANIVPEGTIFAQVYPEMKKGTVVKITGYLPSTEISSISIGDTARFSTKDDNGETLDLIVKLSSIDNA
ATKTKNGNYFKVESKLHLKEKEAQLLKYGLEGKFILITGTKSYLNYYIDKFIGEK

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=1127169 FGK99_RS02490 WP_138118891.1 519613..520980(+) (comB) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGAATAACAATATATTAGAAAGTGCGGAATTTTATAACCGTCGTTACCACAACTTTTCTAGTCGTGTCATTCTACCTAC
TTTGCTGCTTTTCTTGTTTGGTGTTTTCTTCCTAGCATTTGCAAAGAAAGAAATTTCTATTATTTCAACTGCAACAGTTG
AACCAAATATAATTCTTTCCAATATTCAATCTACAAGTAATAATACAATATTAACCAATAATCTAAAAGATAATAAATAT
GTCAAATTTGGAGACTTATTGATAAAATATGATTCAAGAAAAGAAGGTATTCAACAAGAGACCTATCAAACTCAATTAAA
TAATTTACAAATCCAAAAAGAACAGTTAGAGCTATTAAAAGCAAGTATTGAAGCTGGAAACAGTCAATTTCCAGAAAAAG
ATAATTATGGATATTATCAAACATTTATTGACTACTTAAATCAGATAAACACCTTATCAGCCAATGTAAATCAGCAAAAT
GAAAATGTCTCTTCACAAAATACTGCAGCTAGCAATCAGCAAGTAGAAATTGAGAATGCCATCAAAGGTCTCACAAGTCA
AATTTCAGATTATCAATCTGTTCGCTCGGCGATTCAAAATGGAACAGTGGTAGATCTTGATAATCGGGCTTATTCTATCT
ATAGGAGTTATCTAACTCAAACATCGAGTTTGGTAGATAATACTGATAAAACCGCTGTTATTAATCAATTTGTTGCTCAA
ATTGATAGTCAGATCAATCAACTAGAGAGTAGTGTAGCTGGTTATCGGATTCAGCATGCTGGTTCAGGAGTGCAACAATC
TTACTCTTCAACTCTAGAGAGTCAACTGGCTTCCTTAAAAGCGCAAAGCATAACCAAAGTTGAGCAAGAGTTGTCTGCTT
TGTCGAATCAAATTACAGAATTAGAGGGAACAAATAAACTTCAGAAGAACACATCATCTAAGACCTCTATAGTTGCCAAT
GAAGATGGTGTGTTGCATCTTAATCAGGAATTTATTGGTGCAAATATTGTTCCTGAAGGAACAATATTTGCTCAAGTTTA
TCCAGAAATGAAAAAAGGAACTGTTGTAAAAATCACAGGTTATTTACCTTCGACGGAAATATCAAGTATTTCTATTGGAG
ATACAGCACGATTTTCCACGAAAGATGATAATGGCGAAACTCTTGATTTAATAGTTAAATTATCTAGTATTGACAATGCT
GCAACTAAAACAAAAAATGGGAATTATTTTAAAGTTGAATCTAAGTTACATCTTAAAGAAAAAGAAGCTCAATTATTGAA
ATATGGGCTTGAGGGTAAATTTATTTTAATTACGGGAACAAAAAGTTACTTGAATTACTATATTGATAAATTTATCGGTG
AGAAGTAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(317-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

50.221

99.341

0.499
  comB Streptococcus pneumoniae D39

50.221

99.341

0.499
  comB Streptococcus pneumoniae R6

50.221

99.341

0.499
  comB Streptococcus pneumoniae TIGR4

49.336

99.341

0.49
  comB Streptococcus mitis NCTC 12261

49.115

99.341

0.488
  comB Streptococcus mitis SK321

48.894

99.341

0.486
  comB Streptococcus gordonii str. Challis substr. CH1

47.894

99.121

0.475

Multiple sequence alignment